Skip to main content
Top
Published in: BMC Musculoskeletal Disorders 1/2013

Open Access 01-12-2013 | Research article

Estimation of 10 - year probability bone fracture in a selected sample of Palestinian people using fracture risk assessment tool

Authors: Mai B Aker, Adham S Abu Taha, Sa’ed H Zyoud, Ansam F Sawalha, Samah W Al-Jabi, Waleed M Sweileh

Published in: BMC Musculoskeletal Disorders | Issue 1/2013

Login to get access

Abstract

Background

The Fracture Risk Assessment (FRAX) tool has been developed by the World Health Organization (WHO) to calculate 10-year probability hip fracture (HP) or major osteoporotic fracture (MOF). The objective of this study was to assess the 10-year probability of MOF and HF among a selected sample of Palestinian people.

Methods

A sample of 100 subjects was studied. Dual energy X-ray absorpitometry was performed to measure bone mineral density (BMD) which was then inserted into FRAX Palestine online WHO tool to calculate the 10-year probability of MOF and HF.

Results

The median age of participants was 61.5 years and the majority (79%) were females. The median (interquartile range) of femoral hip BMD was 0.82 (0.76-0.92) g/cm2. The mean vertebral and hip T scores were -1.41 ± 0.13 SDs and -0.91 ± 0.10 SDs respectively. About one fifth of the sample (21%) had vertebral osteoporosis and 5% had hip osteoporosis. The median (interquartile range) 10-year probability of MOF and HF based on BMD were 3.7 (2.43-6.18)%, and 0.30 (0.10-0.68)% respectively.

Conclusion

Osteoporosis is common among Palestinian people above 50 years old. Bone fracture prevention strategies and research should be a priority in Palestine. Using FRAX might be a helpful screening tool in primary healthcare centres in Palestine.
Appendix
Available only for authorised users
Literature
1.
go back to reference Siris ES, Boonen S, Mitchell PJ, Bilezikian J, Silverman S: What's in a name? what constitutes the clinical diagnosis of osteoporosis?. Osteoporos Int. 2012, 23 (8): 2093-2097. 10.1007/s00198-012-1991-0.CrossRefPubMed Siris ES, Boonen S, Mitchell PJ, Bilezikian J, Silverman S: What's in a name? what constitutes the clinical diagnosis of osteoporosis?. Osteoporos Int. 2012, 23 (8): 2093-2097. 10.1007/s00198-012-1991-0.CrossRefPubMed
2.
go back to reference Jiang E, Wang Z, Meng Q, Li S, Wang F, Shao G, Zhang L: Study on bone density at various skeletal sites for the diagnosis of primary osteoporosis. Cell Biochem Biophys. 2012, 64 (1): 1-3. 10.1007/s12013-012-9361-2.CrossRefPubMed Jiang E, Wang Z, Meng Q, Li S, Wang F, Shao G, Zhang L: Study on bone density at various skeletal sites for the diagnosis of primary osteoporosis. Cell Biochem Biophys. 2012, 64 (1): 1-3. 10.1007/s12013-012-9361-2.CrossRefPubMed
3.
go back to reference Jin H, Lu Y: Cost-saving tree-structured survival analysis for hip fracture of study of osteoporotic fractures data. Med Decis Making. 2010, 31 (2): 299-307.CrossRefPubMed Jin H, Lu Y: Cost-saving tree-structured survival analysis for hip fracture of study of osteoporotic fractures data. Med Decis Making. 2010, 31 (2): 299-307.CrossRefPubMed
4.
go back to reference Sahota O, Morgan N, Moran CG: The direct cost of acute hip fracture care in care home residents in the UK. Osteoporos Int. 2012, 23 (3): 917-920. 10.1007/s00198-011-1651-9.CrossRefPubMed Sahota O, Morgan N, Moran CG: The direct cost of acute hip fracture care in care home residents in the UK. Osteoporos Int. 2012, 23 (3): 917-920. 10.1007/s00198-011-1651-9.CrossRefPubMed
5.
go back to reference Riggs BL: MLI: the worldwide problem of osteoporosis: insights afforded by epidemiology. Bone. 1995, 17: 505S-511S. 10.1016/8756-3282(95)00258-4.CrossRefPubMed Riggs BL: MLI: the worldwide problem of osteoporosis: insights afforded by epidemiology. Bone. 1995, 17: 505S-511S. 10.1016/8756-3282(95)00258-4.CrossRefPubMed
6.
go back to reference Kanis JOA, Johans Son H, Borgs Röm TF, ST Röm O, McCloskey E: FRAX® J a new tool for assessing fracture risk: clinical applications and intervention thresholds. Medicographia. 2010, 32: 32-39. Kanis JOA, Johans Son H, Borgs Röm TF, ST Röm O, McCloskey E: FRAX® J a new tool for assessing fracture risk: clinical applications and intervention thresholds. Medicographia. 2010, 32: 32-39.
7.
go back to reference Brown JP, Josse RG: 2002 clinical practice guidelines for the diagnosis and management of osteoporosis in Canada. CMAJ. 2002, 167 (10 Suppl): S1-S34.PubMedPubMedCentral Brown JP, Josse RG: 2002 clinical practice guidelines for the diagnosis and management of osteoporosis in Canada. CMAJ. 2002, 167 (10 Suppl): S1-S34.PubMedPubMedCentral
8.
go back to reference Brown JP, Fortier M, Frame H, Lalonde A, Papaioannou A, Senikas V, Yuen CK: Canadian consensus conference on osteoporosis, 2006 update. J Obstet Gynaecol Can. 2006, 28 (2 Suppl 1): S95-S112.CrossRefPubMed Brown JP, Fortier M, Frame H, Lalonde A, Papaioannou A, Senikas V, Yuen CK: Canadian consensus conference on osteoporosis, 2006 update. J Obstet Gynaecol Can. 2006, 28 (2 Suppl 1): S95-S112.CrossRefPubMed
9.
go back to reference Dawson-Hughes BTA, Melton L: Implications of absolute fracture risk assessment for osteoporosis practice guidelines in the USA. Osteoporos Int. 2008, 19 (4): 449-458. 10.1007/s00198-008-0559-5.CrossRefPubMed Dawson-Hughes BTA, Melton L: Implications of absolute fracture risk assessment for osteoporosis practice guidelines in the USA. Osteoporos Int. 2008, 19 (4): 449-458. 10.1007/s00198-008-0559-5.CrossRefPubMed
10.
go back to reference Giacaman R, Khatib R, Shabaneh L, Ramlawi A, Sabri B, Sabatinelli G, Khawaja M, Laurance T: Health status and health services in the occupied Palestinian territory. Lancet. 2009, 373 (9666): 837-849. 10.1016/S0140-6736(09)60107-0.CrossRef Giacaman R, Khatib R, Shabaneh L, Ramlawi A, Sabri B, Sabatinelli G, Khawaja M, Laurance T: Health status and health services in the occupied Palestinian territory. Lancet. 2009, 373 (9666): 837-849. 10.1016/S0140-6736(09)60107-0.CrossRef
11.
go back to reference Cooper C, Campion G, Melton LJ: Hip fractures in the elderly: a world-wide projection. Osteoporos Int. 1992, 2 (6): 285-289. 10.1007/BF01623184.CrossRefPubMed Cooper C, Campion G, Melton LJ: Hip fractures in the elderly: a world-wide projection. Osteoporos Int. 1992, 2 (6): 285-289. 10.1007/BF01623184.CrossRefPubMed
12.
go back to reference Larijani B, Resch H, Bonjour JP, Meybodi HRA, Tehrani MRM: Osteoporosis in Iran, overview and management. Iranian Journal of Public Health. 2007, 36: 1-13. Supplement Larijani B, Resch H, Bonjour JP, Meybodi HRA, Tehrani MRM: Osteoporosis in Iran, overview and management. Iranian Journal of Public Health. 2007, 36: 1-13. Supplement
13.
go back to reference Kamel HKHM, Tariq S, Perry HM, Morley JE: Failure to diagnose and treat osteoporosis in elderly patients hospitalized with hip fracture. Am J Med. 2000, 109: 326-328. 10.1016/S0002-9343(00)00457-5.CrossRefPubMed Kamel HKHM, Tariq S, Perry HM, Morley JE: Failure to diagnose and treat osteoporosis in elderly patients hospitalized with hip fracture. Am J Med. 2000, 109: 326-328. 10.1016/S0002-9343(00)00457-5.CrossRefPubMed
14.
go back to reference El-Dessouki N: Osteoporosis in postmenopausal Saudi women using X-ray bone densitometry. Saudi Med J. 2003, 24: 935-936. El-Dessouki N: Osteoporosis in postmenopausal Saudi women using X-ray bone densitometry. Saudi Med J. 2003, 24: 935-936.
15.
go back to reference Maalouf G, Gannage-Yared MH, Ezzedine J, Larijani B, Badawi S, Rached A, Zakroui L, Masri B, Azar E, Saba E: Middle East and North Africa consensus on osteoporosis. J Musculoskelet Neuronal Interact. 2007, 7 (2): 131-143.PubMed Maalouf G, Gannage-Yared MH, Ezzedine J, Larijani B, Badawi S, Rached A, Zakroui L, Masri B, Azar E, Saba E: Middle East and North Africa consensus on osteoporosis. J Musculoskelet Neuronal Interact. 2007, 7 (2): 131-143.PubMed
16.
go back to reference Abd-Alhameed I, Saba E, Darwish HM: Prevalence and awareness of osteoporosis among postmenopausal Palestinian women. Arch Osteoporos. 2004, 5 (1–2): 111-118. Abd-Alhameed I, Saba E, Darwish HM: Prevalence and awareness of osteoporosis among postmenopausal Palestinian women. Arch Osteoporos. 2004, 5 (1–2): 111-118.
17.
go back to reference Borissova AM, Rashkov R, Boyanov M, Shinkov A, Popivanov P, Temelkova N, Vlahov J, Gavrailova M: Femoral neck bone mineral density and 10-year absolute fracture risk in a national representative sample of Bulgarian women aged 50 years and older. Arch Osteoporos. 2011, 6 (1–2): 189-195.CrossRefPubMed Borissova AM, Rashkov R, Boyanov M, Shinkov A, Popivanov P, Temelkova N, Vlahov J, Gavrailova M: Femoral neck bone mineral density and 10-year absolute fracture risk in a national representative sample of Bulgarian women aged 50 years and older. Arch Osteoporos. 2011, 6 (1–2): 189-195.CrossRefPubMed
18.
go back to reference Li YM, Liu SH: Estimation of the 10-year Probability of Osteoporotic Fracture in Postmenopausal Taiwanese Women With FRAX. Tzu Chi Medical Journal. 2010, 22 (1): 29-35. 10.1016/S1016-3190(10)60032-8.CrossRef Li YM, Liu SH: Estimation of the 10-year Probability of Osteoporotic Fracture in Postmenopausal Taiwanese Women With FRAX. Tzu Chi Medical Journal. 2010, 22 (1): 29-35. 10.1016/S1016-3190(10)60032-8.CrossRef
19.
go back to reference Pluskiewicz W, Adamczyk P, Franek E, Leszczynski P, Sewerynek E, Wichrowska H, Napiorkowska L, Kostyk T, Stuss M, Stepien-Klos W: Ten-year probability of osteoporotic fracture in 2012 Polish women assessed by FRAX and nomogram. conformity between methods and their clinical utility. Bone. 2010, 46 (6): 1661-1667. 10.1016/j.bone.2010.02.012.CrossRefPubMed Pluskiewicz W, Adamczyk P, Franek E, Leszczynski P, Sewerynek E, Wichrowska H, Napiorkowska L, Kostyk T, Stuss M, Stepien-Klos W: Ten-year probability of osteoporotic fracture in 2012 Polish women assessed by FRAX and nomogram. conformity between methods and their clinical utility. Bone. 2010, 46 (6): 1661-1667. 10.1016/j.bone.2010.02.012.CrossRefPubMed
20.
go back to reference Dawson-Hughes B: A revised clinician's guide to the prevention and treatment of osteoporosis. Journal of Clinical Endocrinology & Metabolism. 2008, 93 (7): 2463-2465. 10.1210/jc.2008-0926.CrossRef Dawson-Hughes B: A revised clinician's guide to the prevention and treatment of osteoporosis. Journal of Clinical Endocrinology & Metabolism. 2008, 93 (7): 2463-2465. 10.1210/jc.2008-0926.CrossRef
21.
go back to reference Trombetti AHF, Hoffmeyer P, Schurch M, Bonjour J, Rizzoli R: Survival and potential years of life lost after hip fracture in men and age-matched women. Osteoporos Int. 2002, 13 (9): 731-737. 10.1007/s001980200100.CrossRefPubMed Trombetti AHF, Hoffmeyer P, Schurch M, Bonjour J, Rizzoli R: Survival and potential years of life lost after hip fracture in men and age-matched women. Osteoporos Int. 2002, 13 (9): 731-737. 10.1007/s001980200100.CrossRefPubMed
22.
go back to reference Cummings SRNM, Browner WS, Stone K, Fox KM, Ensrud KE: Risk factors for hip fracture in white women. N Engl J Med. 1995, 332: 767-773. 10.1056/NEJM199503233321202.CrossRefPubMed Cummings SRNM, Browner WS, Stone K, Fox KM, Ensrud KE: Risk factors for hip fracture in white women. N Engl J Med. 1995, 332: 767-773. 10.1056/NEJM199503233321202.CrossRefPubMed
23.
go back to reference Van Staa TP LH, Abenhaim L, Zhang B, Cooper C: Oral corticosteroids and fracture risk: relationship to daily and cumulative doses. Rheumatology (Oxford). 2000, 39: 1383-1389. 10.1093/rheumatology/39.12.1383.CrossRef Van Staa TP LH, Abenhaim L, Zhang B, Cooper C: Oral corticosteroids and fracture risk: relationship to daily and cumulative doses. Rheumatology (Oxford). 2000, 39: 1383-1389. 10.1093/rheumatology/39.12.1383.CrossRef
24.
go back to reference Marshall DJO, Wedel H: Meta-analysis of how well measures of bone mineral density predict occurrence of osteoporotic fractures. BMJ. 1996, 312: 1254-1259. 10.1136/bmj.312.7041.1254.CrossRefPubMedPubMedCentral Marshall DJO, Wedel H: Meta-analysis of how well measures of bone mineral density predict occurrence of osteoporotic fractures. BMJ. 1996, 312: 1254-1259. 10.1136/bmj.312.7041.1254.CrossRefPubMedPubMedCentral
25.
go back to reference Ringe J: Osteoporosis in men. Medicographia. 2010, 32: 71-78. Ringe J: Osteoporosis in men. Medicographia. 2010, 32: 71-78.
26.
go back to reference Chrischilles EA, Butler CD, Davis CS, Wallace RB: A model of lifetime osteoporosis impact. Arch Intern Med. 1991, 151 (10): 2026-2032. 10.1001/archinte.1991.00400100100017.CrossRefPubMed Chrischilles EA, Butler CD, Davis CS, Wallace RB: A model of lifetime osteoporosis impact. Arch Intern Med. 1991, 151 (10): 2026-2032. 10.1001/archinte.1991.00400100100017.CrossRefPubMed
27.
go back to reference Abdul-Rahim HF, Holmboe-Ottesen G, Stene LC, Husseini A, Giacaman R, Jervell J, Bjertness E: Obesity in a rural and an urban Palestinian West Bank population. Int J Obes Relat Metab Disord. 2003, 27 (1): 140-146. 10.1038/sj.ijo.0802160.CrossRefPubMed Abdul-Rahim HF, Holmboe-Ottesen G, Stene LC, Husseini A, Giacaman R, Jervell J, Bjertness E: Obesity in a rural and an urban Palestinian West Bank population. Int J Obes Relat Metab Disord. 2003, 27 (1): 140-146. 10.1038/sj.ijo.0802160.CrossRefPubMed
Metadata
Title
Estimation of 10 - year probability bone fracture in a selected sample of Palestinian people using fracture risk assessment tool
Authors
Mai B Aker
Adham S Abu Taha
Sa’ed H Zyoud
Ansam F Sawalha
Samah W Al-Jabi
Waleed M Sweileh
Publication date
01-12-2013
Publisher
BioMed Central
Published in
BMC Musculoskeletal Disorders / Issue 1/2013
Electronic ISSN: 1471-2474
DOI
https://doi.org/10.1186/1471-2474-14-284

Other articles of this Issue 1/2013

BMC Musculoskeletal Disorders 1/2013 Go to the issue