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BMC Musculoskeletal Disorders
Published in: BMC Musculoskeletal Disorders 1/2010

Open Access 01-12-2010 | Research article

Risk factors of osteoporosis in healthy Moroccan men

Authors: Abdellah El Maghraoui, Merieme Ghazi, Salim Gassim, Imad Ghozlani, Aziza Mounach, Asmaa Rezqi, Mohamed Dehhaoui

Published in: BMC Musculoskeletal Disorders | Issue 1/2010

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Abstract

Background

Although not as common as in women, osteoporosis remains a significant health care problem in men. Data concerning risk factors of osteoporosis are lacking for the male Moroccan population. The objective of the study was to identify some determinants associated to low bone mineral density in Moroccan men.

Methods

a sample of 592 healthy men aged 20-79 years was recruited from the area of Rabat, the capital of Morocco. Measurements were taken at the lumbar spine and proximal femurs using DXA (Lunar Prodigy Vision, GE). Biometrical, clinical, and lifestyle determinants were collected. Univariate, multivariate, and logistic regression analyses were performed.

Results

the mean (SD) age of the patients was 49 (17.2) years old. The prevalence of osteoporosis and osteopenia were 8.7% and 52.8%, respectively. Lumbar spine and hip BMD correlated significantly with age, weight and BMI. When comparing the subjects according to the WHO classification, significant differences were revealed between the three groups of subjects for age, weight and BMI, prevalence of low calcium intake and low physical activity. The multiple regression analysis found that only age, BMI, and high coffee consumption were independently associated to the osteoporotic status.

Conclusion

ageing and low BMI are the main risk factors associated with osteoporosis in Moroccan men.
Literature
1.
Kaufman JM, Goemaere S: Osteoporosis in men. Best Pract Res Clin Endocrinol Metab. 2008, 22 (5): 787-812. 10.1016/j.beem.2008.09.005.CrossRefPubMed
2.
Mussolino ME, Gillum RF: Low bone mineral density and mortality in men and women: the Third National Health and Nutrition Examination Survey linked mortality file. Ann Epidemiol. 2008, 18 (11): 847-850. 10.1016/j.annepidem.2008.07.003.CrossRefPubMedPubMedCentral
3.
Trombetti A, Herrmann F, Hoffmeyer P, Schurch MA, Bonjour JP, Rizzoli R: Survival and potential years of life lost after hip fracture in men and age-matched women. Osteoporos Int. 2002, 13 (9): 731-737. 10.1007/s001980200100.CrossRefPubMed
4.
Center JR, Bliuc D, Nguyen TV, Eisman JA: Risk of subsequent fracture after low-trauma fracture in men and women. JAMA. 2007, 297 (4): 387-394. 10.1001/jama.297.4.387.CrossRefPubMed
5.
El Maghraoui A, Koumba BA, Jroundi I, Achemlal L, Bezza A, Tazi MA: Epidemiology of hip fractures in 2002 in Rabat, Morocco. Osteoporos Int. 2005, 16 (6): 597-602. 10.1007/s00198-004-1729-8.CrossRefPubMed
6.
El Maghraoui A, Mounach A, Gassim S, Ghazi M: Vertebral fracture assessment in healthy men: prevalence and risk factors. Bone. 2008, 43 (3): 544-548. 10.1016/j.bone.2008.05.008.CrossRefPubMed
7.
El Maghraoui A, Roux C: DXA scanning in clinical practice. QJM. 2008, 101 (8): 605-617. 10.1093/qjmed/hcn022.CrossRefPubMed
8.
Szulc P, Marchand F, Duboeuf F, Delmas PD: Cross-sectional assessment of age-related bone loss in men: the MINOS study. Bone. 2000, 26 (2): 123-129. 10.1016/S8756-3282(99)00255-0.CrossRefPubMed
9.
Kanis JA, Johnell O, Oden A, Johansson H, McCloskey E: FRAX and the assessment of fracture probability in men and women from the UK. Osteoporos Int. 2008, 19 (4): 385-397. 10.1007/s00198-007-0543-5.CrossRefPubMedPubMedCentral
10.
El Maghraoui A, Guerboub AA, Achemlal L, Mounach A, Nouijai A, Ghazi M, Bezza A, Tazi MA: Bone mineral density of the spine and femur in healthy Moroccan women. J Clin Densitom. 2006, 9 (4): 454-460. 10.1016/j.jocd.2006.07.001.CrossRefPubMed
11.
El Maghraoui A, Guerboub AA, Mounach A, Ghozlani I, Nouijai A, Ghazi M, Achemlal L, Bezza A, Tazi MA: Body mass index and gynecological factors as determinants of bone mass in healthy Moroccan women. Maturitas. 2007, 56 (4): 375-382. 10.1016/j.maturitas.2006.10.004.CrossRefPubMed
12.
El Maghraoui A, Do Santos Zounon AA, Jroundi I, Nouijai A, Ghazi M, Achemlal L, Bezza A, Tazi MA, Abouqual R: Reproducibility of bone mineral density measurements using dual X-ray absorptiometry in daily clinical practice. Osteoporos Int. 2005, 16 (12): 1742-1748. 10.1007/s00198-005-1916-2.CrossRefPubMed
13.
El Maghraoui A, Ghazi M, Gassim S, Mounach A, Ghozlani I, Nouijai A, Achemlal L, Bezza A, Dehhaoui M: Bone mineral density of the spine and femur in a group of healthy Moroccan men. Bone. 2009, 44 (5): 965-9. 10.1016/j.bone.2008.12.025.CrossRefPubMed
14.
Papaioannou A, Kennedy CC, Cranney A, Hawker G, Brown JP, Kaiser SM, Leslie WD, O'Brien CJ, Sawka AM, Khan A: Risk factors for low BMD in healthy men age 50 years or older: a systematic review. Osteoporos Int. 2008, 20 (4): 507-18. 10.1007/s00198-008-0720-1.CrossRefPubMed
15.
Liu H, Paige NM, Goldzweig CL, Wong E, Zhou A, Suttorp MJ, Munjas B, Orwoll E, Shekelle P: Screening for osteoporosis in men: a systematic review for an American College of Physicians guideline. Ann Intern Med. 2008, 148 (9): 685-701.CrossRefPubMed
16.
Hannan MT, Felson DT, Dawson-Hughes B, Tucker KL, Cupples LA, Wilson PW, Kiel DP: Risk factors for longitudinal bone loss in elderly men and women: the Framingham Osteoporosis Study. J Bone Miner Res. 2000, 15 (4): 710-720. 10.1359/jbmr.2000.15.4.710.CrossRefPubMed
17.
Tenenhouse A, Joseph L, Kreiger N, Poliquin S, Murray TM, Blondeau L, Berger C, Hanley DA, Prior JC: Estimation of the prevalence of low bone density in Canadian women and men using a population-specific DXA reference standard: the Canadian Multicentre Osteoporosis Study (CaMos). Osteoporos Int. 2000, 11 (10): 897-904. 10.1007/s001980070050.CrossRefPubMed
18.
Cauley JA, Fullman RL, Stone KL, Zmuda JM, Bauer DC, Barrett-Connor E, Ensrud K, Lau EM, Orwoll ES: Factors associated with the lumbar spine and proximal femur bone mineral density in older men. Osteoporos Int. 2005, 16 (12): 1525-1537. 10.1007/s00198-005-1866-8.CrossRefPubMed
19.
Lau EM, Leung PC, Kwok T, Woo J, Lynn H, Orwoll E, Cummings S, Cauley J: The determinants of bone mineral density in Chinese men--results from Mr. Os (Hong Kong), the first cohort study on osteoporosis in Asian men. Osteoporos Int. 2006, 17 (2): 297-303. 10.1007/s00198-005-2019-9.CrossRefPubMed
20.
Meyer HE, Sogaard AJ, Falch JA, Jorgensen L, Emaus N: Weight change over three decades and the risk of osteoporosis in men: the Norwegian Epidemiological Osteoporosis Studies (NOREPOS). Am J Epidemiol. 2008, 168 (4): 454-460. 10.1093/aje/kwn151.CrossRefPubMed
21.
Ghazi M, Mounach A, Nouijai A, Ghozlani I, Bennani L, Achemlal L, Bezza A, El Maghraoui A: Performance of the osteoporosis risk assessment tool in Moroccan men. Clin Rheumatol. 2007, 26 (12): 2037-2041. 10.1007/s10067-007-0611-4.CrossRefPubMed
22.
Adler RA, Tran MT, Petkov VI: Performance of the Osteoporosis Self-assessment Screening Tool for osteoporosis in American men. Mayo Clin Proc. 2003, 78 (6): 723-727. 10.4065/78.6.723.CrossRefPubMed
23.
Ito K, Hollenberg JP, Charlson ME: Using the osteoporosis self-assessment tool for referring older men for bone densitometry: a decision analysis. J Am Geriatr Soc. 2009, 57 (2): 218-224. 10.1111/j.1532-5415.2008.02110.x.CrossRefPubMed
24.
Cheung EY, Ho AY, Lam KF, Tam S, Kung AW: Determinants of bone mineral density in Chinese men. Osteoporos Int. 2005, 16 (12): 1481-1486. 10.1007/s00198-005-2000-7.CrossRefPubMed
25.
Bendavid EJ, Shan J, Barrett-Connor E: Factors associated with bone mineral density in middle-aged men. J Bone Miner Res. 1996, 11 (8): 1185-1190. 10.1002/jbmr.5650110818.CrossRefPubMed
26.
Lunt M, Masaryk P, Scheidt-Nave C, Nijs J, Poor G, Pols H, Falch JA, Hammermeister G, Reid DM, Benevolenskaya L: The effects of lifestyle, dietary dairy intake and diabetes on bone density and vertebral deformity prevalence: the EVOS study. Osteoporos Int. 2001, 12 (8): 688-698. 10.1007/s001980170069.CrossRefPubMed
27.
Nguyen TV, Kelly PJ, Sambrook PN, Gilbert C, Pocock NA, Eisman JA: Lifestyle factors and bone density in the elderly: implications for osteoporosis prevention. J Bone Miner Res. 1994, 9 (9): 1339-1346. 10.1002/jbmr.5650090904.CrossRefPubMed
28.
Orwoll ES, Bevan L, Phipps KR: Determinants of bone mineral density in older men. Osteoporos Int. 2000, 11 (10): 815-821. 10.1007/s001980070039.CrossRefPubMed
29.
Kung AW, Ho AY, Ross PD, Reginster JY: Development of a clinical assessment tool in identifying Asian men with low bone mineral density and comparison of its usefulness to quantitative bone ultrasound. Osteoporos Int. 2005, 16 (7): 849-855. 10.1007/s00198-004-1778-z.CrossRefPubMed
30.
Huuskonen J, Vaisanen SB, Kroger H, Jurvelin C, Bouchard C, Alhava E, Rauramaa R: Determinants of bone mineral density in middle aged men: a population-based study. Osteoporos Int. 2000, 11 (8): 702-708. 10.1007/s001980070069.CrossRefPubMed
31.
Nguyen TV, Center JR, Eisman JA: Osteoporosis in elderly men and women: effects of dietary calcium, physical activity, and body mass index. J Bone Miner Res. 2000, 15 (2): 322-331. 10.1359/jbmr.2000.15.2.322.CrossRefPubMed
32.
Kiel DP, Zhang Y, Hannan MT, Anderson JJ, Baron JA, Felson DT: The effect of smoking at different life stages on bone mineral density in elderly men and women. Osteoporos Int. 1996, 6 (3): 240-248. 10.1007/BF01622741.CrossRefPubMed
33.
Szulc P, Garnero P, Claustrat B, Marchand F, Duboeuf F, Delmas PD: Increased bone resorption in moderate smokers with low body weight: the Minos study. J Clin Endocrinol Metab. 2002, 87 (2): 666-674. 10.1210/jc.87.2.666.CrossRefPubMed
34.
May H, Murphy S, Khaw KT: Alcohol consumption and bone mineral density in older men. Gerontology. 1995, 41 (3): 152-158. 10.1159/000213676.CrossRefPubMed
35.
Orwoll E, Blank JB, Barrett-Connor E, Cauley J, Cummings S, Ensrud K, Lewis C, Cawthon PM, Marcus R, Marshall LM: Design and baseline characteristics of the osteoporotic fractures in men (MrOS) study--a large observational study of the determinants of fracture in older men. Contemp Clin Trials. 2005, 26 (5): 569-585. 10.1016/j.cct.2005.05.006.CrossRefPubMed
36.
Demirbag D, Ozdemir F, Ture M: Effects of coffee consumption and smoking habit on bone mineral density. Rheumatol Int. 2006, 26 (6): 530-535. 10.1007/s00296-005-0020-4.CrossRefPubMed
Metadata
Title
Risk factors of osteoporosis in healthy Moroccan men
Authors
Abdellah El Maghraoui
Merieme Ghazi
Salim Gassim
Imad Ghozlani
Aziza Mounach
Asmaa Rezqi
Mohamed Dehhaoui
Publication date
01-12-2010
Publisher
BioMed Central
Published in
BMC Musculoskeletal Disorders / Issue 1/2010
Electronic ISSN: 1471-2474
DOI
https://doi.org/10.1186/1471-2474-11-148

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