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Published in: BMC Pulmonary Medicine 1/2013

Open Access 01-12-2013 | Case report

A stone miner with both silicosis and constrictive pericarditis: case report and review of the literature

Authors: Yajian Jiang, Fangchun Shao

Published in: BMC Pulmonary Medicine | Issue 1/2013

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Abstract

Background

The working environment of stone miners has been believed to cause their susceptibility to respiratory diseases. Silicosis is an occupational disease caused by exposure to crystalline silica dust which is marked by inflammation and scarring in the lung. The immune system boosted after the silica invasion led to self-damage and lay the foundation of silicosis pathogenesis. Silicosis coexisting with other diseases in one patient has been reported, however, was not reported to coexist with constrictive pericarditis. We, for the first time, reported a patient with silicosis and constrictive pericarditis and thought the immune response was probably the link between the two.

Case presentation

A 59-year-old Chinese stone miner complained of chest distress was found to have lung nodules which were found to be silica deposits by biopsy. This patient was also found to have constrictive pericarditis at the same time. Later surgical decortication cured his symptoms.

Conclusion

We provided the first case having constrictive pericarditis concomitant with silicosis. A probable link between the two diseases was the immune response boosted by the silica deposits.
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Literature
1.
go back to reference Greenberg MI, Waksman J, Curtis J: Silicosis: a review. Dis Mon. 2007, 53: 394-416. 10.1016/j.disamonth.2007.09.020.CrossRefPubMed Greenberg MI, Waksman J, Curtis J: Silicosis: a review. Dis Mon. 2007, 53: 394-416. 10.1016/j.disamonth.2007.09.020.CrossRefPubMed
2.
go back to reference Santos C, Norte A, Fradinho F, Catarino A, Ferreira AJ, Loureiro M, Baganha MF: Silicosis - brief review and experience of a pulmonology ward. Rev Port Pneumol. 2010, 16: 99-115.CrossRefPubMed Santos C, Norte A, Fradinho F, Catarino A, Ferreira AJ, Loureiro M, Baganha MF: Silicosis - brief review and experience of a pulmonology ward. Rev Port Pneumol. 2010, 16: 99-115.CrossRefPubMed
3.
4.
go back to reference Dostert C, Petrilli V, Van Bruggen R, Steele C, Mossman BT, Tschopp J: Innate immune activation through Nalp3 inflammasome sensing of asbestos and silica. Science. 2008, 320: 674-677. 10.1126/science.1156995.CrossRefPubMedPubMedCentral Dostert C, Petrilli V, Van Bruggen R, Steele C, Mossman BT, Tschopp J: Innate immune activation through Nalp3 inflammasome sensing of asbestos and silica. Science. 2008, 320: 674-677. 10.1126/science.1156995.CrossRefPubMedPubMedCentral
5.
go back to reference Beamer CA, Migliaccio CT, Jessop F, Trapkus M, Yuan D, Holian A: Innate immune processes are sufficient for driving silicosis in mice. J Leukoc Biol. 2010, 88: 547-557. 10.1189/jlb.0210108.CrossRefPubMedPubMedCentral Beamer CA, Migliaccio CT, Jessop F, Trapkus M, Yuan D, Holian A: Innate immune processes are sufficient for driving silicosis in mice. J Leukoc Biol. 2010, 88: 547-557. 10.1189/jlb.0210108.CrossRefPubMedPubMedCentral
6.
7.
go back to reference Harrison J, Chen JQ, Miller W, Chen W, Hnizdo E, Lu J, Chisholm W, Keane M, Gao P, Wallace W: Risk of silicosis in cohorts of Chinese tin and tungsten miners and pottery workers (II): Workplace-specific silica particle surface composition. Am J Ind Med. 2005, 48: 10-15. 10.1002/ajim.20175.CrossRefPubMed Harrison J, Chen JQ, Miller W, Chen W, Hnizdo E, Lu J, Chisholm W, Keane M, Gao P, Wallace W: Risk of silicosis in cohorts of Chinese tin and tungsten miners and pottery workers (II): Workplace-specific silica particle surface composition. Am J Ind Med. 2005, 48: 10-15. 10.1002/ajim.20175.CrossRefPubMed
8.
go back to reference American thoracic society: Adverse effects of crystalline silica exposure. American thoracic society committee of the scientific assembly on environmental and occupational health. Am J Respir Crit Care Med. 1997, 155: 761-768.CrossRef American thoracic society: Adverse effects of crystalline silica exposure. American thoracic society committee of the scientific assembly on environmental and occupational health. Am J Respir Crit Care Med. 1997, 155: 761-768.CrossRef
9.
go back to reference Basu S, Stuckler D, Gonsalves G, Lurie M: The production of consumption: addressing the impact of mineral mining on tuberculosis in southern Africa. Global Health. 2009, 5: 11-10.1186/1744-8603-5-11.CrossRefPubMedPubMedCentral Basu S, Stuckler D, Gonsalves G, Lurie M: The production of consumption: addressing the impact of mineral mining on tuberculosis in southern Africa. Global Health. 2009, 5: 11-10.1186/1744-8603-5-11.CrossRefPubMedPubMedCentral
10.
go back to reference Leung CC, Yew WW, Law WS, Tam CM, Leung M, Chung YW, Cheung KW, Chan KW, Fu F: Smoking and tuberculosis among silicotic patients. Eur Respir J. 2007, 29: 745-750. 10.1183/09031936.00134706.CrossRefPubMed Leung CC, Yew WW, Law WS, Tam CM, Leung M, Chung YW, Cheung KW, Chan KW, Fu F: Smoking and tuberculosis among silicotic patients. Eur Respir J. 2007, 29: 745-750. 10.1183/09031936.00134706.CrossRefPubMed
11.
go back to reference Wilke RA, Salisbury S, Abdel-Rahman E, Brazy PC: Lupus-like autoimmune disease associated with silicosis. Nephrol Dial Transplant. 1996, 11: 1835-1838. 10.1093/oxfordjournals.ndt.a027678.CrossRefPubMed Wilke RA, Salisbury S, Abdel-Rahman E, Brazy PC: Lupus-like autoimmune disease associated with silicosis. Nephrol Dial Transplant. 1996, 11: 1835-1838. 10.1093/oxfordjournals.ndt.a027678.CrossRefPubMed
12.
go back to reference Kishimoto T, Tsuda K: A patient with asbestos-induced lung cancer complicated by silicosis. Ind Health. 2001, 39: 189-193. 10.2486/indhealth.39.189.CrossRefPubMed Kishimoto T, Tsuda K: A patient with asbestos-induced lung cancer complicated by silicosis. Ind Health. 2001, 39: 189-193. 10.2486/indhealth.39.189.CrossRefPubMed
13.
go back to reference Mohebbi I, Lameei A, Booshehri B, Aslanabadi N, Maasomi R, Dehghani M: Pericardial plaque: a unique complication of silicosis. Ind Health. 2011, 49: 122-125. 10.2486/indhealth.MS1145.CrossRefPubMed Mohebbi I, Lameei A, Booshehri B, Aslanabadi N, Maasomi R, Dehghani M: Pericardial plaque: a unique complication of silicosis. Ind Health. 2011, 49: 122-125. 10.2486/indhealth.MS1145.CrossRefPubMed
14.
go back to reference Cassel SL, Eisenbarth SC, Iyer SS, Sadler JJ, Colegio OR, Tephly LA, Carter AB, Rothman PB, Flavell RA, Sutterwala FS: The Nalp3 inflammasome is essential for the development of silicosis. Proc Natl Acad Sci U S A. 2008, 105: 9035-9040. 10.1073/pnas.0803933105.CrossRefPubMedPubMedCentral Cassel SL, Eisenbarth SC, Iyer SS, Sadler JJ, Colegio OR, Tephly LA, Carter AB, Rothman PB, Flavell RA, Sutterwala FS: The Nalp3 inflammasome is essential for the development of silicosis. Proc Natl Acad Sci U S A. 2008, 105: 9035-9040. 10.1073/pnas.0803933105.CrossRefPubMedPubMedCentral
15.
go back to reference Vallyathan V, Shi XL, Dalal NS, Irr W, Castranova V: Generation of free radicals from freshly fractured silica dust. Potential role in acute silica-induced lung injury. Am Rev Respir Dis. 1988, 138: 1213-1219. 10.1164/ajrccm/138.5.1213.CrossRefPubMed Vallyathan V, Shi XL, Dalal NS, Irr W, Castranova V: Generation of free radicals from freshly fractured silica dust. Potential role in acute silica-induced lung injury. Am Rev Respir Dis. 1988, 138: 1213-1219. 10.1164/ajrccm/138.5.1213.CrossRefPubMed
16.
go back to reference Chen W, Hnizdo E, Chen JQ, Attfield MD, Gao P, Hearl F, Lu J, Wallace WE: Risk of silicosis in cohorts of Chinese tin and tungsten miners, and pottery workers (I): an epidemiological study. Am J Ind Med. 2005, 48: 1-9. 10.1002/ajim.20174.CrossRefPubMed Chen W, Hnizdo E, Chen JQ, Attfield MD, Gao P, Hearl F, Lu J, Wallace WE: Risk of silicosis in cohorts of Chinese tin and tungsten miners, and pottery workers (I): an epidemiological study. Am J Ind Med. 2005, 48: 1-9. 10.1002/ajim.20174.CrossRefPubMed
17.
go back to reference Khandaker MH, Espinosa RE, Nishimura RA, Sinak LJ, Hayes SN, Melduni RM, Oh JK: Pericardial disease: diagnosis and management. Mayo Clin Proc. 2010, 85: 572-593. 10.4065/mcp.2010.0046.CrossRefPubMedPubMedCentral Khandaker MH, Espinosa RE, Nishimura RA, Sinak LJ, Hayes SN, Melduni RM, Oh JK: Pericardial disease: diagnosis and management. Mayo Clin Proc. 2010, 85: 572-593. 10.4065/mcp.2010.0046.CrossRefPubMedPubMedCentral
Metadata
Title
A stone miner with both silicosis and constrictive pericarditis: case report and review of the literature
Authors
Yajian Jiang
Fangchun Shao
Publication date
01-12-2013
Publisher
BioMed Central
Published in
BMC Pulmonary Medicine / Issue 1/2013
Electronic ISSN: 1471-2466
DOI
https://doi.org/10.1186/1471-2466-13-71

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