Skip to main content
Top
Published in: BMC Public Health 1/2004

Open Access 01-12-2004 | Research article

Vitamin D deficiency and causative factors in the population of Tehran

Authors: Sima Hashemipour, Bagher Larijani, Hossein Adibi, Ebrahim Javadi, Mojtaba Sedaghat, Mohammad Pajouhi, Akbar Soltani, Ali Reza Shafaei, Zohreh Hamidi, Ali Reza Khalili Fard, Arash Hossein-Nezhad, Fargol Booya

Published in: BMC Public Health | Issue 1/2004

Login to get access

Abstract

Background

There are multiple studies in different countries regarding the prevalence of vitamin D deficiency. These studies showed high prevalence of vitamin D deficiency in Asian countries. This study tries to elucidate the prevalence of vitamin D deficiency and its influencing factors in population of Tehran.

Methods

1210 subjects 20–64 years old were randomly selected. 25 (OH) D serum levels were measured. Duration of exposure to sunlight, the type of clothing and level of calcium intake and BMI were quantified based on a questionnaire.

Results

A high percentage of vitamin D deficiency was defined in the study population. Prevalence of severe, moderate and mild Vitamin D deficiency was 9.5%, 57.6% and 14.2% respectively. Vitamin D serum levels had no significant statistical relation with the duration of exposure to sunlight, kind of clothing and BMI. Calcium intake in the normal vitamin D group was significantly higher than the other groups (714.67 ± 330.8 mg/day vs 503.39 ± 303.1, 577.93 ± 304.9,595.84 ± 313.6). Vitamin D serum levels in young and middle aged females were significantly lower than the older group.

Conclusions

Vitamin D deficiency has a high prevalence in Tehran. In order to avoid complications of vitamin D deficiency, supplemental dietary intake seems essential.
Appendix
Available only for authorised users
Literature
1.
go back to reference Parfitt AM, Gallagher JC, Heaney RP, Johnston CC, Neer R, Whedon GD: Vitamin D and bone health in the elderly. Am J Clin Nutr. 1982, Suppl 5: 1014-1031. Parfitt AM, Gallagher JC, Heaney RP, Johnston CC, Neer R, Whedon GD: Vitamin D and bone health in the elderly. Am J Clin Nutr. 1982, Suppl 5: 1014-1031.
2.
go back to reference Peacoak M: Effect of calcium and vitamin D insufficiency on the skeleton. Osteoporos Int. 1998, Suppl 8: S45-S51.CrossRef Peacoak M: Effect of calcium and vitamin D insufficiency on the skeleton. Osteoporos Int. 1998, Suppl 8: S45-S51.CrossRef
3.
go back to reference Deluca HF: The Vitamin D Story: a Collaborative effort of basic science and clinical medicine. FASEB. 1988, 2: 224-236. Deluca HF: The Vitamin D Story: a Collaborative effort of basic science and clinical medicine. FASEB. 1988, 2: 224-236.
4.
go back to reference Bouillon R: Vitamin D: Photosynthesis, metabolism, and action to clinical applications. In Endocrinology. Edited by: Degroot L, Jameson JL, Burger HG. 2001, Philadelphia: WB Saunders, 1009-1028. 3 Bouillon R: Vitamin D: Photosynthesis, metabolism, and action to clinical applications. In Endocrinology. Edited by: Degroot L, Jameson JL, Burger HG. 2001, Philadelphia: WB Saunders, 1009-1028. 3
5.
go back to reference Bouillon R, Carmeliet G, Daci E, et al: Vitamin D Metabolism and action. Osteoporos Int. 1998, Suppl 2: S13-19.CrossRef Bouillon R, Carmeliet G, Daci E, et al: Vitamin D Metabolism and action. Osteoporos Int. 1998, Suppl 2: S13-19.CrossRef
6.
go back to reference Du X, Greenfield H, Fraser DR, et al: Vitamin D deficiency and associated factors in adolescent girl in Beijing. Am J Clin Nutr. 2001, 74: 494-500.PubMed Du X, Greenfield H, Fraser DR, et al: Vitamin D deficiency and associated factors in adolescent girl in Beijing. Am J Clin Nutr. 2001, 74: 494-500.PubMed
7.
go back to reference Alagol F, Shihadeh Y, Boztepe H, et al: Sunlight exposure and vitamin D in Turkish women. J Endocrinol Invest. 2000, 23: 173-177.CrossRefPubMed Alagol F, Shihadeh Y, Boztepe H, et al: Sunlight exposure and vitamin D in Turkish women. J Endocrinol Invest. 2000, 23: 173-177.CrossRefPubMed
8.
go back to reference Dawodu A, Agarwal M, Hossain M, et al: Hypervitaminosis D and vitamin D deficiency in exclusively brest feeding infants and their mother in summer :a justification for vitamin D supplementation of brest-feeding infants. J Pediatr. 2003, 142: 169-173. 10.1067/mpd.2003.63.CrossRefPubMed Dawodu A, Agarwal M, Hossain M, et al: Hypervitaminosis D and vitamin D deficiency in exclusively brest feeding infants and their mother in summer :a justification for vitamin D supplementation of brest-feeding infants. J Pediatr. 2003, 142: 169-173. 10.1067/mpd.2003.63.CrossRefPubMed
9.
go back to reference Sedrani SH: Low 25-Hydroxy vitamin D and normal serum calcium concentrations in Saudi Arabia: Riyadh region. Ann Nutr Metab. 1984, 28: 181-185.CrossRefPubMed Sedrani SH: Low 25-Hydroxy vitamin D and normal serum calcium concentrations in Saudi Arabia: Riyadh region. Ann Nutr Metab. 1984, 28: 181-185.CrossRefPubMed
10.
go back to reference Sedrani SH, Elidrissy AW, Arabi KM: Sunlight and vitamin D status in normal Saudi subjects. Am J Clin Nutr. 1983, 38: 129-132.PubMed Sedrani SH, Elidrissy AW, Arabi KM: Sunlight and vitamin D status in normal Saudi subjects. Am J Clin Nutr. 1983, 38: 129-132.PubMed
11.
go back to reference Azizi F, Rais-Zadeh F, Mir Said Ghazi A: vitamin D deficiency in a group of Tehran Population. Research In Medicine. 2000, 4: 291-303. Azizi F, Rais-Zadeh F, Mir Said Ghazi A: vitamin D deficiency in a group of Tehran Population. Research In Medicine. 2000, 4: 291-303.
12.
go back to reference Taha S, Dost S, Sedrani S: 25-hydroxy vitamin D and total calcium extra ordinarily low plasma concentrations in Saudi mothers and their neonates. Pediatr Res. 1984, 18: 739-741.CrossRefPubMed Taha S, Dost S, Sedrani S: 25-hydroxy vitamin D and total calcium extra ordinarily low plasma concentrations in Saudi mothers and their neonates. Pediatr Res. 1984, 18: 739-741.CrossRefPubMed
13.
14.
go back to reference Gowami R, Gupta N, Gosuwami D, et al: Prevalence and significance of low 25-Hydroxy vitamin D concentrations in healthy subjects in Dehli. Am J Clin Nutr. 2000, 72: 422-475. Gowami R, Gupta N, Gosuwami D, et al: Prevalence and significance of low 25-Hydroxy vitamin D concentrations in healthy subjects in Dehli. Am J Clin Nutr. 2000, 72: 422-475.
15.
go back to reference Lips P: Vitamin D deficiency and secondary hyperparathyroidism in the elderly: Consequences for bone loss and fractures and therapeutic implications. Endocr Rev. 2001, 22: 477-501. 10.1210/er.22.4.477.CrossRefPubMed Lips P: Vitamin D deficiency and secondary hyperparathyroidism in the elderly: Consequences for bone loss and fractures and therapeutic implications. Endocr Rev. 2001, 22: 477-501. 10.1210/er.22.4.477.CrossRefPubMed
16.
go back to reference Omdahl JL, Garry PJ, Hunsaker LA, et al: Nutritional status in a healthy elderly population: vitamin D. Am J Clin Nutr. 1982, 36: 1225-1232.PubMed Omdahl JL, Garry PJ, Hunsaker LA, et al: Nutritional status in a healthy elderly population: vitamin D. Am J Clin Nutr. 1982, 36: 1225-1232.PubMed
17.
go back to reference Kinyamu HK, Gallagher JC, Balhorn KE, et al: Serum vitamin D metabolites and calcium absorpation in normal young and elderly free – living women and in women living in nursing homes. Am J clin Nutr. 1997, 65: 790-797.PubMed Kinyamu HK, Gallagher JC, Balhorn KE, et al: Serum vitamin D metabolites and calcium absorpation in normal young and elderly free – living women and in women living in nursing homes. Am J clin Nutr. 1997, 65: 790-797.PubMed
18.
go back to reference Burnard B, Sloutskis D, Gianoli F, et al: Serum 25-Hydroxy vitamin D: distribution and determinants in the Swiss population. Am J Clin Nutr. 1992, 56: 537-542. Burnard B, Sloutskis D, Gianoli F, et al: Serum 25-Hydroxy vitamin D: distribution and determinants in the Swiss population. Am J Clin Nutr. 1992, 56: 537-542.
19.
go back to reference Chapuy MC, Preziosi P, Maamer M, et al: Prevalence of vitamin D insufficiency in on adult normal population. Osteopros Int. 1997, 7: 439-443. 10.1007/s001980050030.CrossRef Chapuy MC, Preziosi P, Maamer M, et al: Prevalence of vitamin D insufficiency in on adult normal population. Osteopros Int. 1997, 7: 439-443. 10.1007/s001980050030.CrossRef
20.
go back to reference Scharla SH, Scheidt Nave C: Reference range of 25-Hydroxys vitamin D serum concentrations in Germany. Clin Lab. 1996, 42: 475-477. Scharla SH, Scheidt Nave C: Reference range of 25-Hydroxys vitamin D serum concentrations in Germany. Clin Lab. 1996, 42: 475-477.
21.
go back to reference Vander Wielen RP, Lowik MR, Vanden Berg H, et al: Serum vitamin D concentrations among elderly people in Europe. Lancet. 1995, 346: 207-210. 10.1016/S0140-6736(95)91266-5.CrossRef Vander Wielen RP, Lowik MR, Vanden Berg H, et al: Serum vitamin D concentrations among elderly people in Europe. Lancet. 1995, 346: 207-210. 10.1016/S0140-6736(95)91266-5.CrossRef
22.
go back to reference Souberbielle JC, Cormier C, Kindermans C, et al: Vitamin D status and redefining serum parathyroid hormone reference range in the elderly. J clin Endocrinol Metab. 2001, 86: 3086-3090. 10.1210/jc.86.7.3086.PubMed Souberbielle JC, Cormier C, Kindermans C, et al: Vitamin D status and redefining serum parathyroid hormone reference range in the elderly. J clin Endocrinol Metab. 2001, 86: 3086-3090. 10.1210/jc.86.7.3086.PubMed
23.
go back to reference Bettica P, Bevilacqua M, Vago T, Norbiato G: High prevalence of hypovitaminosis among free living postmenopausal women referred to an osteoporos outpatient clinic in northern Italy for initial screening. Osteoporosis Int. 1999, 9: 226-229. 10.1007/s001980050141.CrossRef Bettica P, Bevilacqua M, Vago T, Norbiato G: High prevalence of hypovitaminosis among free living postmenopausal women referred to an osteoporos outpatient clinic in northern Italy for initial screening. Osteoporosis Int. 1999, 9: 226-229. 10.1007/s001980050141.CrossRef
24.
go back to reference Finch PJ, Ang L, Colston KW, et al: Blunted Seasonal variation in serum 25-hydroxy vitamin D and increased risk of osteomalacia in vegetarian London Asians. Eur J clin Nutr. 1992, 46: 509-515.PubMed Finch PJ, Ang L, Colston KW, et al: Blunted Seasonal variation in serum 25-hydroxy vitamin D and increased risk of osteomalacia in vegetarian London Asians. Eur J clin Nutr. 1992, 46: 509-515.PubMed
25.
go back to reference Goel KM, Sweet EM, Logan RW, et al: Florid and subclinical rickets among immigrant children in Glasgow. Lancet. 1976, 1: 1141-1145. 10.1016/S0140-6736(76)91538-5.CrossRefPubMed Goel KM, Sweet EM, Logan RW, et al: Florid and subclinical rickets among immigrant children in Glasgow. Lancet. 1976, 1: 1141-1145. 10.1016/S0140-6736(76)91538-5.CrossRefPubMed
26.
go back to reference Reinhold JG: Rickets in Asian immigrants. Lancet. 1976, 2: 1132-1133. 10.1016/S0140-6736(76)92673-8.CrossRefPubMed Reinhold JG: Rickets in Asian immigrants. Lancet. 1976, 2: 1132-1133. 10.1016/S0140-6736(76)92673-8.CrossRefPubMed
27.
go back to reference Smith R: Asian rickets and osteomalacia. Q J Med. 1990, 76: 899-901.PubMed Smith R: Asian rickets and osteomalacia. Q J Med. 1990, 76: 899-901.PubMed
28.
go back to reference National statistics directory book.. Iran Statistics Center: Number in publications of statistics center. 2001, 3589- National statistics directory book.. Iran Statistics Center: Number in publications of statistics center. 2001, 3589-
29.
go back to reference Lo CW, Paris PW, Holick MF, et al: Indian and Pakistani immigrants have the same capacity as Caucasians to produce vitamin D in response to ultra violet irradiation. Am J Clin Nutr. 1986, 44: 683-685.PubMed Lo CW, Paris PW, Holick MF, et al: Indian and Pakistani immigrants have the same capacity as Caucasians to produce vitamin D in response to ultra violet irradiation. Am J Clin Nutr. 1986, 44: 683-685.PubMed
31.
go back to reference Awumey EM, Mitra DA, Hollis BW, et al: Vitamin D metabolism is altered in Asian Indians in the southern United States: a clinical research study. J Clin Endocrinol Metab. 1998, 83: 169-173. 10.1210/jc.83.1.169.PubMed Awumey EM, Mitra DA, Hollis BW, et al: Vitamin D metabolism is altered in Asian Indians in the southern United States: a clinical research study. J Clin Endocrinol Metab. 1998, 83: 169-173. 10.1210/jc.83.1.169.PubMed
Metadata
Title
Vitamin D deficiency and causative factors in the population of Tehran
Authors
Sima Hashemipour
Bagher Larijani
Hossein Adibi
Ebrahim Javadi
Mojtaba Sedaghat
Mohammad Pajouhi
Akbar Soltani
Ali Reza Shafaei
Zohreh Hamidi
Ali Reza Khalili Fard
Arash Hossein-Nezhad
Fargol Booya
Publication date
01-12-2004
Publisher
BioMed Central
Published in
BMC Public Health / Issue 1/2004
Electronic ISSN: 1471-2458
DOI
https://doi.org/10.1186/1471-2458-4-38

Other articles of this Issue 1/2004

BMC Public Health 1/2004 Go to the issue