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Published in: BMC Public Health 1/2013

Open Access 01-12-2013 | Research article

A cross-sectional assessment of knowledge, attitude and practice among Hepatitis-B patients in Quetta, Pakistan

Authors: Noman ul Haq, Mohamed Azmi Hassali, Asrul Akmal Shafie, Fahad Saleem, Maryam Farooqui, Abdul Haseeb, Hisham Aljadhey

Published in: BMC Public Health | Issue 1/2013

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Abstract

Background

Hepatitis-B is a life threatening infection resulting in 0.6 million deaths annually. The prevalence of Hepatitis-B is rising in Pakistan and furthermore, there is paucity of information about Knowledge, Attitude and Practice among Hepatitis-B patients. Better disease related knowledge is important to have positive attitude and that will bring the good practices which will prevent the further spread of infection. This study aimed to evaluate knowledge, attitude and practice of Hepatitis-B Patients in Quetta city, Pakistan.

Methods

A cross-sectional, descriptive study was undertaken with 390 Hepatitis-B patients attending two public hospitals in Quetta city, Pakistan. Knowledge, attitude and practice regarding Hepatitis-B were assessed using a pre-validated questionnaire containing 20, 7 and 8 questions for knowledge, attitude and practice, respectively. Descriptive statistics were used for elaborating patients’ demographic characteristics and mean scores for knowledge, attitude and practice of Hepatitis-B patients. Inferential statistics (Mann–Whitney U test and Kruskal Wallis tests, p < 0.05) were used to establish association between study variables. Spearman’s rho correlation was used to identify the association between the knowledge, attitude and practice scores.

Results

Out of 390 patients, 223 (57.2%) were males, with the majority (136, 34.9%) in the age group of 38–47 years. Mean age of the study cohort was 32.6 ± 9.5 years. One hundred and four (26.7%) had primary level education, with 110 (28.2%) working in the private sector. The mean scores for knowledge, attitude and practice were 8.48 ± 2.7, 3.87 ± 1.2 and 2.37 ± 1.0, respectively. Education, locality and occupation were significantly associated with knowledge, attitude and practice scores. Significant positive linear correlations between knowledge-attitude (r = 0.466, p < 0.01) knowledge-practice (r = 0.221, p < 0.01) and attitude-practice (r = 0.224, p < 0.01) were also observed from the study results.

Conclusion

The findings of this study indicate that Hepatitis-B patients lack a basic understanding of infection control and management. This can result in the further spread of Hepatitis-B infection. Extensive health education campaigns should be provided to the patients in the hospital as well as in community settings for rational control and management of the disease.
Literature
2.
go back to reference Lee WM: Hepatitis B virus infection. N Engl J Med. 1997, 337 (24): 1733-1745. 10.1056/NEJM199712113372406.CrossRefPubMed Lee WM: Hepatitis B virus infection. N Engl J Med. 1997, 337 (24): 1733-1745. 10.1056/NEJM199712113372406.CrossRefPubMed
3.
4.
go back to reference Keeffe EB, Dieterich DT, Han SHB, Jacobson IM, Martin P, Schiff ER, Tobias H: A treatment algorithm for the management of chronic hepatitis B virus infection in the United States: 2008 update. Clin Gastroenterol Hepatol. 2008, 6 (12): 1315-1341. 10.1016/j.cgh.2008.08.021.CrossRefPubMed Keeffe EB, Dieterich DT, Han SHB, Jacobson IM, Martin P, Schiff ER, Tobias H: A treatment algorithm for the management of chronic hepatitis B virus infection in the United States: 2008 update. Clin Gastroenterol Hepatol. 2008, 6 (12): 1315-1341. 10.1016/j.cgh.2008.08.021.CrossRefPubMed
5.
go back to reference Mahoney FJ: Update on diagnosis, management, and prevention of hepatitis B virus infection. Clin Microbiol Rev. 1999, 12 (2): 351-366.PubMedPubMedCentral Mahoney FJ: Update on diagnosis, management, and prevention of hepatitis B virus infection. Clin Microbiol Rev. 1999, 12 (2): 351-366.PubMedPubMedCentral
6.
go back to reference André F: Hepatitis B epidemiology in Asia, the middle East and Africa. Vaccine. 2000, 18: S20-S22.CrossRefPubMed André F: Hepatitis B epidemiology in Asia, the middle East and Africa. Vaccine. 2000, 18: S20-S22.CrossRefPubMed
7.
go back to reference Lesmana LA, Leung NWY, Mahachai V, Phiet PH, Suh DJ, Yao G, Zhuang H: Hepatitis B: overview of the burden of disease in the Asia Pacific region. Liver Int. 2006, 26 (S2): 3-10. 10.1111/j.1478-3231.2006.01370.x.CrossRef Lesmana LA, Leung NWY, Mahachai V, Phiet PH, Suh DJ, Yao G, Zhuang H: Hepatitis B: overview of the burden of disease in the Asia Pacific region. Liver Int. 2006, 26 (S2): 3-10. 10.1111/j.1478-3231.2006.01370.x.CrossRef
8.
go back to reference Mohamed R, Desmond P, Suh DJ, Amarapurkar D, Gane E, Guangbi Y, Hou JL, Jafri W, Lai CL, Lee CH: Practical difficulties in the management of hepatitis B in the Asia–Pacific region. J Gastroenterol Hepatol. 2004, 19 (9): 958-969. 10.1111/j.1440-1746.2004.03420.x.CrossRefPubMed Mohamed R, Desmond P, Suh DJ, Amarapurkar D, Gane E, Guangbi Y, Hou JL, Jafri W, Lai CL, Lee CH: Practical difficulties in the management of hepatitis B in the Asia–Pacific region. J Gastroenterol Hepatol. 2004, 19 (9): 958-969. 10.1111/j.1440-1746.2004.03420.x.CrossRefPubMed
9.
go back to reference Kumar A, Lalani S, Afridi A, Khuwaja A: Screening of hepatitis B and C among people visiting general practice clinics in a rural district of Sindh. Pakistan. J Ayub Med Coll Abbottabad. 2010, 22 (4): 143-PubMed Kumar A, Lalani S, Afridi A, Khuwaja A: Screening of hepatitis B and C among people visiting general practice clinics in a rural district of Sindh. Pakistan. J Ayub Med Coll Abbottabad. 2010, 22 (4): 143-PubMed
10.
go back to reference Abdul MS, Jamal Q, Khanani R, Iqbal N, Kaher S: Prevalence of hepatitis B surface antigen and HCV antibodies in hepatocellular carcinoma cases in Karachi. Pakistan. Trop Doct. 1997, 27 (1): 45- Abdul MS, Jamal Q, Khanani R, Iqbal N, Kaher S: Prevalence of hepatitis B surface antigen and HCV antibodies in hepatocellular carcinoma cases in Karachi. Pakistan. Trop Doct. 1997, 27 (1): 45-
11.
go back to reference Agboatwalla M, Isomura S, Miyake K, Yamashita T, Morishita T, Akram DS: Hepatitis A, B and C seroprevalence in Pakistan. Indian J Pediatr. 1994, 61 (5): 545-549. 10.1007/BF02751716.CrossRefPubMed Agboatwalla M, Isomura S, Miyake K, Yamashita T, Morishita T, Akram DS: Hepatitis A, B and C seroprevalence in Pakistan. Indian J Pediatr. 1994, 61 (5): 545-549. 10.1007/BF02751716.CrossRefPubMed
12.
go back to reference Jafri W, Jafri N, Yakoob J, Islam M, Tirmizi SFA, Jafar T, Akhtar S, Hamid S, Shah H, Nizami S: Hepatitis B and C: prevalence and risk factors associated with seropositivity among children in Karachi. Pakistan. BMC Infect Dis. 2006, 6 (1): 101-10.1186/1471-2334-6-101.CrossRefPubMed Jafri W, Jafri N, Yakoob J, Islam M, Tirmizi SFA, Jafar T, Akhtar S, Hamid S, Shah H, Nizami S: Hepatitis B and C: prevalence and risk factors associated with seropositivity among children in Karachi. Pakistan. BMC Infect Dis. 2006, 6 (1): 101-10.1186/1471-2334-6-101.CrossRefPubMed
13.
go back to reference Khattak M, Salamat N, Bhatti F, Qureshi T: Seroprevalence of hepatitis B, C and HIV in blood donors in northern Pakistan. J Pak Med Assoc. 2002, 52 (9): 398-402.PubMed Khattak M, Salamat N, Bhatti F, Qureshi T: Seroprevalence of hepatitis B, C and HIV in blood donors in northern Pakistan. J Pak Med Assoc. 2002, 52 (9): 398-402.PubMed
14.
go back to reference Khokhar N, Gill ML, Malik GJ: General seroprevalence of hepatitis C and hepatitis B virus infections in population. J Coll Physicians Surg Pak. 2004, 14 (9): 534-PubMed Khokhar N, Gill ML, Malik GJ: General seroprevalence of hepatitis C and hepatitis B virus infections in population. J Coll Physicians Surg Pak. 2004, 14 (9): 534-PubMed
15.
go back to reference Launiala A: How much can a KAP survey tell us about people’s knowledge, attitudes and practices? Some observations from medical anthropology research on malaria in pregnancy in Malawi. Anthropology Matters Journal. 2009, 11 (1): 1-13. Launiala A: How much can a KAP survey tell us about people’s knowledge, attitudes and practices? Some observations from medical anthropology research on malaria in pregnancy in Malawi. Anthropology Matters Journal. 2009, 11 (1): 1-13.
17.
go back to reference Good B: Medicine, rationality, and experience: an anthropological perspective. 1994, Cambridge: Cambridge Univ Pr Good B: Medicine, rationality, and experience: an anthropological perspective. 1994, Cambridge: Cambridge Univ Pr
18.
go back to reference Tannahill A: Beyond evidence—to ethics: a decision-making framework for health promotion, public health and health improvement. Health Promot Int. 2008, 23 (4): 380-390. 10.1093/heapro/dan032.CrossRefPubMed Tannahill A: Beyond evidence—to ethics: a decision-making framework for health promotion, public health and health improvement. Health Promot Int. 2008, 23 (4): 380-390. 10.1093/heapro/dan032.CrossRefPubMed
19.
go back to reference Ribeaux P, Poppleton SE: Psychology and Work. 1978, Macmillan London: an introduction Ribeaux P, Poppleton SE: Psychology and Work. 1978, Macmillan London: an introduction
20.
go back to reference Yoder PS: Negotiating relevance: belief, knowledge, and practice in international health projects. Med Anthropol Q. 1997, 11 (2): 131-146. 10.1525/maq.1997.11.2.131.CrossRefPubMed Yoder PS: Negotiating relevance: belief, knowledge, and practice in international health projects. Med Anthropol Q. 1997, 11 (2): 131-146. 10.1525/maq.1997.11.2.131.CrossRefPubMed
21.
go back to reference Haq NU, Hassali MA, Shafie AA, Saleem F, Farooqui M, Aljadhey H: A cross sectional assessment of knowledge, attitude and practice towards Hepatitis B among healthy population of Quetta. Pakistan. BMC Public Health. 2012, 12 (1): 692-10.1186/1471-2458-12-692.CrossRef Haq NU, Hassali MA, Shafie AA, Saleem F, Farooqui M, Aljadhey H: A cross sectional assessment of knowledge, attitude and practice towards Hepatitis B among healthy population of Quetta. Pakistan. BMC Public Health. 2012, 12 (1): 692-10.1186/1471-2458-12-692.CrossRef
22.
go back to reference Anwar M, Green J, Norris P: Health-seeking behaviour in Pakistan: A narrative review of the existing literature. Public Health. 2012, 126 (6): 507-517. 10.1016/j.puhe.2012.02.006.CrossRefPubMed Anwar M, Green J, Norris P: Health-seeking behaviour in Pakistan: A narrative review of the existing literature. Public Health. 2012, 126 (6): 507-517. 10.1016/j.puhe.2012.02.006.CrossRefPubMed
23.
go back to reference Vandenbroucke JP, Von Elm E, Altman DG, Gotzsche PC, Mulrow CD, Pocock SJ, Poole C, Schlesselman JJ, Egger M: Strengthening the Reporting of Observational Studies in Epidemiology (STROBE): explanation and elaboration. PLoS Med. 2007, 4 (10): e297-10.1371/journal.pmed.0040297.CrossRefPubMedPubMedCentral Vandenbroucke JP, Von Elm E, Altman DG, Gotzsche PC, Mulrow CD, Pocock SJ, Poole C, Schlesselman JJ, Egger M: Strengthening the Reporting of Observational Studies in Epidemiology (STROBE): explanation and elaboration. PLoS Med. 2007, 4 (10): e297-10.1371/journal.pmed.0040297.CrossRefPubMedPubMedCentral
24.
go back to reference Daniel WW: Biostatistics: Basic concepts and methodology for the health sciences. 2010, John Wiley & Sons Daniel WW: Biostatistics: Basic concepts and methodology for the health sciences. 2010, John Wiley & Sons
25.
go back to reference Volicer BJ: Biostatistics: A Foundation for Analysis in the Health Sciences. Nurs Res. 1979, 28 (5): 266-10.1097/00006199-197909000-00003.CrossRef Volicer BJ: Biostatistics: A Foundation for Analysis in the Health Sciences. Nurs Res. 1979, 28 (5): 266-10.1097/00006199-197909000-00003.CrossRef
27.
go back to reference Alam M, Tariq W: Knowledge, attitudes and practices about hepatitis B and C among young healthy males. Pak J Pathol. 2006, 17 (4): 147-150. Alam M, Tariq W: Knowledge, attitudes and practices about hepatitis B and C among young healthy males. Pak J Pathol. 2006, 17 (4): 147-150.
28.
go back to reference Behling O, Law KS: Translating questionnaires and other research instruments. 2000, Sage Publications, Inc: Problems and solutionsCrossRef Behling O, Law KS: Translating questionnaires and other research instruments. 2000, Sage Publications, Inc: Problems and solutionsCrossRef
29.
go back to reference Harkness JA, Schoua-Glusberg A: Questionnaires in translation. ZUMA-Nachrichten Spezial. 1998, 3: 87-127. Harkness JA, Schoua-Glusberg A: Questionnaires in translation. ZUMA-Nachrichten Spezial. 1998, 3: 87-127.
30.
go back to reference Santos JRA: Cronbach’s alpha: A tool for assessing the reliability of scales. J Extension. 1999, 37 (2): 1-5. Santos JRA: Cronbach’s alpha: A tool for assessing the reliability of scales. J Extension. 1999, 37 (2): 1-5.
31.
go back to reference Mundrom D, Perret J, Schaffer J, Piccone A, Roozeboom M: Bonferroni adjustments in tests for regression coefficients. Multiple Linear Regression Viewpoints. 2006, 32 (1): 1-6. Mundrom D, Perret J, Schaffer J, Piccone A, Roozeboom M: Bonferroni adjustments in tests for regression coefficients. Multiple Linear Regression Viewpoints. 2006, 32 (1): 1-6.
32.
go back to reference Haider G, Haider A: Awareness of women regarding hepatitis B. J Ayub Med Coll Abbottabad. 2008, 20 (4): Haider G, Haider A: Awareness of women regarding hepatitis B. J Ayub Med Coll Abbottabad. 2008, 20 (4):
33.
go back to reference Nguyen TT, Taylor V, Bastani R, Maxwell AE, Mcphee SJ: Hepatitis B awareness, knowledge, and screening among Asian Americans. J Cancer Educ. 2007, 22 (4): 266-272. 10.1007/BF03174128.CrossRefPubMed Nguyen TT, Taylor V, Bastani R, Maxwell AE, Mcphee SJ: Hepatitis B awareness, knowledge, and screening among Asian Americans. J Cancer Educ. 2007, 22 (4): 266-272. 10.1007/BF03174128.CrossRefPubMed
34.
go back to reference Taylor VM, Tu SP, Woodall E, Acorda E, Chen H, Choe J, Li L, Yasui Y, Hislop TG: Hepatitis B knowledge and practices among Chinese immigrants to the United States. Asian Pac J Cancer Prev. 2006, 7 (2): 313-317.PubMed Taylor VM, Tu SP, Woodall E, Acorda E, Chen H, Choe J, Li L, Yasui Y, Hislop TG: Hepatitis B knowledge and practices among Chinese immigrants to the United States. Asian Pac J Cancer Prev. 2006, 7 (2): 313-317.PubMed
35.
go back to reference Thompson MJ, Taylor VM, Jackson JC, Yasui Y, Kuniyuki A: Shin‒Ping T, Hislop TG: Hepatitis B knowledge and practices among Chinese American women in Seattle. Washington. J Cancer Educ. 2002, 17 (4): 222-226.PubMed Thompson MJ, Taylor VM, Jackson JC, Yasui Y, Kuniyuki A: Shin‒Ping T, Hislop TG: Hepatitis B knowledge and practices among Chinese American women in Seattle. Washington. J Cancer Educ. 2002, 17 (4): 222-226.PubMed
36.
go back to reference van der Veen YJJ, Voeten HACM, de Zwart O, Richardus JH: Awareness, knowledge and self-reported test rates regarding Hepatitis B in Turkish-Dutch: a survey. BMC Public Health. 2010, 10 (1): 512-10.1186/1471-2458-10-512.CrossRefPubMedPubMedCentral van der Veen YJJ, Voeten HACM, de Zwart O, Richardus JH: Awareness, knowledge and self-reported test rates regarding Hepatitis B in Turkish-Dutch: a survey. BMC Public Health. 2010, 10 (1): 512-10.1186/1471-2458-10-512.CrossRefPubMedPubMedCentral
37.
go back to reference Wu CA, Lin SY, So SK, Chang ET: Hepatitis B and liver cancer knowledge and preventive practices among Asian Americans in the San Francisco Bay Area. California. Asian Pac J Cancer Prev. 2007, 8 (1): 127-134.PubMed Wu CA, Lin SY, So SK, Chang ET: Hepatitis B and liver cancer knowledge and preventive practices among Asian Americans in the San Francisco Bay Area. California. Asian Pac J Cancer Prev. 2007, 8 (1): 127-134.PubMed
38.
go back to reference Becker MH: The Health Belief Model and Sick Role Behavior. Health Educ Behav. 1974, 2 (4): 409-419.CrossRef Becker MH: The Health Belief Model and Sick Role Behavior. Health Educ Behav. 1974, 2 (4): 409-419.CrossRef
39.
go back to reference Shaikh BT, Haran D, Hatcher J: Where do they go, whom do they consult, and why? Health-seeking behaviors in the northern areas of Pakistan. Qual Health Res. 2008, 18 (6): 747-755. 10.1177/1049732308317220.CrossRefPubMed Shaikh BT, Haran D, Hatcher J: Where do they go, whom do they consult, and why? Health-seeking behaviors in the northern areas of Pakistan. Qual Health Res. 2008, 18 (6): 747-755. 10.1177/1049732308317220.CrossRefPubMed
40.
go back to reference Ul Haq N, Hassali MA, Shafie AA, Saleem F, Aljadhey H: A cross sectional assessment of health related quality of life among patients with Hepatitis-B in Pakistan. Health Qual Life Outcomes. 2012, 10 (1): 91-10.1186/1477-7525-10-91.CrossRefPubMedPubMedCentral Ul Haq N, Hassali MA, Shafie AA, Saleem F, Aljadhey H: A cross sectional assessment of health related quality of life among patients with Hepatitis-B in Pakistan. Health Qual Life Outcomes. 2012, 10 (1): 91-10.1186/1477-7525-10-91.CrossRefPubMedPubMedCentral
41.
go back to reference Cheung J, Lee TK, Teh CZ, Wang C, Kwan W, Yoshida EM: Cross-sectional study of hepatitis B awareness among Chinese and Southeast Asian Canadians in the Vancouver-Richmond community. Can J Gastroenterol. 2005, 19 (4): 245-249.CrossRefPubMed Cheung J, Lee TK, Teh CZ, Wang C, Kwan W, Yoshida EM: Cross-sectional study of hepatitis B awareness among Chinese and Southeast Asian Canadians in the Vancouver-Richmond community. Can J Gastroenterol. 2005, 19 (4): 245-249.CrossRefPubMed
42.
go back to reference Singh A, Purohit B: Knowledge, Attitude and Practice towards Infection Control Measures and it’s Correlation among Dental Students in Bhopal city. Central India. Int J Infect Control. 2010, 7 (1): 1-9. Singh A, Purohit B: Knowledge, Attitude and Practice towards Infection Control Measures and it’s Correlation among Dental Students in Bhopal city. Central India. Int J Infect Control. 2010, 7 (1): 1-9.
43.
go back to reference Fisher WA, Fisher JD, Rye BJ: Understanding and promoting AIDS-preventive behavior: Insights from the theory of reasoned action. Health Psychol. 1995, 14 (3): 255-264.CrossRefPubMed Fisher WA, Fisher JD, Rye BJ: Understanding and promoting AIDS-preventive behavior: Insights from the theory of reasoned action. Health Psychol. 1995, 14 (3): 255-264.CrossRefPubMed
Metadata
Title
A cross-sectional assessment of knowledge, attitude and practice among Hepatitis-B patients in Quetta, Pakistan
Authors
Noman ul Haq
Mohamed Azmi Hassali
Asrul Akmal Shafie
Fahad Saleem
Maryam Farooqui
Abdul Haseeb
Hisham Aljadhey
Publication date
01-12-2013
Publisher
BioMed Central
Published in
BMC Public Health / Issue 1/2013
Electronic ISSN: 1471-2458
DOI
https://doi.org/10.1186/1471-2458-13-448

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