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Open Access 01-12-2011 | Study protocol

Prevention of Overweight in Infancy (POI.nz) study: a randomised controlled trial of sleep, food and activity interventions for preventing overweight from birth

Authors: Barry J Taylor, Anne-Louise M Heath, Barbara C Galland, Andrew R Gray, Julie A Lawrence, Rachel M Sayers, Kelly Dale, Kirsten J Coppell, Rachael W Taylor

Published in: BMC Public Health | Issue 1/2011

Abstract

Background

Rapid weight gain during the first three years of life predicts child and adult obesity, and also later cardiovascular and other morbidities. Cross-sectional studies suggest that infant diet, activity and sleep are linked to excessive weight gain. As intervention for overweight children is difficult, the aim of the Prevention of Overweight in Infancy (POI.nz) study is to evaluate two primary prevention strategies during late pregnancy and early childhood that could be delivered separately or together as part of normal health care.

Methods/Design

This four-arm randomised controlled trial is being conducted with 800 families recruited at booking in the only maternity unit in the city of Dunedin, New Zealand. Mothers are randomised during pregnancy to either a usual care group (7 core contacts with a provider of government funded "Well Child" care over 2 years) or to one of three intervention groups given education and support in addition to "Well Child" care: the Food, Activity and Breastfeeding group which receives 8 extra parent contacts over the first 2 years of life; the Sleep group which receives at least 3 extra parent contacts over the first 6 months of life with a focus on prevention of sleep problems and then active intervention if there is a sleep problem from 6 months to 2 years; or the Combination group which receives all extra contacts. The main outcome measures are conditional weight velocity (0-6, 6-12, 12-24 months) and body mass index z-score at 24 months, with secondary outcomes including sleep and physical activity (parent report, accelerometry), duration of breastfeeding, timing of introduction of solids, diet quality, and measures of family function and wellbeing (parental depression, child mindedness, discipline practices, family quality of life and health care use). This study will contribute to a prospective meta-analysis of early life obesity prevention studies in Australasia.

Discussion

Infancy is likely to be the most effective time to establish patterns of behaviour around food, activity and sleep that promote healthy child and adult weight. The POI.nz study will determine the extent to which sleep, food and activity interventions in infancy prevent the development of overweight.

Trial Registration

Clinical Trials NCT00892983

Prospective meta-analysis registered on PROSPERO CRD420111188. Available from http://www.crd.york.ac.uk/PROSPERO

Available only for authorised users

International Comparisons of Obesity Prevalence. [http://www.noo.org.uk/NOO_about_obesity/international/]

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The pre-publication history for this paper can be accessed here:http://www.biomedcentral.com/1471-2458/11/942/prepub

Title: Prevention of Overweight in Infancy (POI.nz) study: a randomised controlled trial of sleep, food and activity interventions for preventing overweight from birth
Authors: Barry J Taylor
Anne-Louise M Heath
Barbara C Galland
Andrew R Gray
Julie A Lawrence
Rachel M Sayers
Kelly Dale
Kirsten J Coppell
Rachael W Taylor
Publication date: 01-12-2011
Publisher: BioMed Central
Published in: BMC Public Health / Issue 1/2011
Electronic ISSN: 1471-2458
DOI: https://doi.org/10.1186/1471-2458-11-942

Keynote webinar | Spotlight on sleep in brain health

Springer Medicine

Prevention of Overweight in Infancy (POI.nz) study: a randomised controlled trial of sleep, food and activity interventions for preventing overweight from birth

Abstract

Background

Methods/Design

Discussion

Trial Registration

Keynote webinar | Spotlight on sleep in brain health

Springer Medicine

Abstract

Background

Methods/Design

Discussion

Trial Registration

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A qualitative study of older adults' responses to sitting-time questions: do we get the information we want?

Relationships between stress, coping and depressive symptoms among overseas university preparatory Chinese students: a cross-sectional study

Trial Protocol: Communicating DNA-based risk assessments for Crohn's disease: a randomised controlled trial assessing impact upon stopping smoking

Using clinical trial data and linked administrative health data to reduce the risk of adverse events associated with the uptake of newly released drugs by older Australians: a model process