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Published in: BMC Public Health 1/2011

Open Access 01-12-2011 | Correspondence

Health impact of US military service in a large population-based military cohort: findings of the Millennium Cohort Study, 2001-2008

Authors: Tyler C Smith, Isabel G Jacobson, Tomoko I Hooper, Cynthia A LeardMann, Edward J Boyko, Besa Smith, Gary D Gackstetter, Timothy S Wells, Paul J Amoroso, Gregory C Gray, James R Riddle, Margaret AK Ryan, the Millennium Cohort Study Team

Published in: BMC Public Health | Issue 1/2011

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Abstract

Background

Combat-intense, lengthy, and multiple deployments in Iraq and Afghanistan have characterized the new millennium. The US military's all-volunteer force has never been better trained and technologically equipped to engage enemy combatants in multiple theaters of operations. Nonetheless, concerns over potential lasting effects of deployment on long-term health continue to mount and are yet to be elucidated. This report outlines how findings from the first 7 years of the Millennium Cohort Study have helped to address health concerns related to military service including deployments.

Methods

The Millennium Cohort Study was designed in the late 1990s to address veteran and public concerns for the first time using prospectively collected health and behavioral data.

Results

Over 150 000 active-duty, reserve, and National Guard personnel from all service branches have enrolled, and more than 70% of the first 2 enrollment panels submitted at least 1 follow-up survey. Approximately half of the Cohort has deployed in support of operations in Iraq and Afghanistan.

Conclusion

The Millennium Cohort Study is providing prospective data that will guide public health policymakers for years to come by exploring associations between military exposures and important health outcomes. Strategic studies aim to identify, reduce, and prevent adverse health outcomes that may be associated with military service, including those related to deployment.
Literature
1.
go back to reference Committee on Measuring the Health of Gulf War Veterans IoM: Gulf War Veterans: Measuring Health. 1999, Washington, DC: National Academy Press Committee on Measuring the Health of Gulf War Veterans IoM: Gulf War Veterans: Measuring Health. 1999, Washington, DC: National Academy Press
4.
go back to reference Ryan MA, Smith TC, Smith B, Amoroso P, Boyko EJ, Gray GC, Gackstetter GD, Riddle JR, Wells TS, Gumbs G, Corbeil TE, Hooper TI: Millennium Cohort: enrollment begins a 21-year contribution to understanding the impact of military service. J Clin Epidemiol. 2007, 60 (2): 181-191. 10.1016/j.jclinepi.2006.05.009.CrossRefPubMed Ryan MA, Smith TC, Smith B, Amoroso P, Boyko EJ, Gray GC, Gackstetter GD, Riddle JR, Wells TS, Gumbs G, Corbeil TE, Hooper TI: Millennium Cohort: enrollment begins a 21-year contribution to understanding the impact of military service. J Clin Epidemiol. 2007, 60 (2): 181-191. 10.1016/j.jclinepi.2006.05.009.CrossRefPubMed
5.
go back to reference Gray GC, Chesbrough KB, Ryan MAK, Amoroso PJ, Boyko EJ, Gackstetter GD, Riddle JR, Hooper TI: The Millennium Cohort Study: a 21-year prospective cohort study of 140,000 military personnel. Mil Med. 2002, 167 (6): 483-488.PubMed Gray GC, Chesbrough KB, Ryan MAK, Amoroso PJ, Boyko EJ, Gackstetter GD, Riddle JR, Hooper TI: The Millennium Cohort Study: a 21-year prospective cohort study of 140,000 military personnel. Mil Med. 2002, 167 (6): 483-488.PubMed
6.
go back to reference Wells TS, Jacobson IG, Smith TC, Spooner CN, Smith B, Reed RJ, Amoroso PJ, Ryan MA, for the Millennium Cohort Study Team: Prior health care utilization as a potential determinant of enrollment in a 21-year prospective study, the Millennium Cohort Study. Eur J Epidemiol. 2008, 23 (2): 79-87. 10.1007/s10654-007-9216-0.CrossRefPubMed Wells TS, Jacobson IG, Smith TC, Spooner CN, Smith B, Reed RJ, Amoroso PJ, Ryan MA, for the Millennium Cohort Study Team: Prior health care utilization as a potential determinant of enrollment in a 21-year prospective study, the Millennium Cohort Study. Eur J Epidemiol. 2008, 23 (2): 79-87. 10.1007/s10654-007-9216-0.CrossRefPubMed
7.
go back to reference Smith TC, Smith B, Jacobson IG, Corbeil TE, Ryan MA, for the Millennium Cohort Study Team: Reliability of standard health assessment instruments in a large, population-based cohort study. Ann Epidemiol. 2007, 17 (4): 271-284. 10.1016/j.annepidem.2006.10.003.CrossRef Smith TC, Smith B, Jacobson IG, Corbeil TE, Ryan MA, for the Millennium Cohort Study Team: Reliability of standard health assessment instruments in a large, population-based cohort study. Ann Epidemiol. 2007, 17 (4): 271-284. 10.1016/j.annepidem.2006.10.003.CrossRef
8.
go back to reference Smith TC, Jacobson IG, Smith B, Hooper TI, Ryan MA, for the Millennium Cohort Study Team: The occupational role of women in military service: validation of occupation and prevalence of exposures in the Millennium Cohort Study. Int J Environ Health Res. 2007, 17 (4): 271-284. 10.1080/09603120701372243.CrossRefPubMed Smith TC, Jacobson IG, Smith B, Hooper TI, Ryan MA, for the Millennium Cohort Study Team: The occupational role of women in military service: validation of occupation and prevalence of exposures in the Millennium Cohort Study. Int J Environ Health Res. 2007, 17 (4): 271-284. 10.1080/09603120701372243.CrossRefPubMed
9.
go back to reference Smith B, Wingard DL, Ryan MA, Macera CA, Patterson TL, Slymen DJ, for the Millennium Cohort Study Team: U.S. military deployment during 2001-2006: comparison of subjective and objective data sources in a large prospective health study. Ann Epidemiol. 2007, 17 (12): 976-982. 10.1016/j.annepidem.2007.07.102.CrossRefPubMed Smith B, Wingard DL, Ryan MA, Macera CA, Patterson TL, Slymen DJ, for the Millennium Cohort Study Team: U.S. military deployment during 2001-2006: comparison of subjective and objective data sources in a large prospective health study. Ann Epidemiol. 2007, 17 (12): 976-982. 10.1016/j.annepidem.2007.07.102.CrossRefPubMed
10.
go back to reference Smith B, Smith TC, Gray GC, Ryan MA, for the Millennium Cohort Study Team: When epidemiology meets the Internet: Web-based surveys in the Millennium Cohort Study. Am J Epidemiol. 2007, 166 (11): 1345-1354. 10.1093/aje/kwm212.CrossRefPubMed Smith B, Smith TC, Gray GC, Ryan MA, for the Millennium Cohort Study Team: When epidemiology meets the Internet: Web-based surveys in the Millennium Cohort Study. Am J Epidemiol. 2007, 166 (11): 1345-1354. 10.1093/aje/kwm212.CrossRefPubMed
11.
go back to reference Smith B, Leard CA, Smith TC, Reed RJ, Ryan MA, for the Millennium Cohort Study Team: Anthrax vaccination in the Millennium Cohort; validation and measures of health. Am J Prev Med. 2007, 32 (4): 347-353. 10.1016/j.amepre.2006.12.015.CrossRefPubMed Smith B, Leard CA, Smith TC, Reed RJ, Ryan MA, for the Millennium Cohort Study Team: Anthrax vaccination in the Millennium Cohort; validation and measures of health. Am J Prev Med. 2007, 32 (4): 347-353. 10.1016/j.amepre.2006.12.015.CrossRefPubMed
12.
go back to reference Riddle JR, Smith TC, Smith B, Corbeil TE, Engel CC, Wells TS, Hoge CW, Adkins J, Zamorski M, Blazer D: Millennium Cohort: the 2001-2003 baseline prevalence of mental disorders in the U.S. military. J Clin Epidemiol. 2007, 60 (2): 192-201. 10.1016/j.jclinepi.2006.04.008.CrossRefPubMed Riddle JR, Smith TC, Smith B, Corbeil TE, Engel CC, Wells TS, Hoge CW, Adkins J, Zamorski M, Blazer D: Millennium Cohort: the 2001-2003 baseline prevalence of mental disorders in the U.S. military. J Clin Epidemiol. 2007, 60 (2): 192-201. 10.1016/j.jclinepi.2006.04.008.CrossRefPubMed
13.
go back to reference LeardMann CA, Smith B, Smith TC, Wells TS, Ryan MA, for the Millennium Cohort Study Team: Smallpox vaccination: comparison of self-reported and electronic vaccine records in the Millennium Cohort Study. Hum Vaccin. 2007, 3 (6): 245-251.CrossRefPubMed LeardMann CA, Smith B, Smith TC, Wells TS, Ryan MA, for the Millennium Cohort Study Team: Smallpox vaccination: comparison of self-reported and electronic vaccine records in the Millennium Cohort Study. Hum Vaccin. 2007, 3 (6): 245-251.CrossRefPubMed
14.
go back to reference Chretien JP, Chu LK, Smith TC, Smith B, Ryan MA: Demographic and occupational predictors of early response to a mailed invitation to enroll in a longitudinal health study. BMC Med Res Methodol. 2007, 7: 6-10.1186/1471-2288-7-6.CrossRefPubMedPubMedCentral Chretien JP, Chu LK, Smith TC, Smith B, Ryan MA: Demographic and occupational predictors of early response to a mailed invitation to enroll in a longitudinal health study. BMC Med Res Methodol. 2007, 7: 6-10.1186/1471-2288-7-6.CrossRefPubMedPubMedCentral
15.
go back to reference Smith TC, Zamorski M, Smith B, Riddle JR, Leardmann CA, Wells TS, Engel CC, Hoge CW, Adkins J, Blazer D, for the Millenium Cohort Study Team: The physical and mental health of a large military cohort: baseline functional health status of the Millennium Cohort. BMC Public Health. 2007, 7 (147): 340-10.1186/1471-2458-7-340.CrossRefPubMedPubMedCentral Smith TC, Zamorski M, Smith B, Riddle JR, Leardmann CA, Wells TS, Engel CC, Hoge CW, Adkins J, Blazer D, for the Millenium Cohort Study Team: The physical and mental health of a large military cohort: baseline functional health status of the Millennium Cohort. BMC Public Health. 2007, 7 (147): 340-10.1186/1471-2458-7-340.CrossRefPubMedPubMedCentral
16.
go back to reference Schmidt WC: World-Wide Web survey research benefits, potential problems, and solutions. Behav Res Methods Instrum Comput. 1997, 29: 274-9. 10.3758/BF03204826.CrossRef Schmidt WC: World-Wide Web survey research benefits, potential problems, and solutions. Behav Res Methods Instrum Comput. 1997, 29: 274-9. 10.3758/BF03204826.CrossRef
17.
go back to reference Welch KE, Leardmann CA, Jacobson IG, Speigle SJ, Smith B, Smith TC, Ryan MA, for the Millennium Cohort Study Team: Postcards encourage participant updates. Epidemiology. 2009, 20 (2): 313-314. 10.1097/EDE.0b013e3181931558.CrossRefPubMed Welch KE, Leardmann CA, Jacobson IG, Speigle SJ, Smith B, Smith TC, Ryan MA, for the Millennium Cohort Study Team: Postcards encourage participant updates. Epidemiology. 2009, 20 (2): 313-314. 10.1097/EDE.0b013e3181931558.CrossRefPubMed
18.
go back to reference Landis JR, Koch GG: The measurement of observer agreement for categorical data. Biometrics. 1977, 33 (1): 159-174. 10.2307/2529310.CrossRefPubMed Landis JR, Koch GG: The measurement of observer agreement for categorical data. Biometrics. 1977, 33 (1): 159-174. 10.2307/2529310.CrossRefPubMed
19.
go back to reference Mazzuchi JF, Claypool RG, Hyams KC, Trump D, Riddle J, Patterson RE, Bailey S: Protecting the health of U.S. military forces: a national obligation. Aviat Space Environ Med. 2000, 71 (3): 260-265.PubMed Mazzuchi JF, Claypool RG, Hyams KC, Trump D, Riddle J, Patterson RE, Bailey S: Protecting the health of U.S. military forces: a national obligation. Aviat Space Environ Med. 2000, 71 (3): 260-265.PubMed
20.
go back to reference Grabenstein JD, Winkenwerder W: US military smallpox vaccination program experience. JAMA. 2003, 289 (24): 3278-3282. 10.1001/jama.289.24.3278.CrossRefPubMed Grabenstein JD, Winkenwerder W: US military smallpox vaccination program experience. JAMA. 2003, 289 (24): 3278-3282. 10.1001/jama.289.24.3278.CrossRefPubMed
21.
go back to reference Wells TS, LeardMann CA, Smith TC, Smith B, Jacobson IG, Reed RJ, Ryan MA, for the Millennium Cohort Study Team: Self-reported adverse health events following smallpox vaccination in a large prospective study of US military service members. Hum Vaccin. 2008, 4 (2): 127-133. 10.4161/hv.4.2.5217.CrossRefPubMed Wells TS, LeardMann CA, Smith TC, Smith B, Jacobson IG, Reed RJ, Ryan MA, for the Millennium Cohort Study Team: Self-reported adverse health events following smallpox vaccination in a large prospective study of US military service members. Hum Vaccin. 2008, 4 (2): 127-133. 10.4161/hv.4.2.5217.CrossRefPubMed
22.
go back to reference Kang HK, Mahan CM, Lee KY, Magee CA, Murphy FM: Illnesses among United States veterans of the Gulf War: a population-based survey of 30,000 veterans. J Occup Environ Med. 2000, 42 (5): 491-501. 10.1097/00043764-200005000-00006.CrossRefPubMed Kang HK, Mahan CM, Lee KY, Magee CA, Murphy FM: Illnesses among United States veterans of the Gulf War: a population-based survey of 30,000 veterans. J Occup Environ Med. 2000, 42 (5): 491-501. 10.1097/00043764-200005000-00006.CrossRefPubMed
23.
go back to reference Hoge CW, Castro CA, Messer SC, McGurk D, Cotting DI, Koffman RL: Combat duty in Iraq and Afghanistan, mental health problems, and barriers to care. N Engl J Med. 2004, 351 (1): 13-22. 10.1056/NEJMoa040603.CrossRefPubMed Hoge CW, Castro CA, Messer SC, McGurk D, Cotting DI, Koffman RL: Combat duty in Iraq and Afghanistan, mental health problems, and barriers to care. N Engl J Med. 2004, 351 (1): 13-22. 10.1056/NEJMoa040603.CrossRefPubMed
24.
go back to reference Wells TS, LeardMann CA, Fortuna SO, Smith B, Smith TC, Ryan MA, Boyko EJ, Blazer D, for the Millennium Cohort Study Team: Depression is prospectively associated with combat deployment in support of the wars in Iraq and Afghanistan. AJPH. 2009 Wells TS, LeardMann CA, Fortuna SO, Smith B, Smith TC, Ryan MA, Boyko EJ, Blazer D, for the Millennium Cohort Study Team: Depression is prospectively associated with combat deployment in support of the wars in Iraq and Afghanistan. AJPH. 2009
25.
go back to reference Jacobson IG, Smith TC, Smith B, Keel PK, Amoroso PJ, Wells TS, Bathalon GP, Boyko EJ, Ryan MA: Disordered eating and weight changes after deployment: longitudinal assessment of a large US military cohort. Am J Epidemiol. 2009, 169 (4): 415-427. 10.1093/aje/kwn366.CrossRefPubMed Jacobson IG, Smith TC, Smith B, Keel PK, Amoroso PJ, Wells TS, Bathalon GP, Boyko EJ, Ryan MA: Disordered eating and weight changes after deployment: longitudinal assessment of a large US military cohort. Am J Epidemiol. 2009, 169 (4): 415-427. 10.1093/aje/kwn366.CrossRefPubMed
26.
go back to reference Smith TC, Wingard DL, Ryan MA, Kritz-Silverstein D, Slymen DJ, Sallis JF, for the Millennium Cohort Study Team: Prior assault and posttraumatic stress disorder after combat deployment. Epidemiology. 2008, 19 (3): 505-512. 10.1097/EDE.0b013e31816a9dff.CrossRefPubMed Smith TC, Wingard DL, Ryan MA, Kritz-Silverstein D, Slymen DJ, Sallis JF, for the Millennium Cohort Study Team: Prior assault and posttraumatic stress disorder after combat deployment. Epidemiology. 2008, 19 (3): 505-512. 10.1097/EDE.0b013e31816a9dff.CrossRefPubMed
27.
go back to reference Smith TC, Ryan MA, Wingard DL, Slymen DJ, Sallis JF, Kritz-Silverstein D, for the Millennium Cohort Study Team: New onset and persistent symptoms of post-traumatic stress disorder self reported after deployment and combat exposures: prospective population based US military cohort study. BMJ. 2008, 336 (7640): 366-371. 10.1136/bmj.39430.638241.AE.CrossRefPubMedPubMedCentral Smith TC, Ryan MA, Wingard DL, Slymen DJ, Sallis JF, Kritz-Silverstein D, for the Millennium Cohort Study Team: New onset and persistent symptoms of post-traumatic stress disorder self reported after deployment and combat exposures: prospective population based US military cohort study. BMJ. 2008, 336 (7640): 366-371. 10.1136/bmj.39430.638241.AE.CrossRefPubMedPubMedCentral
28.
go back to reference Salazar AM, Zitnay GA, Warden DL, Schwab KA: Defense and Veterans Head Injury Program: background and overview. J Head Trauma Rehabil. 2000, 15 (5): 1081-1091. 10.1097/00001199-200010000-00002.CrossRefPubMed Salazar AM, Zitnay GA, Warden DL, Schwab KA: Defense and Veterans Head Injury Program: background and overview. J Head Trauma Rehabil. 2000, 15 (5): 1081-1091. 10.1097/00001199-200010000-00002.CrossRefPubMed
29.
go back to reference Gray GC, Reed RJ, Kaiser KS, Smith TC, Gastanaga VM: The Seabee Health Study: self-reported multi-symptom conditions are common and strongly associated among Gulf War veterans. Am J Epidemiol. 2002, 155: 1033-1044. 10.1093/aje/155.11.1033.CrossRefPubMed Gray GC, Reed RJ, Kaiser KS, Smith TC, Gastanaga VM: The Seabee Health Study: self-reported multi-symptom conditions are common and strongly associated among Gulf War veterans. Am J Epidemiol. 2002, 155: 1033-1044. 10.1093/aje/155.11.1033.CrossRefPubMed
30.
go back to reference Knoke JD, Smith TC, Gray GC, Kaiser KS: Factor analysis of self-reported symptoms: Does it identify a Gulf War syndrome?. Am J Epidemiol. 2000, 152 (4): 379-388. 10.1093/aje/152.4.379.CrossRefPubMed Knoke JD, Smith TC, Gray GC, Kaiser KS: Factor analysis of self-reported symptoms: Does it identify a Gulf War syndrome?. Am J Epidemiol. 2000, 152 (4): 379-388. 10.1093/aje/152.4.379.CrossRefPubMed
31.
go back to reference Smith TC, Gray GC, Weir JC, Heller JM, Ryan MAK: Gulf War veterans and Iraqi nerve agents at Khamisiyah. Postwar hospitalization data revisited. Am J Epidemiol. 2003, 158: 456-467. Smith TC, Gray GC, Weir JC, Heller JM, Ryan MAK: Gulf War veterans and Iraqi nerve agents at Khamisiyah. Postwar hospitalization data revisited. Am J Epidemiol. 2003, 158: 456-467.
32.
go back to reference Gray GC, Smith TC, Knoke JD, Heller JM: The postwar hospitalization experience of Gulf War Veterans possibly exposed to chemical munitions destruction at Khamisiyah, Iraq. Am J Epidemiol. 1999, 150 (5): 532-540.CrossRefPubMed Gray GC, Smith TC, Knoke JD, Heller JM: The postwar hospitalization experience of Gulf War Veterans possibly exposed to chemical munitions destruction at Khamisiyah, Iraq. Am J Epidemiol. 1999, 150 (5): 532-540.CrossRefPubMed
33.
go back to reference Smith TC, Heller JM, Hooper TI, Gackstetter GD, Gray GC: Are veterans of the Gulf War experiencing illness from exposure to Kuwaiti oil well fire smoke? Department of Defense hospitalization data examined. Am J Epidemiol. 2002, 155 (10): 908-917. 10.1093/aje/155.10.908.CrossRefPubMed Smith TC, Heller JM, Hooper TI, Gackstetter GD, Gray GC: Are veterans of the Gulf War experiencing illness from exposure to Kuwaiti oil well fire smoke? Department of Defense hospitalization data examined. Am J Epidemiol. 2002, 155 (10): 908-917. 10.1093/aje/155.10.908.CrossRefPubMed
34.
go back to reference Milliken CS, Auchterlonie JL, Hoge CW: Longitudinal assessment of mental health problems among active and reserve component soldiers returning from the Iraq War. JAMA. 2007, 298 (18): 2141-2148. 10.1001/jama.298.18.2141.CrossRefPubMed Milliken CS, Auchterlonie JL, Hoge CW: Longitudinal assessment of mental health problems among active and reserve component soldiers returning from the Iraq War. JAMA. 2007, 298 (18): 2141-2148. 10.1001/jama.298.18.2141.CrossRefPubMed
35.
go back to reference Hoge CW, Auchterlonie JL, Milliken CS: Mental health problems, use of mental health services, and attrition from military service after returning from deployment to Iraq or Afghanistan. JAMA. 2006, 295 (9): 1023-1032. 10.1001/jama.295.9.1023.CrossRefPubMed Hoge CW, Auchterlonie JL, Milliken CS: Mental health problems, use of mental health services, and attrition from military service after returning from deployment to Iraq or Afghanistan. JAMA. 2006, 295 (9): 1023-1032. 10.1001/jama.295.9.1023.CrossRefPubMed
36.
go back to reference The Iowa Persian Gulf Study Group: Self-reported illness and health status among Persian Gulf War veterans: a population-based study. JAMA. 1997, 277 (3): 238-245. 10.1001/jama.277.3.238.CrossRef The Iowa Persian Gulf Study Group: Self-reported illness and health status among Persian Gulf War veterans: a population-based study. JAMA. 1997, 277 (3): 238-245. 10.1001/jama.277.3.238.CrossRef
37.
go back to reference Engel CC, Ursano R, Magruder C, Tartaglione R, Jing Z, Labbate LA, Debakey S: Psychological conditions diagnosed among veterans seeking Department of Defense Care for Gulf War-related health concerns. J Occup Environ Med. 1999, 41 (5): 384-392. 10.1097/00043764-199905000-00006.CrossRefPubMed Engel CC, Ursano R, Magruder C, Tartaglione R, Jing Z, Labbate LA, Debakey S: Psychological conditions diagnosed among veterans seeking Department of Defense Care for Gulf War-related health concerns. J Occup Environ Med. 1999, 41 (5): 384-392. 10.1097/00043764-199905000-00006.CrossRefPubMed
38.
go back to reference Toomey R, Kang HK, Karlinsky J, Baker DG, Vasterling JJ, Alpern R, Reda DJ, Henderson WG, Murphy FM, Eisen SA: Mental health of US Gulf War veterans 10 years after the war. Br J Psychiatry. 2007, 190: 385-393. 10.1192/bjp.bp.105.019539.CrossRefPubMed Toomey R, Kang HK, Karlinsky J, Baker DG, Vasterling JJ, Alpern R, Reda DJ, Henderson WG, Murphy FM, Eisen SA: Mental health of US Gulf War veterans 10 years after the war. Br J Psychiatry. 2007, 190: 385-393. 10.1192/bjp.bp.105.019539.CrossRefPubMed
39.
go back to reference Iversen A, Waterdrinker A, Fear N, Greenberg N, Barker C, Hotopf M, Hull L, Wessely S: Factors associated with heavy alcohol consumption in the U.K. armed forces: data from a health survey of Gulf, Bosnia, and era veterans. Mil Med. 2007, 172 (9): 956-961.CrossRefPubMed Iversen A, Waterdrinker A, Fear N, Greenberg N, Barker C, Hotopf M, Hull L, Wessely S: Factors associated with heavy alcohol consumption in the U.K. armed forces: data from a health survey of Gulf, Bosnia, and era veterans. Mil Med. 2007, 172 (9): 956-961.CrossRefPubMed
40.
go back to reference Hotopf M, Hull L, Fear NT, Browne T, Horn O, Iversen A, Jones M, Murphy D, Bland D, Earnshaw M, Greenberg N, Hughes JH, Tate AR, Dandeker C, Rona R, Wessely S: The health of UK military personnel who deployed to the 2003 Iraq war: a cohort study. Lancet. 2006, 367 (9524): 1731-1741. 10.1016/S0140-6736(06)68662-5.CrossRefPubMed Hotopf M, Hull L, Fear NT, Browne T, Horn O, Iversen A, Jones M, Murphy D, Bland D, Earnshaw M, Greenberg N, Hughes JH, Tate AR, Dandeker C, Rona R, Wessely S: The health of UK military personnel who deployed to the 2003 Iraq war: a cohort study. Lancet. 2006, 367 (9524): 1731-1741. 10.1016/S0140-6736(06)68662-5.CrossRefPubMed
41.
go back to reference Smith TC, Wingard DL, Ryan MAK, Kritz-Silverstein D, Slymen DJ, Sallis JF, for the Millennium Cohort Study Team: PTSD prevalence, associated exposures, and functional health outcomes in a large, population-based military cohort. Public Health Rep. 2009, 124: 90-102.PubMedPubMedCentral Smith TC, Wingard DL, Ryan MAK, Kritz-Silverstein D, Slymen DJ, Sallis JF, for the Millennium Cohort Study Team: PTSD prevalence, associated exposures, and functional health outcomes in a large, population-based military cohort. Public Health Rep. 2009, 124: 90-102.PubMedPubMedCentral
42.
go back to reference LeardMann CA, Smith TC, Smith B, Wells TS, Ryan MA: Baseline self reported functional health and vulnerability to post-traumatic stress disorder after combat deployment: prospective US military cohort study. BMJ. 2009, 338: b1273-10.1136/bmj.b1273.CrossRefPubMedPubMedCentral LeardMann CA, Smith TC, Smith B, Wells TS, Ryan MA: Baseline self reported functional health and vulnerability to post-traumatic stress disorder after combat deployment: prospective US military cohort study. BMJ. 2009, 338: b1273-10.1136/bmj.b1273.CrossRefPubMedPubMedCentral
43.
go back to reference Jacobson IG, Ryan MA, Hooper TI, Smith TC, Amoroso PJ, Boyko EJ, Gackstetter GD, Wells TS, Bell NS: Alcohol use and alcohol-related problems before and after military combat deployment. JAMA. 2008, 300 (6): 663-675. 10.1001/jama.300.6.663.CrossRefPubMedPubMedCentral Jacobson IG, Ryan MA, Hooper TI, Smith TC, Amoroso PJ, Boyko EJ, Gackstetter GD, Wells TS, Bell NS: Alcohol use and alcohol-related problems before and after military combat deployment. JAMA. 2008, 300 (6): 663-675. 10.1001/jama.300.6.663.CrossRefPubMedPubMedCentral
44.
go back to reference Smith B, Wong CA, Smith TC, Boyko EJ, Gackstetter GD: Newly reported respiratory symptoms and conditions among military personnel deployed to Iraq and Afghanistan: a prospective population-based study. Am J Epidemiol. 2009, 170 (11): 1433-1442. 10.1093/aje/kwp287.CrossRefPubMed Smith B, Wong CA, Smith TC, Boyko EJ, Gackstetter GD: Newly reported respiratory symptoms and conditions among military personnel deployed to Iraq and Afghanistan: a prospective population-based study. Am J Epidemiol. 2009, 170 (11): 1433-1442. 10.1093/aje/kwp287.CrossRefPubMed
45.
go back to reference Granado NS, Smith TC, Swanson GM, Harris RB, Shahar E, Smith B, Boyko EJ, Wells TS, Ryan MA, for the Millennium Cohort Study Team: Newly reported hypertension after military combat deployment in a large population-based study. Hypertension. 2009, 54 (5): 966-973. 10.1161/HYPERTENSIONAHA.109.132555.CrossRefPubMed Granado NS, Smith TC, Swanson GM, Harris RB, Shahar E, Smith B, Boyko EJ, Wells TS, Ryan MA, for the Millennium Cohort Study Team: Newly reported hypertension after military combat deployment in a large population-based study. Hypertension. 2009, 54 (5): 966-973. 10.1161/HYPERTENSIONAHA.109.132555.CrossRefPubMed
46.
go back to reference Institute of Medicine: Returning Home from Iraq and Afghanistan: Preliminary Assessment of Readjustment Needs of Veterans, Service Members, and Their Families. 2010, Washington, DC: The National Academies Press Institute of Medicine: Returning Home from Iraq and Afghanistan: Preliminary Assessment of Readjustment Needs of Veterans, Service Members, and Their Families. 2010, Washington, DC: The National Academies Press
47.
go back to reference Jain NB, Hart JE, Smith TJ, Garshick E, Laden F: Smoking behavior in trucking industry workers. Am J Ind Med. 2006, 49 (12): 1013-1020. 10.1002/ajim.20399.CrossRefPubMedPubMedCentral Jain NB, Hart JE, Smith TJ, Garshick E, Laden F: Smoking behavior in trucking industry workers. Am J Ind Med. 2006, 49 (12): 1013-1020. 10.1002/ajim.20399.CrossRefPubMedPubMedCentral
48.
go back to reference Acierno RA, Kilpatrick DG, Resnick HS, Saunders BE, Best CL: Violent assault, posttraumatic stress disorder, and depression. Risk factors for cigarette use among adult women. Behav Modif. 1996, 20 (4): 363-384. 10.1177/01454455960204001.CrossRefPubMed Acierno RA, Kilpatrick DG, Resnick HS, Saunders BE, Best CL: Violent assault, posttraumatic stress disorder, and depression. Risk factors for cigarette use among adult women. Behav Modif. 1996, 20 (4): 363-384. 10.1177/01454455960204001.CrossRefPubMed
49.
go back to reference Castro FG, Maddahian E, Newcomb MD, Bentler PM: A multivariate model of the determinants of cigarette smoking among adolescents. J Health Soc Behav. 1987, 28 (3): 273-289. 10.2307/2136846.CrossRefPubMed Castro FG, Maddahian E, Newcomb MD, Bentler PM: A multivariate model of the determinants of cigarette smoking among adolescents. J Health Soc Behav. 1987, 28 (3): 273-289. 10.2307/2136846.CrossRefPubMed
50.
go back to reference Smith B, Ryan MA, Wingard DL, Patterson TL, Slymen DJ, Macera CA: Cigarette smoking and military deployment: a prospective evaluation. Am J Prev Med. 2008, 35 (6): 539-546. 10.1016/j.amepre.2008.07.009.CrossRefPubMed Smith B, Ryan MA, Wingard DL, Patterson TL, Slymen DJ, Macera CA: Cigarette smoking and military deployment: a prospective evaluation. Am J Prev Med. 2008, 35 (6): 539-546. 10.1016/j.amepre.2008.07.009.CrossRefPubMed
51.
go back to reference Lande RG, Marin BA, Chang AS, Lande GR: Survey of alcohol use in the U.S. Army. J Addict Dis. 2008, 27 (3): 115-121. 10.1080/10550880802122711.CrossRefPubMed Lande RG, Marin BA, Chang AS, Lande GR: Survey of alcohol use in the U.S. Army. J Addict Dis. 2008, 27 (3): 115-121. 10.1080/10550880802122711.CrossRefPubMed
52.
go back to reference Spitzer RL, Williams JB, Kroenke K, Linzer M, deGruy FV, Hahn SR, Brody D, Johnson JG: Utility of a new procedure for diagnosing mental disorders in primary care. The PRIME-MD 1000 Study. JAMA. 1994, 272 (22): 1749-1756. 10.1001/jama.272.22.1749.CrossRefPubMed Spitzer RL, Williams JB, Kroenke K, Linzer M, deGruy FV, Hahn SR, Brody D, Johnson JG: Utility of a new procedure for diagnosing mental disorders in primary care. The PRIME-MD 1000 Study. JAMA. 1994, 272 (22): 1749-1756. 10.1001/jama.272.22.1749.CrossRefPubMed
53.
go back to reference Dohrenwend BP, Turner JB, Turse NA, Adams BG, Koenen KC, Marshall R: The psychological risks of Vietnam for U.S. veterans: a revisit with new data and methods. Science. 2006, 313 (5789): 979-982. 10.1126/science.1128944.CrossRefPubMedPubMedCentral Dohrenwend BP, Turner JB, Turse NA, Adams BG, Koenen KC, Marshall R: The psychological risks of Vietnam for U.S. veterans: a revisit with new data and methods. Science. 2006, 313 (5789): 979-982. 10.1126/science.1128944.CrossRefPubMedPubMedCentral
54.
go back to reference Thompson WW, Gottesman II, Zalewski C: Reconciling disparate prevalence rates of PTSD in large samples of US male Vietnam veterans and their controls. BMC Psychiatry. 2006, 6: 19-10.1186/1471-244X-6-19.CrossRefPubMedPubMedCentral Thompson WW, Gottesman II, Zalewski C: Reconciling disparate prevalence rates of PTSD in large samples of US male Vietnam veterans and their controls. BMC Psychiatry. 2006, 6: 19-10.1186/1471-244X-6-19.CrossRefPubMedPubMedCentral
55.
go back to reference Kang HK, Hyams KC: Mental health care needs among recent war veterans. N Engl J Med. 2005, 352 (13): 1289-10.1056/NEJMp058024.CrossRefPubMed Kang HK, Hyams KC: Mental health care needs among recent war veterans. N Engl J Med. 2005, 352 (13): 1289-10.1056/NEJMp058024.CrossRefPubMed
56.
go back to reference Kang HK, Natelson BH, Mahan CM, Lee KY, Murphy FM: Post-traumatic stress disorder and chronic fatigue syndrome-like illness among Gulf War veterans: a population-based survey of 30,000 veterans. Am J Epidemiol. 2003, 157 (2): 141-148. 10.1093/aje/kwf187.CrossRefPubMed Kang HK, Natelson BH, Mahan CM, Lee KY, Murphy FM: Post-traumatic stress disorder and chronic fatigue syndrome-like illness among Gulf War veterans: a population-based survey of 30,000 veterans. Am J Epidemiol. 2003, 157 (2): 141-148. 10.1093/aje/kwf187.CrossRefPubMed
57.
go back to reference Wolfe J, Erickson DJ, Sharkansky EJ, King DW, King LA: Course and predictors of posttraumatic stress disorder among Gulf War veterans: a prospective analysis. J Consult Clin Psychol. 1999, 67 (4): 520-528. 10.1037/0022-006X.67.4.520.CrossRefPubMed Wolfe J, Erickson DJ, Sharkansky EJ, King DW, King LA: Course and predictors of posttraumatic stress disorder among Gulf War veterans: a prospective analysis. J Consult Clin Psychol. 1999, 67 (4): 520-528. 10.1037/0022-006X.67.4.520.CrossRefPubMed
58.
go back to reference Stretch RH, Marlowe DH, Wright KM, Bliese PD, Knudson KH, Hoover CH: Post-traumatic stress disorder symptoms among Gulf War veterans. Mil Med. 1996, 161: 407-410.PubMed Stretch RH, Marlowe DH, Wright KM, Bliese PD, Knudson KH, Hoover CH: Post-traumatic stress disorder symptoms among Gulf War veterans. Mil Med. 1996, 161: 407-410.PubMed
59.
go back to reference Tanielian , Terri , Jaycox Lisa, eds: Invisible Wounds of War: Psychological and Cognitive Injuries, Their Consequences, and Services to Assist Recovery. 2008, Santa Monica: RAND Corporation Tanielian , Terri , Jaycox Lisa, eds: Invisible Wounds of War: Psychological and Cognitive Injuries, Their Consequences, and Services to Assist Recovery. 2008, Santa Monica: RAND Corporation
60.
go back to reference Seal KH, Metzler TJ, Gima KS, Bertenthal D, Maguen S, Marmar CR: Trends and risk factors for mental health diagnoses among Iraq and Afghanistan veterans using Department of Veterans Affairs health care, 2002-2008. Am J Public Health. 2009, 99 (9): 1651-1658. 10.2105/AJPH.2008.150284.CrossRefPubMedPubMedCentral Seal KH, Metzler TJ, Gima KS, Bertenthal D, Maguen S, Marmar CR: Trends and risk factors for mental health diagnoses among Iraq and Afghanistan veterans using Department of Veterans Affairs health care, 2002-2008. Am J Public Health. 2009, 99 (9): 1651-1658. 10.2105/AJPH.2008.150284.CrossRefPubMedPubMedCentral
61.
go back to reference Gondusky JS, Reiter MP: Protecting military convoys in Iraq: an examination of battle injuries sustained by a mechanized battalion during Operation Iraqi Freedom II. Mil Med. 2005, 170 (6): 546-549.CrossRefPubMed Gondusky JS, Reiter MP: Protecting military convoys in Iraq: an examination of battle injuries sustained by a mechanized battalion during Operation Iraqi Freedom II. Mil Med. 2005, 170 (6): 546-549.CrossRefPubMed
62.
go back to reference Murray CK, Reynolds JC, Schroeder JM, Harrison MB, Evans OM, Hospenthal DR: Spectrum of care provided at an echelon II Medical Unit during Operation Iraqi Freedom. Mil Med. 2005, 170 (6): 516-520.CrossRefPubMed Murray CK, Reynolds JC, Schroeder JM, Harrison MB, Evans OM, Hospenthal DR: Spectrum of care provided at an echelon II Medical Unit during Operation Iraqi Freedom. Mil Med. 2005, 170 (6): 516-520.CrossRefPubMed
63.
go back to reference Bell NS, Schwartz CE, Harford TC, Hollander IE, Amoroso PJ: Temporal changes in the nature of disability: U.S. Army soldiers discharged with disability, 1981-2005. Disabil Health J. 2008, 1 (3): 163-171. 10.1016/j.dhjo.2008.05.002.CrossRefPubMed Bell NS, Schwartz CE, Harford TC, Hollander IE, Amoroso PJ: Temporal changes in the nature of disability: U.S. Army soldiers discharged with disability, 1981-2005. Disabil Health J. 2008, 1 (3): 163-171. 10.1016/j.dhjo.2008.05.002.CrossRefPubMed
64.
go back to reference Litow CD, Krahl PL: Public health potential of a disability tracking system: analysis of U.S. Navy and Marine Corps physical evaluation boards 2005-2006. Mil Med. 2007, 172 (12): 1270-1274.CrossRefPubMed Litow CD, Krahl PL: Public health potential of a disability tracking system: analysis of U.S. Navy and Marine Corps physical evaluation boards 2005-2006. Mil Med. 2007, 172 (12): 1270-1274.CrossRefPubMed
65.
go back to reference Centers for Disease Control Vietnam Experience Study: Postservice mortality among Vietnam veterans. JAMA. 1987, 257: 790-795. 10.1001/jama.257.6.790.CrossRef Centers for Disease Control Vietnam Experience Study: Postservice mortality among Vietnam veterans. JAMA. 1987, 257: 790-795. 10.1001/jama.257.6.790.CrossRef
66.
go back to reference Kang HK, Bullman TA, Macfarlane GJ, Gray GC: Mortality among US and UK veterans of the Persian Gulf War: a review. J Occup Environ Med. 2002, 59 (12): 794-799. 10.1136/oem.59.12.794.CrossRef Kang HK, Bullman TA, Macfarlane GJ, Gray GC: Mortality among US and UK veterans of the Persian Gulf War: a review. J Occup Environ Med. 2002, 59 (12): 794-799. 10.1136/oem.59.12.794.CrossRef
67.
go back to reference Kang HK, Bullman T: Mortality among US veterans of the Persian Gulf War. N Engl J Med. 1996, 335 (20): 1498-1504. 10.1056/NEJM199611143352006.CrossRefPubMed Kang HK, Bullman T: Mortality among US veterans of the Persian Gulf War. N Engl J Med. 1996, 335 (20): 1498-1504. 10.1056/NEJM199611143352006.CrossRefPubMed
68.
go back to reference Bell NS, Amoroso PJ, Wegman DH, Senier L: Proposed explanations for excess injury among veterans of the Persian Gulf War and a call for greater attention from policymakers and researchers. Inj Prev. 2001, 7 (1): 4-9. 10.1136/ip.7.1.4.CrossRefPubMedPubMedCentral Bell NS, Amoroso PJ, Wegman DH, Senier L: Proposed explanations for excess injury among veterans of the Persian Gulf War and a call for greater attention from policymakers and researchers. Inj Prev. 2001, 7 (1): 4-9. 10.1136/ip.7.1.4.CrossRefPubMedPubMedCentral
70.
go back to reference Boyko EJ, Jacobson IG, Smith B, Ryan MA, Hooper TI, Amoroso PJ, Gackstetter GD, E BC, Smith TC, for the Millennium Cohort Study Team: Risk of diabetes in US military service members in relation to combat deployment and mental health. Diabetes Care. 2010, 33 (8): 1771-1777. 10.2337/dc10-0296.CrossRefPubMedPubMedCentral Boyko EJ, Jacobson IG, Smith B, Ryan MA, Hooper TI, Amoroso PJ, Gackstetter GD, E BC, Smith TC, for the Millennium Cohort Study Team: Risk of diabetes in US military service members in relation to combat deployment and mental health. Diabetes Care. 2010, 33 (8): 1771-1777. 10.2337/dc10-0296.CrossRefPubMedPubMedCentral
71.
go back to reference Doyle P, Maconochie N, Ryan M: Reproductive health of Gulf War veterans. Philos Trans R Soc Lond B Biol Sci. 2006, 361 (1468): 571-584. 10.1098/rstb.2006.1817.CrossRefPubMedPubMedCentral Doyle P, Maconochie N, Ryan M: Reproductive health of Gulf War veterans. Philos Trans R Soc Lond B Biol Sci. 2006, 361 (1468): 571-584. 10.1098/rstb.2006.1817.CrossRefPubMedPubMedCentral
72.
go back to reference Dawber TR, Meadors GF, Moore FE: Epidemiological approaches to heart disease: the Framingham Study. Am J Public Health. 1951, 41: 279-286. 10.2105/AJPH.41.3.279.CrossRef Dawber TR, Meadors GF, Moore FE: Epidemiological approaches to heart disease: the Framingham Study. Am J Public Health. 1951, 41: 279-286. 10.2105/AJPH.41.3.279.CrossRef
73.
go back to reference Branum AM, Collman GW, Correa A, Keim SA, Kessel W, Kimmel CA, Klebanoff MA, Longnecker MP, Mendola P, Rigas M, Selevan SG, Scheidt PC, Schoendorf K, Smith-Khuri E, Yeargin-Allsopp M: The National Children's Study of environmental effects on child health and development. Environ Health Perspect. 2003, 111 (4): 642-646.PubMedPubMedCentral Branum AM, Collman GW, Correa A, Keim SA, Kessel W, Kimmel CA, Klebanoff MA, Longnecker MP, Mendola P, Rigas M, Selevan SG, Scheidt PC, Schoendorf K, Smith-Khuri E, Yeargin-Allsopp M: The National Children's Study of environmental effects on child health and development. Environ Health Perspect. 2003, 111 (4): 642-646.PubMedPubMedCentral
74.
go back to reference Smith B, Chu LK, Smith TC, Amoroso PJ, Boyko EJ, Hooper TI, Gackstetter GD, Ryan MA, for the Millennium Cohort Study Team: Challenges of self-reported medical conditions and electronic medical records among members of a large military cohort. BMC Med Res Methodol. 2008, 8: 37-10.1186/1471-2288-8-37.CrossRefPubMedPubMedCentral Smith B, Chu LK, Smith TC, Amoroso PJ, Boyko EJ, Hooper TI, Gackstetter GD, Ryan MA, for the Millennium Cohort Study Team: Challenges of self-reported medical conditions and electronic medical records among members of a large military cohort. BMC Med Res Methodol. 2008, 8: 37-10.1186/1471-2288-8-37.CrossRefPubMedPubMedCentral
75.
go back to reference Institute of Medicine: Strategies to Protect the Health of Deployed US Forces. Washington, DC. Edited by: Press NA. 1999 Institute of Medicine: Strategies to Protect the Health of Deployed US Forces. Washington, DC. Edited by: Press NA. 1999
76.
go back to reference Checkoway H: Prioritizing future resources for epidemiologic research on old and newly emerging occupational hazards. Med Lav. 2006, 97 (2): 175-181.PubMed Checkoway H: Prioritizing future resources for epidemiologic research on old and newly emerging occupational hazards. Med Lav. 2006, 97 (2): 175-181.PubMed
77.
go back to reference Spitzer RL, Kroenke K, Williams JB: Validation and utility of a self-report version of the PRIME-MD: the PHQ Primary Care Study. Primary care evaluation of mental disorders. JAMA. 1999, 282 (18): 1737-1744. 10.1001/jama.282.18.1737.CrossRefPubMed Spitzer RL, Kroenke K, Williams JB: Validation and utility of a self-report version of the PRIME-MD: the PHQ Primary Care Study. Primary care evaluation of mental disorders. JAMA. 1999, 282 (18): 1737-1744. 10.1001/jama.282.18.1737.CrossRefPubMed
78.
go back to reference Blanchard EB, Jones-Alexander J, Buckley TC, Forneris CA: Psychometric properties of the PTSD Checklist (PCL). Behav Res Ther. 1996, 34 (8): 669-673. 10.1016/0005-7967(96)00033-2.CrossRefPubMed Blanchard EB, Jones-Alexander J, Buckley TC, Forneris CA: Psychometric properties of the PTSD Checklist (PCL). Behav Res Ther. 1996, 34 (8): 669-673. 10.1016/0005-7967(96)00033-2.CrossRefPubMed
Metadata
Title
Health impact of US military service in a large population-based military cohort: findings of the Millennium Cohort Study, 2001-2008
Authors
Tyler C Smith
Isabel G Jacobson
Tomoko I Hooper
Cynthia A LeardMann
Edward J Boyko
Besa Smith
Gary D Gackstetter
Timothy S Wells
Paul J Amoroso
Gregory C Gray
James R Riddle
Margaret AK Ryan
the Millennium Cohort Study Team
Publication date
01-12-2011
Publisher
BioMed Central
Published in
BMC Public Health / Issue 1/2011
Electronic ISSN: 1471-2458
DOI
https://doi.org/10.1186/1471-2458-11-69

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