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Published in: BMC Pregnancy and Childbirth 1/2013

Open Access 01-12-2013 | Research article

Estimating the prevalence of obstetric fistula: a systematic review and meta-analysis

Authors: A J Adler, C Ronsmans, C Calvert, V Filippi

Published in: BMC Pregnancy and Childbirth | Issue 1/2013

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Abstract

Background

Obstetric fistula is a severe condition which has devastating consequences for a woman’s life. The estimation of the burden of fistula at the population level has been impaired by the rarity of diagnosis and the lack of rigorous studies. This study was conducted to determine the prevalence and incidence of fistula in low and middle income countries.

Methods

Six databases were searched, involving two separate searches: one on fistula specifically and one on broader maternal and reproductive morbidities. Studies including estimates of incidence and prevalence of fistula at the population level were included. We conducted meta-analyses of prevalence of fistula among women of reproductive age and the incidence of fistula among recently pregnant women.

Results

Nineteen studies were included in this review. The pooled prevalence in population-based studies was 0.29 (95% CI 0.00, 1.07) fistula per 1000 women of reproductive age in all regions. Separated by region we found 1.57 (95% CI 1.16, 2.06) in sub Saharan Africa and South Asia, 1.60 (95% CI 1.16, 2.10) per 1000 women of reproductive age in sub Saharan Africa and 1.20 (95% CI 0.10, 3.54) per 1000 in South Asia. The pooled incidence was 0.09 (95% CI 0.01, 0.25) per 1000 recently pregnant women.

Conclusions

Our study is the most comprehensive study of the burden of fistula to date. Our findings suggest that the prevalence of fistula is lower than previously reported. The low burden of fistula should not detract from their public health importance, however, given the preventability of the condition, and the devastating consequences of fistula.
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Literature
1.
go back to reference WHO: Obstetric fistula: guiding principles for clinical management and programme development. 2006, Geneva: World Health Organization WHO: Obstetric fistula: guiding principles for clinical management and programme development. 2006, Geneva: World Health Organization
2.
go back to reference Wall LL, Arrowsmith SD, Briggs ND, Browning A, Lassey A: The obstetric vesicovaginal fistula in the developing world. Obste & gyne survey. 2005, 60 (7 Suppl 1): S3-S51.CrossRef Wall LL, Arrowsmith SD, Briggs ND, Browning A, Lassey A: The obstetric vesicovaginal fistula in the developing world. Obste & gyne survey. 2005, 60 (7 Suppl 1): S3-S51.CrossRef
3.
go back to reference Danso KA, Martey JO, Wall LL, Elkins TE: The epidemiology of genitourinary fistulae in Kumasi, Ghana, 1977-1992. Int Urogynecol J Pelvic Floor Dysfunct. 1996, 7 (3): 117-120. 10.1007/BF01894198.CrossRefPubMed Danso KA, Martey JO, Wall LL, Elkins TE: The epidemiology of genitourinary fistulae in Kumasi, Ghana, 1977-1992. Int Urogynecol J Pelvic Floor Dysfunct. 1996, 7 (3): 117-120. 10.1007/BF01894198.CrossRefPubMed
4.
go back to reference Langkilde NC, Pless TK, Lundbeck F, Nerstrom B: Surgical repair of vesicovaginal fistulae–a ten-year retrospective study. Scand J Urol Nephrol. 1999, 33 (2): 100-103. 10.1080/003655999750016069.CrossRefPubMed Langkilde NC, Pless TK, Lundbeck F, Nerstrom B: Surgical repair of vesicovaginal fistulae–a ten-year retrospective study. Scand J Urol Nephrol. 1999, 33 (2): 100-103. 10.1080/003655999750016069.CrossRefPubMed
5.
go back to reference Karateke A, Cam C, Ozdemir A, Guney B, Vatansever D, Celik C: Characteristics of obstetric fistulas and the need for a prognostic classification system. Archives of Med Sci. 2010, 6 (2): 253-256.CrossRef Karateke A, Cam C, Ozdemir A, Guney B, Vatansever D, Celik C: Characteristics of obstetric fistulas and the need for a prognostic classification system. Archives of Med Sci. 2010, 6 (2): 253-256.CrossRef
6.
go back to reference Muleta M, Hamlin EC, Fantahun M, Kennedy RC, Tafesse B: Health and social problems encountered by treated and untreated obstetric fistula patients in rural Ethiopia. J Obstet Gynaecol Can. 2008, 30 (1): 44-50.CrossRefPubMed Muleta M, Hamlin EC, Fantahun M, Kennedy RC, Tafesse B: Health and social problems encountered by treated and untreated obstetric fistula patients in rural Ethiopia. J Obstet Gynaecol Can. 2008, 30 (1): 44-50.CrossRefPubMed
7.
go back to reference Wall LL, Karshima JA, Kirschner C, Arrowsmith SD: The obstetric vesicovaginal fistula: characteristics of 899 patients from Jos, Nigeria. Am J Obstet Gynecol. 2004, 190 (4): 1011-1019. 10.1016/j.ajog.2004.02.007.CrossRefPubMed Wall LL, Karshima JA, Kirschner C, Arrowsmith SD: The obstetric vesicovaginal fistula: characteristics of 899 patients from Jos, Nigeria. Am J Obstet Gynecol. 2004, 190 (4): 1011-1019. 10.1016/j.ajog.2004.02.007.CrossRefPubMed
8.
go back to reference Browning A, Fentahun W, Goh JT: The impact of surgical treatment on the mental health of women with obstetric fistula. BJOG. 2007, 114 (11): 1439-1441. 10.1111/j.1471-0528.2007.01419.x.CrossRefPubMed Browning A, Fentahun W, Goh JT: The impact of surgical treatment on the mental health of women with obstetric fistula. BJOG. 2007, 114 (11): 1439-1441. 10.1111/j.1471-0528.2007.01419.x.CrossRefPubMed
9.
go back to reference Hilton P, Ward A: Epidemiological and surgical aspects of urogenital fistulae: a review of 25 years’ experience in southeast Nigeria. Int Urogynecol J Pelvic Floor Dysfunct. 1998, 9 (4): 189-194. 10.1007/BF01901602.CrossRefPubMed Hilton P, Ward A: Epidemiological and surgical aspects of urogenital fistulae: a review of 25 years’ experience in southeast Nigeria. Int Urogynecol J Pelvic Floor Dysfunct. 1998, 9 (4): 189-194. 10.1007/BF01901602.CrossRefPubMed
10.
go back to reference Holme A, Breen M, MacArthur C: Obstetric fistulae: a study of women managed at the Monze Mission Hospital, Zambia. BJOG. 2007, 114 (8): 1010-1017. 10.1111/j.1471-0528.2007.01353.x.CrossRefPubMed Holme A, Breen M, MacArthur C: Obstetric fistulae: a study of women managed at the Monze Mission Hospital, Zambia. BJOG. 2007, 114 (8): 1010-1017. 10.1111/j.1471-0528.2007.01353.x.CrossRefPubMed
11.
go back to reference Goh JT, Sloane KM, Krause HG, Browning A, Akhter S: Mental health screening in women with genital tract fistulae. BJOG. 2005, 112 (9): 1328-1330. 10.1111/j.1471-0528.2005.00712.x.CrossRefPubMed Goh JT, Sloane KM, Krause HG, Browning A, Akhter S: Mental health screening in women with genital tract fistulae. BJOG. 2005, 112 (9): 1328-1330. 10.1111/j.1471-0528.2005.00712.x.CrossRefPubMed
13.
go back to reference Stanton C, Holtz SA, Ahmed S: Challenges in measuring obstetric fistula. Int J Gynaecol Obstet. 2007, 99 (Suppl 1): S4-S9.CrossRefPubMed Stanton C, Holtz SA, Ahmed S: Challenges in measuring obstetric fistula. Int J Gynaecol Obstet. 2007, 99 (Suppl 1): S4-S9.CrossRefPubMed
14.
go back to reference Leung TY, Chung TKH: Severe chronic morbidity following childbirth. Best Prac Res Clin Obstet Gynaecol. 2009, 23 (3): 401-423. 10.1016/j.bpobgyn.2009.01.002.CrossRef Leung TY, Chung TKH: Severe chronic morbidity following childbirth. Best Prac Res Clin Obstet Gynaecol. 2009, 23 (3): 401-423. 10.1016/j.bpobgyn.2009.01.002.CrossRef
15.
go back to reference Ronsmans C, Achadi E, Cohen S, Zazri A: Women’s recall of obstetric complications in south Kalimantan Indonesia. Stud Fam Plann. 1997, 28 (3): 203-214. 10.2307/2137888.CrossRefPubMed Ronsmans C, Achadi E, Cohen S, Zazri A: Women’s recall of obstetric complications in south Kalimantan Indonesia. Stud Fam Plann. 1997, 28 (3): 203-214. 10.2307/2137888.CrossRefPubMed
16.
go back to reference Filippi V, Ronsmans C, Gandaho T, Graham W, Alihonou E, Santos P: Women’s reports of severe (near-miss) obstetric complications in Benin. Stud Fam Plann. 2000, 31 (4): 309-324. 10.1111/j.1728-4465.2000.00309.x.CrossRefPubMed Filippi V, Ronsmans C, Gandaho T, Graham W, Alihonou E, Santos P: Women’s reports of severe (near-miss) obstetric complications in Benin. Stud Fam Plann. 2000, 31 (4): 309-324. 10.1111/j.1728-4465.2000.00309.x.CrossRefPubMed
17.
go back to reference Borenstein M, Hedges LV, Higgins JPT, Rothstein HR: A basic introduction to fixed-effect and random-effects models for meta-analysis. Res Syn Methods. 2010, 1 (2): 97-111. 10.1002/jrsm.12.CrossRef Borenstein M, Hedges LV, Higgins JPT, Rothstein HR: A basic introduction to fixed-effect and random-effects models for meta-analysis. Res Syn Methods. 2010, 1 (2): 97-111. 10.1002/jrsm.12.CrossRef
18.
go back to reference Muleta M, Fantahun M, Tafesse B, Hamlin EC, Kennedy RC: Obstetric fistula in rural Ethiopia. East Afr Med J. 2007, 84 (11): 525-533.PubMed Muleta M, Fantahun M, Tafesse B, Hamlin EC, Kennedy RC: Obstetric fistula in rural Ethiopia. East Afr Med J. 2007, 84 (11): 525-533.PubMed
19.
go back to reference Bhatia JC, Cleland J, Bhagavan L, Rao NS: Levels and determinants of gynecological morbidity in a district of south India. Stud Fam Plann. 1997, 28 (2): 95-103. 10.2307/2138112.CrossRefPubMed Bhatia JC, Cleland J, Bhagavan L, Rao NS: Levels and determinants of gynecological morbidity in a district of south India. Stud Fam Plann. 1997, 28 (2): 95-103. 10.2307/2138112.CrossRefPubMed
20.
go back to reference Fronczak N, Antelman G, Moran AC, Caulfield LE, Baqui AH: Delivery-related complications and early postpartum morbidity in Dhaka, Bangladesh. Int J of Gynecology & Obstetrics. 2005, 91 (3): 271-278. 10.1016/j.ijgo.2005.09.006.CrossRef Fronczak N, Antelman G, Moran AC, Caulfield LE, Baqui AH: Delivery-related complications and early postpartum morbidity in Dhaka, Bangladesh. Int J of Gynecology & Obstetrics. 2005, 91 (3): 271-278. 10.1016/j.ijgo.2005.09.006.CrossRef
21.
go back to reference Kalilani-Phiri LV, Umar E, Lazaro D, Lunguzi J, Chilungo A: Prevalence of obstetric fistula in Malawi. Int J Gynaecol Obstet. 2010, 109 (3): 204-208. 10.1016/j.ijgo.2009.12.019.CrossRefPubMed Kalilani-Phiri LV, Umar E, Lazaro D, Lunguzi J, Chilungo A: Prevalence of obstetric fistula in Malawi. Int J Gynaecol Obstet. 2010, 109 (3): 204-208. 10.1016/j.ijgo.2009.12.019.CrossRefPubMed
22.
go back to reference Vangeenderhuysen C, Prual A, Ould el Joud D: Obstetric fistulae: incidence estimates for sub-Saharan Africa. Int J Gynaecol Obstet. 2001, 73 (1): 65-66. 10.1016/S0020-7292(00)00374-X.CrossRefPubMed Vangeenderhuysen C, Prual A, Ould el Joud D: Obstetric fistulae: incidence estimates for sub-Saharan Africa. Int J Gynaecol Obstet. 2001, 73 (1): 65-66. 10.1016/S0020-7292(00)00374-X.CrossRefPubMed
23.
go back to reference Ijaiya MA, Aboyeji PA: Obstetric urogenital fistula: the Ilorin experience Nigeria. West Afr J Med. 2004, 23 (1): 7-9.PubMed Ijaiya MA, Aboyeji PA: Obstetric urogenital fistula: the Ilorin experience Nigeria. West Afr J Med. 2004, 23 (1): 7-9.PubMed
24.
go back to reference Walraven G, Scherf C, West B, Ekpo G, Paine K, Coleman R, Bailey R, Morison L: The burden of reproductive-organ disease in rural women in The Gambia West Africa. Lancet. 2001, 357 (9263): 1161-1167. 10.1016/S0140-6736(00)04333-6.CrossRefPubMed Walraven G, Scherf C, West B, Ekpo G, Paine K, Coleman R, Bailey R, Morison L: The burden of reproductive-organ disease in rural women in The Gambia West Africa. Lancet. 2001, 357 (9263): 1161-1167. 10.1016/S0140-6736(00)04333-6.CrossRefPubMed
25.
go back to reference Bulut A, Filippi V, Marshall T, Nalbant H, Yolsal N, Graham W: Contraceptive choice and reproductive morbidity in Istanbul. Stud Fam Plann. 1997, 28 (1): 35-43. 10.2307/2137969.CrossRefPubMed Bulut A, Filippi V, Marshall T, Nalbant H, Yolsal N, Graham W: Contraceptive choice and reproductive morbidity in Istanbul. Stud Fam Plann. 1997, 28 (1): 35-43. 10.2307/2137969.CrossRefPubMed
26.
go back to reference Al-Qutob R, Mawajdeh S, Massad D: Can a home-based pelvic examination be used in assessing reproductive morbidity in population-based studies? A Jordanian experience. J Adv Nurs. 2001, 33 (5): 603-612. 10.1046/j.1365-2648.2001.01707.x.CrossRefPubMed Al-Qutob R, Mawajdeh S, Massad D: Can a home-based pelvic examination be used in assessing reproductive morbidity in population-based studies? A Jordanian experience. J Adv Nurs. 2001, 33 (5): 603-612. 10.1046/j.1365-2648.2001.01707.x.CrossRefPubMed
27.
go back to reference Deeb ME, Awwad J, Yeretzian JS, Kaspar HG: Prevalence of reproductive tract infections, genital prolapse, and obesity in a rural community in Lebanon. Bull World Health Organ. 2003, 81 (9): 639-645.PubMedPubMedCentral Deeb ME, Awwad J, Yeretzian JS, Kaspar HG: Prevalence of reproductive tract infections, genital prolapse, and obesity in a rural community in Lebanon. Bull World Health Organ. 2003, 81 (9): 639-645.PubMedPubMedCentral
28.
go back to reference Al-Riyami A, Afifi M, Morsi M, Mabry R: A national study of gynecological morbidities in Oman Effect of women’s autonomy. Saudi Med J. 2007, 28 (6): 881-890.PubMed Al-Riyami A, Afifi M, Morsi M, Mabry R: A national study of gynecological morbidities in Oman Effect of women’s autonomy. Saudi Med J. 2007, 28 (6): 881-890.PubMed
29.
go back to reference Younis N, Khattab H, Zurayk H, el-Mouelhy M, Amin MF, Farag AM: A community study of gynecological and related morbidities in rural Egypt. Stud Fam Plann. 1993, 24 (3): 175-186. 10.2307/2939232.CrossRefPubMed Younis N, Khattab H, Zurayk H, el-Mouelhy M, Amin MF, Farag AM: A community study of gynecological and related morbidities in rural Egypt. Stud Fam Plann. 1993, 24 (3): 175-186. 10.2307/2939232.CrossRefPubMed
30.
go back to reference Filippi V, Ganaba R, Baggaley RF, Marshall T, Storeng KT, Sombié I, Ouattara F, Ouedraogo T, Akoum M, Meda N: Health of women after severe obstetric complications in Burkina Faso: a longitudinal study. Lancet. 2007, 370 (9595): 1329-1337. 10.1016/S0140-6736(07)61574-8.CrossRefPubMed Filippi V, Ganaba R, Baggaley RF, Marshall T, Storeng KT, Sombié I, Ouattara F, Ouedraogo T, Akoum M, Meda N: Health of women after severe obstetric complications in Burkina Faso: a longitudinal study. Lancet. 2007, 370 (9595): 1329-1337. 10.1016/S0140-6736(07)61574-8.CrossRefPubMed
31.
go back to reference Filippi V, Goufodji S, Sismanidis C, Kanhonou L, Fottrell E, Ronsmans C, Alihonou E, Patel V: Effects of severe obstetric complications on women’s health and infant mortality in Benin. Trop Med Int Health. 2010, 15 (6): 733-742. 10.1111/j.1365-3156.2010.02534.x.CrossRefPubMedPubMedCentral Filippi V, Goufodji S, Sismanidis C, Kanhonou L, Fottrell E, Ronsmans C, Alihonou E, Patel V: Effects of severe obstetric complications on women’s health and infant mortality in Benin. Trop Med Int Health. 2010, 15 (6): 733-742. 10.1111/j.1365-3156.2010.02534.x.CrossRefPubMedPubMedCentral
32.
go back to reference Prual A, Huguet D, Garbin O, Rabe G: Severe obstetric morbidity of the third trimester, delivery and early puerperium in Niamey (Niger). Afr J Reprod Health. 1998, 2 (1): 10-19.PubMed Prual A, Huguet D, Garbin O, Rabe G: Severe obstetric morbidity of the third trimester, delivery and early puerperium in Niamey (Niger). Afr J Reprod Health. 1998, 2 (1): 10-19.PubMed
33.
go back to reference Ferdous J, Ahmed A, Dasgupta SK, Jahan M, Huda FA, Ronsmans C, Koblinsky M, Chowdhury ME: Occurrence and determinants of postpartum maternal morbidities and disabilities among women in Matlab, Bangladesh. J Health and Pop Nutrition. 2012, 30 (2): 143-158. Ferdous J, Ahmed A, Dasgupta SK, Jahan M, Huda FA, Ronsmans C, Koblinsky M, Chowdhury ME: Occurrence and determinants of postpartum maternal morbidities and disabilities among women in Matlab, Bangladesh. J Health and Pop Nutrition. 2012, 30 (2): 143-158.
34.
go back to reference Tehrani RF: Reproductive morbidity among Iranian women; issues often inappropriately addressed in health seeking behaviors. BMC Public Health. 2011, 11: 863-10.1186/1471-2458-11-863.CrossRefPubMedPubMedCentral Tehrani RF: Reproductive morbidity among Iranian women; issues often inappropriately addressed in health seeking behaviors. BMC Public Health. 2011, 11: 863-10.1186/1471-2458-11-863.CrossRefPubMedPubMedCentral
37.
go back to reference Health E, UNFPA: Obstetric fistula needs assessment report: Findings from nine African countries. 2003, New York: UNFPA Health E, UNFPA: Obstetric fistula needs assessment report: Findings from nine African countries. 2003, New York: UNFPA
38.
go back to reference Prual A, Bouvier-Colle MH, de Bernis L, Breart G: Severe maternal morbidity from direct obstetric causes in West Africa: incidence and case fatality rates. Bull World Health Organ. 2000, 78 (5): 593-602.PubMedPubMedCentral Prual A, Bouvier-Colle MH, de Bernis L, Breart G: Severe maternal morbidity from direct obstetric causes in West Africa: incidence and case fatality rates. Bull World Health Organ. 2000, 78 (5): 593-602.PubMedPubMedCentral
39.
40.
go back to reference Ronsmans C, Holtz S, Stanton C: Socioeconomic differentials in caesarean rates in developing countries: a retrospective analysis. Lancet. 2006, 368 (9546): 1516-1523. 10.1016/S0140-6736(06)69639-6.CrossRefPubMed Ronsmans C, Holtz S, Stanton C: Socioeconomic differentials in caesarean rates in developing countries: a retrospective analysis. Lancet. 2006, 368 (9546): 1516-1523. 10.1016/S0140-6736(06)69639-6.CrossRefPubMed
Metadata
Title
Estimating the prevalence of obstetric fistula: a systematic review and meta-analysis
Authors
A J Adler
C Ronsmans
C Calvert
V Filippi
Publication date
01-12-2013
Publisher
BioMed Central
Published in
BMC Pregnancy and Childbirth / Issue 1/2013
Electronic ISSN: 1471-2393
DOI
https://doi.org/10.1186/1471-2393-13-246

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