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Published in: BMC Infectious Diseases 1/2003

Open Access 01-12-2003 | Case report

Chlamydia trachomatisinfection in early neonatal period

Published in: BMC Infectious Diseases | Issue 1/2003

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Abstract

Background

The clinical characteristics of Chlamydia trachomatis respiratory tract infections in Japanese neonates were investigated.

Methods

Clinical, laboratory and microbiological characteristics of five infants with pneumonia due to C. trachomatis in early neonatal period were analyzed.

Results

Only C. trachomatis was identified in 4 infants. Both C. trachomatis and cytomegalovirus was identified in one. Wheezing, tachypnea and cyanosis were common in infants. Mothers of five infants had negative chlamydial EIAs at 20 weeks of gestation.

Conclusions

We identified five cases of C. trachomatis respiratory tract infections in early neonatal period with the possibility of intrauterine infection. Targeted screening, early diagnosis, and effective treatment of perinatal and neonatal chlamydial infections seems to be necessary
Literature
2.
go back to reference Niida Y, Numazaki K, Ikehata M, Umetsu M, Motoya H, Chiba S: Two full-term infants with Chlamydia trachomatis pneumonia in the early neonatal period. Eur J Pediatr. 1998, 157: 950-1. 10.1007/s004310050975.CrossRefPubMed Niida Y, Numazaki K, Ikehata M, Umetsu M, Motoya H, Chiba S: Two full-term infants with Chlamydia trachomatis pneumonia in the early neonatal period. Eur J Pediatr. 1998, 157: 950-1. 10.1007/s004310050975.CrossRefPubMed
3.
go back to reference Numazaki K, Niida Y: Two cases of Intrauterine Chlamydia trachomatis Infection. Antimicrobics and Infectious Diseases Newsletter. 2000, 18: 6-8. 10.1016/S1069-417X(00)88484-8.CrossRef Numazaki K, Niida Y: Two cases of Intrauterine Chlamydia trachomatis Infection. Antimicrobics and Infectious Diseases Newsletter. 2000, 18: 6-8. 10.1016/S1069-417X(00)88484-8.CrossRef
4.
go back to reference Gencay M, Koskiniemi ML, Fellman V, Amimala P, Vaheri A, Puolakkaonen M: Chlamydia trachomatis infection in mothers with preterm delivery and in their newborn infants. APMIS. 2001, 109: 636-40. 10.1034/j.1600-0463.2001.d01-186.x.CrossRefPubMed Gencay M, Koskiniemi ML, Fellman V, Amimala P, Vaheri A, Puolakkaonen M: Chlamydia trachomatis infection in mothers with preterm delivery and in their newborn infants. APMIS. 2001, 109: 636-40. 10.1034/j.1600-0463.2001.d01-186.x.CrossRefPubMed
5.
go back to reference Numazaki K, Ikehata M, Chiba S, Suzuki K, Hashimoto N: Unclassified serovars of Chlamydia trachomatis isolated from Japanese infants. Clin Microbiol Infect. 1998, 4: 519-23.CrossRef Numazaki K, Ikehata M, Chiba S, Suzuki K, Hashimoto N: Unclassified serovars of Chlamydia trachomatis isolated from Japanese infants. Clin Microbiol Infect. 1998, 4: 519-23.CrossRef
6.
go back to reference Ikehata M, Numazaki K, Chiba S: Analysis of Chlamydia trachomatis serovars in endocervical specimens derived from pregnant Japanese women. FEMS Immunol Med Microbiol. 2000, 27: 35-41. 10.1016/S0928-8244(99)00158-3.CrossRefPubMed Ikehata M, Numazaki K, Chiba S: Analysis of Chlamydia trachomatis serovars in endocervical specimens derived from pregnant Japanese women. FEMS Immunol Med Microbiol. 2000, 27: 35-41. 10.1016/S0928-8244(99)00158-3.CrossRefPubMed
7.
go back to reference Numazaki K, Chiba S, Niida Y, Komatsu M, Hashimoto N: Evaluation of diagnostic assays for neonatal and infantile chlamydial infections. Tohoku J Exp Med. 1993, 170: 123-9.CrossRefPubMed Numazaki K, Chiba S, Niida Y, Komatsu M, Hashimoto N: Evaluation of diagnostic assays for neonatal and infantile chlamydial infections. Tohoku J Exp Med. 1993, 170: 123-9.CrossRefPubMed
8.
go back to reference Numazaki K, Chiba S: Diagnostic value of rapid detection of Chlamydia trachomatis by using amplified enzyme immunoassay in infants with respiratory infections. Diagn Microbiol Infect Dis. 1993, 17: 233-4. 10.1016/0732-8893(93)90102-D.CrossRefPubMed Numazaki K, Chiba S: Diagnostic value of rapid detection of Chlamydia trachomatis by using amplified enzyme immunoassay in infants with respiratory infections. Diagn Microbiol Infect Dis. 1993, 17: 233-4. 10.1016/0732-8893(93)90102-D.CrossRefPubMed
9.
go back to reference Alger LS, Lovchik JC, Hebel JR, Blackmon LR, Crenshaw MC: The association of Chlamydia trachomatis Neisseria gonorrhoeae, and group B streptococci with preterm rupture of the membranes and pregnancy outcome. Am J Obstet Gynecol. 1988, 159: 397-404.CrossRefPubMed Alger LS, Lovchik JC, Hebel JR, Blackmon LR, Crenshaw MC: The association of Chlamydia trachomatis Neisseria gonorrhoeae, and group B streptococci with preterm rupture of the membranes and pregnancy outcome. Am J Obstet Gynecol. 1988, 159: 397-404.CrossRefPubMed
10.
go back to reference Ekwo EE, Gosselink CA, Woolson R, Moawad A: Risks for premature rupture of amniotic membranes. Int J Epidemiol. 1993, 22: 495-503.CrossRefPubMed Ekwo EE, Gosselink CA, Woolson R, Moawad A: Risks for premature rupture of amniotic membranes. Int J Epidemiol. 1993, 22: 495-503.CrossRefPubMed
11.
go back to reference McGregor JA, French JI, Parker R, et al: Prevention of premature birth by screening and treatment for common genital tract infections: results of a prospective controlled evaluation. Am J Obstet Gynecol. 1995, 173: 157-67.CrossRefPubMed McGregor JA, French JI, Parker R, et al: Prevention of premature birth by screening and treatment for common genital tract infections: results of a prospective controlled evaluation. Am J Obstet Gynecol. 1995, 173: 157-67.CrossRefPubMed
12.
13.
go back to reference Numazaki K, Ikehata M, Akashi E, Kusaka T, Chiba S: Seropositivity to Chlamydia trachomatis during pregnancy and perinatal complications. J Infect Chemother. 1998, 4: 28-31.CrossRef Numazaki K, Ikehata M, Akashi E, Kusaka T, Chiba S: Seropositivity to Chlamydia trachomatis during pregnancy and perinatal complications. J Infect Chemother. 1998, 4: 28-31.CrossRef
14.
go back to reference Couroucli XI, Welty SE, Ramsay PL, Wearden ME, Fuentes-Garcia FJ, Ni J, Jacobs TN, Towbin JA, Bowles NE: Detection of microorganisms in the tracheal aspirates of preterm infants by polymerase chain reaction: association of adenovirus infection with bronchopulmonary dysplasia. Pediatr Res. 2000, 47: 225-32.CrossRefPubMed Couroucli XI, Welty SE, Ramsay PL, Wearden ME, Fuentes-Garcia FJ, Ni J, Jacobs TN, Towbin JA, Bowles NE: Detection of microorganisms in the tracheal aspirates of preterm infants by polymerase chain reaction: association of adenovirus infection with bronchopulmonary dysplasia. Pediatr Res. 2000, 47: 225-32.CrossRefPubMed
15.
go back to reference Numazaki K, Chiba S, Kogawa K, Umetsu M, Motoya H, Nakao T: Chronic respiratory disease in premature infants caused by Chlamydia trachomatis. J Clin Pathol. 1986, 39: 84-9.CrossRefPubMedPubMedCentral Numazaki K, Chiba S, Kogawa K, Umetsu M, Motoya H, Nakao T: Chronic respiratory disease in premature infants caused by Chlamydia trachomatis. J Clin Pathol. 1986, 39: 84-9.CrossRefPubMedPubMedCentral
16.
go back to reference Garland SM, Bowman ED: Role of Ureaplasma urealyticum and Chlamydia trachomatis. Pathology. 1996, 28: 266-9.CrossRefPubMed Garland SM, Bowman ED: Role of Ureaplasma urealyticum and Chlamydia trachomatis. Pathology. 1996, 28: 266-9.CrossRefPubMed
17.
go back to reference Da Silva O, Gregson D, Hammerberg O: Role of Ureaplasma urealyticum and Chlamydia trachomatis in development of bronchopulmonary dysplasia in very low birth weight infants. Pediatr Infect Dis J. 1997, 16: 364-9. 10.1097/00006454-199704000-00006.CrossRefPubMed Da Silva O, Gregson D, Hammerberg O: Role of Ureaplasma urealyticum and Chlamydia trachomatis in development of bronchopulmonary dysplasia in very low birth weight infants. Pediatr Infect Dis J. 1997, 16: 364-9. 10.1097/00006454-199704000-00006.CrossRefPubMed
18.
go back to reference Numazaki K: Oculogenital transmission of Chlamydia trachomatis. Int Med J. 2000, 7: 61-2. Numazaki K: Oculogenital transmission of Chlamydia trachomatis. Int Med J. 2000, 7: 61-2.
19.
go back to reference Numazaki K, Niida Y, Chiba S: Antigen detection of Chlamydia trachomatis from the endocervix is not enough for screening of perinatal complications. Am J Obstet Gynecol. 1997, 176: 951-2.CrossRefPubMed Numazaki K, Niida Y, Chiba S: Antigen detection of Chlamydia trachomatis from the endocervix is not enough for screening of perinatal complications. Am J Obstet Gynecol. 1997, 176: 951-2.CrossRefPubMed
20.
go back to reference Nyari T, Woodward M, Meszaros G, Karsai J, Kovacs L: Chlamydia trachomatis infection and the risk of perinatal mortality in Hungary. J Perinat Med. 2001, 29: 55-59.CrossRefPubMed Nyari T, Woodward M, Meszaros G, Karsai J, Kovacs L: Chlamydia trachomatis infection and the risk of perinatal mortality in Hungary. J Perinat Med. 2001, 29: 55-59.CrossRefPubMed
21.
go back to reference Numazaki K: Current problems of Chlamydia trachomatis infections in Japan. Int Med J. 1999, 6: 69-74. Numazaki K: Current problems of Chlamydia trachomatis infections in Japan. Int Med J. 1999, 6: 69-74.
Metadata
Title
Chlamydia trachomatisinfection in early neonatal period
Publication date
01-12-2003
Published in
BMC Infectious Diseases / Issue 1/2003
Electronic ISSN: 1471-2334
DOI
https://doi.org/10.1186/1471-2334-3-2

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