Published in:
Open Access
01-05-2014 | Poster presentation
HIV-associated Burkitt lymphoma with bone marrow and cerebral invasion in a patient with history of Plasmodium falciparum infection
Authors:
Irina Lăpădat, Cristina Popescu, Raluca Dulamă, Alina Lobodan, Anca Ruxandra Negru, Mihaela Rădulescu, Violeta Molagic, Ruxandra Moroti, Cătălin Tilişcan, Victoria Aramă
Published in:
BMC Infectious Diseases
|
Special Issue 4/2014
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Excerpt
HIV infected patients are more likely to develop non-Hodgkin lymphoma (NHL). Burkitt lymphoma (BL) is a highly aggressive NHL, associated with immunosuppression, especially with HIV. According to WHO classification there are three clinical types of BL: endemic, sporadic and immunosuppression-associated. Sporadic lymphoma was described especially in children (40% of child lymphomas in USA and EU). Two cofactors seem to be associated with BL: Ebstein Barr virus (EBV) and Plasmodium falciparum (PF) infection. PF and EBV are well-known co-factors in the pathogenesis of BL, but the mechanisms of interaction remain unclear. …
