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Published in: BMC Infectious Diseases 3/2014

Open Access 01-05-2014 | Poster presentation

Homozygous KIR2DL3 confers susceptibility to tuberculosis infection in HIV seropositive individuals

Authors: Stalinraja Maruthamuthu, Suresh Madasamy, Jayalakshmi Mariakuttikan

Published in: BMC Infectious Diseases | Special Issue 3/2014

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Excerpt

Tuberculosis (TB) remains an important cause of death among patients infected with HIV. Genetic variation influences differential development of TB particularly in Immunosupressed patients. Natural Killer cells play an important role in the innate immune system by providing the first line of defence against viral infections and tumors. Their activity is partially controlled by distinct inhibitory and activating killer Ig like receptors (KIR) that recognize specific ligands on potential target cells. Objective of this study is to determine the association between KIR and HIV co-infection. …
Metadata
Title
Homozygous KIR2DL3 confers susceptibility to tuberculosis infection in HIV seropositive individuals
Authors
Stalinraja Maruthamuthu
Suresh Madasamy
Jayalakshmi Mariakuttikan
Publication date
01-05-2014
Publisher
BioMed Central
Published in
BMC Infectious Diseases / Issue Special Issue 3/2014
Electronic ISSN: 1471-2334
DOI
https://doi.org/10.1186/1471-2334-14-S3-P67

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