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Published in: BMC Infectious Diseases 3/2014

Open Access 01-05-2014 | Poster presentation

Hepatitis C virus infection contributes to impregnation of markers of immune inhibition: potential preludes underlying viral latency and persistence

Authors: Muttiah Barathan, Mohamed Rosmawati, Jamuna Vadivelu, Marie Larsson, Vijayakumar Velu, Saeidi Alireza, Li Yen Chang, Esaki Muthu Shankar

Published in: BMC Infectious Diseases | Special Issue 3/2014

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Excerpt

Hepatitis C virus (HCV) represents one of the persistent viral infections afflicting humankind, and a significant proportion of chronic HCV disease progresses over time through liver fibrosis, cirrhosis and hepatocellular carcinoma (HCC). One potential mechanism underlying the chronic disease is believed to be viral escape from immune surveillance via upregulation of inhibitory molecules on immune cells by HCV. We investigated the diverse expression of various inhibitory molecules in PBMCs of healthy non-HCV controls and chronically HCV infected patients. …
Metadata
Title
Hepatitis C virus infection contributes to impregnation of markers of immune inhibition: potential preludes underlying viral latency and persistence
Authors
Muttiah Barathan
Mohamed Rosmawati
Jamuna Vadivelu
Marie Larsson
Vijayakumar Velu
Saeidi Alireza
Li Yen Chang
Esaki Muthu Shankar
Publication date
01-05-2014
Publisher
BioMed Central
Published in
BMC Infectious Diseases / Issue Special Issue 3/2014
Electronic ISSN: 1471-2334
DOI
https://doi.org/10.1186/1471-2334-14-S3-P3

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