Published in:
Open Access
01-05-2014 | Oral presentation
Expression of the human microRNA miR 29a in an Indian cohort of HIV patients
Authors:
Rakesh Dey, Kartik Soni, Shanmugam Saravanan, Pachamuthu Balakrishnan, Vikram Kumar, Vinod Scaria, Beena Pillai, Suniti Solomon, Samir K Brahmachari
Published in:
BMC Infectious Diseases
|
Special Issue 3/2014
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Excerpt
The events during host virus interaction pave the way to differential outcomes in HIV-1 disease progression rates. We have earlier shown that HIV-1Nef gene harbors target sites for the human microRNA, miRNA 29a/b. Over expression of miR 29a/b could reduce virus levels by targeting the Nef gene. We hypothesized that differential expression of the microRNA maybe a protective factor in AIDS progression. …