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Published in: BMC Infectious Diseases 3/2014

Open Access 01-05-2014 | Oral presentation

The frequencies of naturally occurring protease inhibitor resistance mutations in HIV proviral sequences of drug naïve sex workers in Nairobi, Kenya and their correlation with host immune response driven positively selected mutations in HIV-1

Authors: Raghavan Sampathkumar, Elnaz Shadabi, David La, John Ho, Binhua Liang, Joshua Kimani, Francis A Plummer, Ma Luo

Published in: BMC Infectious Diseases | Special Issue 3/2014

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Excerpt

Sub Saharan Africa accounts for 69% of the people living with HIV globally. Antiretroviral therapy (ART) has saved 9 million life years in Sub Saharan Africa. However, drug resistance mutations reduce the effectiveness of ART, and need to be monitored for effective ART. Naturally occurring primary antiretroviral drug resistance mutations have not been well analyzed in ART naïve HIV+ patients from Kenya. …
Metadata
Title
The frequencies of naturally occurring protease inhibitor resistance mutations in HIV proviral sequences of drug naïve sex workers in Nairobi, Kenya and their correlation with host immune response driven positively selected mutations in HIV-1
Authors
Raghavan Sampathkumar
Elnaz Shadabi
David La
John Ho
Binhua Liang
Joshua Kimani
Francis A Plummer
Ma Luo
Publication date
01-05-2014
Publisher
BioMed Central
Published in
BMC Infectious Diseases / Issue Special Issue 3/2014
Electronic ISSN: 1471-2334
DOI
https://doi.org/10.1186/1471-2334-14-S3-O2

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