Published in:
Open Access
01-05-2014 | Oral presentation
The frequencies of naturally occurring protease inhibitor resistance mutations in HIV proviral sequences of drug naïve sex workers in Nairobi, Kenya and their correlation with host immune response driven positively selected mutations in HIV-1
Authors:
Raghavan Sampathkumar, Elnaz Shadabi, David La, John Ho, Binhua Liang, Joshua Kimani, Francis A Plummer, Ma Luo
Published in:
BMC Infectious Diseases
|
Special Issue 3/2014
Login to get access
Excerpt
Sub Saharan Africa accounts for 69% of the people living with HIV globally. Antiretroviral therapy (ART) has saved 9 million life years in Sub Saharan Africa. However, drug resistance mutations reduce the effectiveness of ART, and need to be monitored for effective ART. Naturally occurring primary antiretroviral drug resistance mutations have not been well analyzed in ART naïve HIV+ patients from Kenya. …