Published in:
Open Access
01-05-2014 | ePoster presentation
Longer sequence insertions in p6 gag play a role in immune escape in HIV-1 subtype C
Authors:
Shilpee Sharma, GA Shambhu Prasad, Ravi Vijaya Satya, Viswanath Ragupathy, Shanmugam Saravanan, Kailapuri G Murugavel, Pachamuthu Balakrishnan, Suniti Solomon, Indira Hewlett, Udaykumar Ranga
Published in:
BMC Infectious Diseases
|
Special Issue 3/2014
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Excerpt
HIV-1 is capable of evading the CTL immune response by introducing mutations in residues both within the epitopes and in sequences flanking the epitopes. The present study aims at identifying the mechanisms of CTL immune escape primarily in the asymptomatic phase of HIV-1 subtype C in drug naive patients from an Indian clinical cohort. …