Published in:
Open Access
01-05-2014 | ePoster presentation
Synthesis of biogenic gold nano conjugate for increased efficacy and sustained drug release profile of saquinavir
Authors:
Rohan Kesarkar, Sweta Kothari, Abhay Chowdhary
Published in:
BMC Infectious Diseases
|
Special Issue 3/2014
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Excerpt
Conventional anti retroviral treatment (ART) has been a core treatment for HIV over the past three decades. Despite the effectiveness of these drugs, most of them abide significant drawbacks such as poor bioavailability and undesirable side effects; thus reducing patient compliance and rendering treatment regime ineffective. This research work is an attempt to develop a dual pronged carrier system using gold nanoparticles (GNP) for increasing effectiveness and sustained drug release of saquinavir. …