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BMC Infectious Diseases
Published in: BMC Infectious Diseases 3/2014

Open Access 01-05-2014 | ePoster presentation

Development of dual inhibitors targeting DprE1 and AHAS for treatment of Mycobacterium tuberculosis infection

Authors: Rupesh V Chikhale, Amit M Pant, Sunil S Menghani, Pramod B Khedekar

Published in: BMC Infectious Diseases | Special Issue 3/2014

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Excerpt

The emerging multidrug resistant (MDR) and extensively drug resistant (XDR) Mycobacterium tuberculosis (MTB) infection is increasing with greater complexity, estimated 220000-400000 tuberculosis cases emerged in 2011 globally. A number of lead compounds have been developed for treatment of MDR and XDR TB, but no new chemical entity has emerged for clinical use. Recently DprE1 and AHAS have been identified as promising drug targets. …
Metadata
Title
Development of dual inhibitors targeting DprE1 and AHAS for treatment of Mycobacterium tuberculosis infection
Authors
Rupesh V Chikhale
Amit M Pant
Sunil S Menghani
Pramod B Khedekar
Publication date
01-05-2014
Publisher
BioMed Central
Published in
BMC Infectious Diseases / Issue Special Issue 3/2014
Electronic ISSN: 1471-2334
DOI
https://doi.org/10.1186/1471-2334-14-S3-E24

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