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BMC Infectious Diseases
Published in: BMC Infectious Diseases 3/2014

Open Access 01-05-2014 | ePoster presentation

Mycobacterium bovis Bacille Calmette-Guerin infection modulates GRK2/3 dependent cytokine secretion

Authors: Manisha Yadav, D Nagarjuna, Rakesh Singh Dhanda

Published in: BMC Infectious Diseases | Special Issue 3/2014

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Excerpt

Mycobacterium tuberculosis has evolved highly specialized mechanisms to proliferate in the host during infection. In this process, the infection of alveolar epithelial cells is a necessary step for mycobacteria dissemination; however the mechanisms of mycobacterial epithelial interactions are incompletely understood. Previously, we characterized the role of epithelial G protein coupled receptors (GPCR) CXCR1 and CXCR2 during mycobacterial infection. However the role of GPCR kinases (GRK) 2/3 and GRK4-6 in response to mycobacterial infection has not been investigated. …
Metadata
Title
Mycobacterium bovis Bacille Calmette-Guerin infection modulates GRK2/3 dependent cytokine secretion
Authors
Manisha Yadav
D Nagarjuna
Rakesh Singh Dhanda
Publication date
01-05-2014
Publisher
BioMed Central
Published in
BMC Infectious Diseases / Issue Special Issue 3/2014
Electronic ISSN: 1471-2334
DOI
https://doi.org/10.1186/1471-2334-14-S3-E20

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