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BMC Infectious Diseases
Published in: BMC Infectious Diseases 3/2014

Open Access 01-05-2014 | ePoster presentation

Design, synthesis and biological evaluation on N- heteroaryl compounds as probable NNRTIs against laboratory adapted strains and the primary isolates of HIV-1

Authors: Anuradha Singh, Madhu Yadav, Ritika Srivastava, Nidhi Singh, Ashwini Godse, Rahul Suryawanshi, Ashwini Dhamanage, Smita Kulkarni, Ramendra K Singh

Published in: BMC Infectious Diseases | Special Issue 3/2014

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Excerpt

The emergence of drug resistant HIV strains and suitability of NNRTIs as potent anti-HIV molecules used in HAART did attract our attention towards developing NNRTIs. We, therefore, focused on developing some new NNRTIs utilizing benzimidazole and pyrimidine moieties to match the hydrophobic nature of the allosteric pocket in HIV-RT. …
Metadata
Title
Design, synthesis and biological evaluation on N- heteroaryl compounds as probable NNRTIs against laboratory adapted strains and the primary isolates of HIV-1
Authors
Anuradha Singh
Madhu Yadav
Ritika Srivastava
Nidhi Singh
Ashwini Godse
Rahul Suryawanshi
Ashwini Dhamanage
Smita Kulkarni
Ramendra K Singh
Publication date
01-05-2014
Publisher
BioMed Central
Published in
BMC Infectious Diseases / Issue Special Issue 3/2014
Electronic ISSN: 1471-2334
DOI
https://doi.org/10.1186/1471-2334-14-S3-E15

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