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Published in: BMC Geriatrics 1/2010

Open Access 01-12-2010 | Research article

Impact of valvular heart disease on activities of daily living of nonagenarians: the leiden 85-plus study a population based study

Authors: Thomas van Bemmel, Victoria Delgado, Jeroen J Bax, Jacobijn Gussekloo, Gerard J Blauw, Rudi G Westendorp, Eduard R Holman

Published in: BMC Geriatrics | Issue 1/2010

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Abstract

Background

Data on the prevalence of valvular heart disease in very old individuals are scarce and based mostly on in-hospital series. In addition, the potential detrimental effect of valvular heart disease on the activities of daily living is unknown. The present study evaluated the prevalence of significant valvular heart disease and the impact of valvular heart disease on the activities of daily living in community dwelling nonagenarians. Nested within the Leiden 85-plus study, a population based follow-up study of the oldest old, a sample of 81 nonagenarians was recruited.

Methods

The left ventricular (LV) dimensions, function and the presence and severity of heart valvular disease were evaluated by echocardiography. Significant valvular heart disease included any mitral or aortic stenosis severity, moderate or severe mitral regurgitation, moderate or severe aortic regurgitation and moderate or severe tricuspid regurgitation. Activities of daily living were assessed using the Groningen Activity Restriction Scale (GARS).

Results

LV cavity diameters (end-diastolic diameter 47 ± 8 mm, end-systolic diameter 30 ± 8 mm) and systolic LV function (LV ejection fraction 66 ± 13%) were within normal for the majority of the participants. Significant valvular disease was present in 57 (70%) individuals, with mitral regurgitation and aortic regurgitation as the most frequent valve diseases (49% and 28% respectively). The GARS score between individuals with and without significant valvular heart disease was similar (36.2 ± 9.2 vs. 34.4 ± 13.2, p = 0.5).

Conclusions

Nonagenarian, outpatient individuals have a high prevalence of significant valvular heart disease. However, no relation was observed between the presence of significant valvular heart disease and the ability to perform activities of daily living.
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Metadata
Title
Impact of valvular heart disease on activities of daily living of nonagenarians: the leiden 85-plus study a population based study
Authors
Thomas van Bemmel
Victoria Delgado
Jeroen J Bax
Jacobijn Gussekloo
Gerard J Blauw
Rudi G Westendorp
Eduard R Holman
Publication date
01-12-2010
Publisher
BioMed Central
Published in
BMC Geriatrics / Issue 1/2010
Electronic ISSN: 1471-2318
DOI
https://doi.org/10.1186/1471-2318-10-17

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