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BMC Primary Care
Published in: BMC Primary Care 1/2013

Open Access 01-12-2013 | Research article

Supporting smoking cessation in chronic obstructive pulmonary disease with behavioral intervention: a randomized controlled trial

Authors: Peian Lou, Yanan Zhu, Peipei Chen, Pan Zhang, Jiaxi Yu, Ning Zhang, Na Chen, Lei Zhang, Hongmin Wu, Jing Zhao

Published in: BMC Primary Care | Issue 1/2013

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Abstract

Background

Cigarette smoking is the major risk factor for chronic obstructive pulmonary disease (COPD). But a fewer smoking cessation measures were conducted in communities for smokers with COPD in China. The aim of our study was to assess the preventive effects of behavioral interventions for smoking cessation and potential impact factors in smokers with COPD in China.

Methods

In a randomised controlled smoking cessation trial 3562 patients with COPD who were current smoker were allocated to intervention group received behavioral intervention and control group received the usual care for two years. The primary efficacy endpoint was the complete and continuous abstinence from smoking from the beginning of month 24 to the end of month 30. Participants were followed up at month 48.

Results

Continuous smoking abstinence rates from month 24 to 30 were significantly higher in participants receiving behavioral intervention than in those receiving usual care (46.4% vs 3.4%, p < 0.001). Continuous abstinence rates from months 24 to 36 (45.8% vs 4.0%) and months 24 to 48 (44.3% vs 5.1%) were also higher in participants receiving behavioral intervention than in those control group. Family members or family physicians/nurses smoking were first identified to influence smoking cessation.

Conclusions

Behavioral intervention doubled the smoking cessation rate in patients with COPD and was complied well by the general practitioners. The family members and family physicians/nurses smoking were the main risk factors for smoking cessation.

Trial registration

Chinese Clinical Trials Registration (ChiCTR-TRC-12001958).
Appendix
Available only for authorised users
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Metadata
Title
Supporting smoking cessation in chronic obstructive pulmonary disease with behavioral intervention: a randomized controlled trial
Authors
Peian Lou
Yanan Zhu
Peipei Chen
Pan Zhang
Jiaxi Yu
Ning Zhang
Na Chen
Lei Zhang
Hongmin Wu
Jing Zhao
Publication date
01-12-2013
Publisher
BioMed Central
Published in
BMC Primary Care / Issue 1/2013
Electronic ISSN: 2731-4553
DOI
https://doi.org/10.1186/1471-2296-14-91

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