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The Journal of Headache and Pain
Published in: The Journal of Headache and Pain 1/2014

Open Access 01-12-2014 | Meeting abstract

EHMTI-0062. Expression of fractalkine (CX3CL1) and fractalkine receptor (CX3CR1) in the trigeminal ganglia: implications for craniofacial nociception

Authors: P Gazerani, BE Cairns, XD Dong

Published in: The Journal of Headache and Pain | Special Issue 1/2014

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Excerpt

Evidence indicates that fractalkine (CX3CL1) and its receptor CX3CR1 are involved in the pathogenesis of pain. Within the central nervous system, CX3CL1 is expressed by neurons and CX3CR1 by microglia. This unique pattern of expression has supported the idea of neuron to glia communication, which is thought to be disregulated under pathological pain conditions. The presence of CX3CL1 and CX3CR1 in trigeminal ganglion (TG) neurons and satellite glial cells (SGCs) and their contribution to nociceptive signal transmission have not been well documented. …
Metadata
Title
EHMTI-0062. Expression of fractalkine (CX3CL1) and fractalkine receptor (CX3CR1) in the trigeminal ganglia: implications for craniofacial nociception
Authors
P Gazerani
BE Cairns
XD Dong
Publication date
01-12-2014
Publisher
Springer Milan
Published in
The Journal of Headache and Pain / Issue Special Issue 1/2014
Print ISSN: 1129-2369
Electronic ISSN: 1129-2377
DOI
https://doi.org/10.1186/1129-2377-15-S1-F7

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