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Allergy, Asthma & Clinical Immunology
Published in: Allergy, Asthma & Clinical Immunology 1/2021

01-12-2021 | Coronavirus | Short report

Asthma and COVID-19: a systematic review

Authors: Natália F. Mendes, Carlos P. Jara, Eli Mansour, Eliana P. Araújo, Licio A. Velloso

Published in: Allergy, Asthma & Clinical Immunology | Issue 1/2021

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Abstract

Background

Severe coronavirus disease-19 (COVID-19) presents with progressive dyspnea, which results from acute lung inflammatory edema leading to hypoxia. As with other infectious diseases that affect the respiratory tract, asthma has been cited as a potential risk factor for severe COVID-19. However, conflicting results have been published over the last few months and the putative association between these two diseases is still unproven.

Methods

Here, we systematically reviewed all reports on COVID-19 published since its emergence in December 2019 to June 30, 2020, looking into the description of asthma as a premorbid condition, which could indicate its potential involvement in disease progression.

Results

We found 372 articles describing the underlying diseases of 161,271 patients diagnosed with COVID-19. Asthma was reported as a premorbid condition in only 2623 patients accounting for 1.6% of all patients.

Conclusions

As the global prevalence of asthma is 4.4%, we conclude that either asthma is not a premorbid condition that contributes to the development of COVID-19 or clinicians and researchers are not accurately describing the premorbidities in COVID-19 patients.
Appendix
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Metadata
Title
Asthma and COVID-19: a systematic review
Authors
Natália F. Mendes
Carlos P. Jara
Eli Mansour
Eliana P. Araújo
Licio A. Velloso
Publication date
01-12-2021
Publisher
BioMed Central
Published in
Allergy, Asthma & Clinical Immunology / Issue 1/2021
Electronic ISSN: 1710-1492
DOI
https://doi.org/10.1186/s13223-020-00509-y

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