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Published in: The Ultrasound Journal 1/2022

Open Access 01-12-2022 | Ultrasound | Original article

Ultrasonographic evaluation of deep vein thrombosis related to the central catheter in hemodialytic patients

Authors: Ana Luisa Silveira Vieira, José Muniz Pazeli Júnior, Andrea Silva Matos, Andreza Marques Pereira, Izadora Rezende Pinto, Letícia Esteves de Oliveira Silva, Letícia Siqueira Guilherme, Sofia Laura Archângelo e Silva

Published in: The Ultrasound Journal | Issue 1/2022

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Abstract

Background

Point of care ultrasound (PoCUS) is a useful tool for the early diagnosis of thrombosis related to the central venous catheter for dialysis (TR-CVCd). However, the application of PoCUS is still not common as a bedside imaging examination and TR-CVCd remains often underdiagnosed in the routine practice. The aim of this study was to investigate if a compression technique for the diagnosis of TR-CVCd blindly performed by PoCUS experts and medical students is accurate when compared to a Doppler study.

Methods

Two medical students without prior knowledge in PoCUS received a short theoretical–practical training to evaluate TR-CVCd of the internal jugular vein by means of the ultrasound compression technique. After the training phase, patients with central venous catheter for dialysis (CVCd) were evaluated by the students in a private hemodialysis clinic. The results were compared to those obtained on the same population by doctors with solid experience in PoCUS, using both the compression technique and the color Doppler.

Results

Eighty-one patients were eligible for the study and the prevalence of TR-CVCd diagnosed by Doppler was 28.4%. The compression technique performed by the students and by experts presented, respectively, a sensitivity of 59.2% (CI 51.6–66.8) vs 100% and a specificity of 89.6% (CI 84.9–94.3) vs 94.8% (CI 91.4–98.2).

Conclusion

The compression technique in the hands of PoCUS experts demonstrated high accuracy in the diagnosis of TR-CVCd and should represent a standard in the routine examination of dialytic patients. The training of PoCUS inexperienced students for the diagnosis of TR-CVCd is feasible but did not lead to a sufficient level of sensitivity.
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Literature
1.
go back to reference Levin A, Tonelli M, Bonventre J, Coresh J, Donner J, Fogo AB, Fox CS, Gansevoort RT, Heerspink HJL, Jardine M, Kasiske B, Köttgen A, Kretzler M, Levey AS, Luyckx VA, Mehta R, Moe O, Obrador G, Pannu N, Parikh C, Perkovic V, Pollock C, Stenvinkel P, Tuttle KR, Wheeler DC, Eckardt KU (2017) A roadmap for closing gaps in care, research, and policy. Lancet 390(10105):1888–1917CrossRef Levin A, Tonelli M, Bonventre J, Coresh J, Donner J, Fogo AB, Fox CS, Gansevoort RT, Heerspink HJL, Jardine M, Kasiske B, Köttgen A, Kretzler M, Levey AS, Luyckx VA, Mehta R, Moe O, Obrador G, Pannu N, Parikh C, Perkovic V, Pollock C, Stenvinkel P, Tuttle KR, Wheeler DC, Eckardt KU (2017) A roadmap for closing gaps in care, research, and policy. Lancet 390(10105):1888–1917CrossRef
2.
go back to reference Linardi F (2013) The importance of vascular access for hemodialysis in Brazil. J vasc bras 12(4):261–263CrossRef Linardi F (2013) The importance of vascular access for hemodialysis in Brazil. J vasc bras 12(4):261–263CrossRef
3.
go back to reference Ethier J, Mendelssohn DC, Elder SJ, Hasegawa T, Akizawa T, Akiba T, Canaud BJ, Pisoni RL (2008) Vascular access use and outcomes: an international perspective from the Dialysis Outcomes and Practice Patterns Study. Nephrol Dial Transplant 23(10):3219–3226CrossRef Ethier J, Mendelssohn DC, Elder SJ, Hasegawa T, Akizawa T, Akiba T, Canaud BJ, Pisoni RL (2008) Vascular access use and outcomes: an international perspective from the Dialysis Outcomes and Practice Patterns Study. Nephrol Dial Transplant 23(10):3219–3226CrossRef
4.
go back to reference Lok CE (2007) Fistula first initiative: advantages and pitfalls. Clin J Am Soc Nephrol 2(5):1043–1053CrossRef Lok CE (2007) Fistula first initiative: advantages and pitfalls. Clin J Am Soc Nephrol 2(5):1043–1053CrossRef
5.
go back to reference Lok CE, Foley R (2013) Vascular access morbidity and mortality: trends of the last decade. Clin J Am Soc Nephrol 8(7):1213–1219CrossRef Lok CE, Foley R (2013) Vascular access morbidity and mortality: trends of the last decade. Clin J Am Soc Nephrol 8(7):1213–1219CrossRef
6.
go back to reference Agraharkar M, Isaacson S, Mendelssohn D, Muralidharan J, Mustata S, Zevallos G, Besley M, Uldall R (1995) Percutaneously inserted silastic jugular hemodialysis catheters seldom cause jugular vein thrombosis. ASAIO J 41(2):169–172CrossRef Agraharkar M, Isaacson S, Mendelssohn D, Muralidharan J, Mustata S, Zevallos G, Besley M, Uldall R (1995) Percutaneously inserted silastic jugular hemodialysis catheters seldom cause jugular vein thrombosis. ASAIO J 41(2):169–172CrossRef
7.
go back to reference Karnik R, Valentin A, Winkler WB, Donath P, Slany J (1993) Duplex sonographic detection of internal jugular venous thrombosis after removal of central venous catheters. Clin Cardiol 16(1):26–29CrossRef Karnik R, Valentin A, Winkler WB, Donath P, Slany J (1993) Duplex sonographic detection of internal jugular venous thrombosis after removal of central venous catheters. Clin Cardiol 16(1):26–29CrossRef
8.
go back to reference Lee JA, Zierler BK, Zierler RE (2012) The risk factors and clinical outcomes of upper extremity deep vein thrombosis. Vasc Endovascular Surg 46(2):139–144CrossRef Lee JA, Zierler BK, Zierler RE (2012) The risk factors and clinical outcomes of upper extremity deep vein thrombosis. Vasc Endovascular Surg 46(2):139–144CrossRef
9.
go back to reference Gunawansa N, Sudusinghe DH, Wijayaratne DR (2018) Hemodialysis catheter-related central venous thrombosis: clinical approach to evaluation and management. Ann Vasc Surg 51:298–305CrossRef Gunawansa N, Sudusinghe DH, Wijayaratne DR (2018) Hemodialysis catheter-related central venous thrombosis: clinical approach to evaluation and management. Ann Vasc Surg 51:298–305CrossRef
10.
go back to reference Nunes AA, PazeliJúnior JM, Rodrigues AT, Tollendal AL, Ezequiel Oda S, Colugnati FAB, Bastos MG (2016) Development of skills to utilize point-of-care ultrasonography in nephrology practice. J Bras Nefrol 38(2):209–214CrossRef Nunes AA, PazeliJúnior JM, Rodrigues AT, Tollendal AL, Ezequiel Oda S, Colugnati FAB, Bastos MG (2016) Development of skills to utilize point-of-care ultrasonography in nephrology practice. J Bras Nefrol 38(2):209–214CrossRef
11.
go back to reference Hassanzadeh Rad A, Badeli H (2017) Point-of-care ultrasonography: is it time nephrologists were equipped with the 21th century’s stethoscope? Iran J Kidney Dis 11(4):259–262PubMed Hassanzadeh Rad A, Badeli H (2017) Point-of-care ultrasonography: is it time nephrologists were equipped with the 21th century’s stethoscope? Iran J Kidney Dis 11(4):259–262PubMed
12.
go back to reference Niyyar VD, O’Neill WC (2018) Point-of-care ultrasound in the practice of nephrology. Kidney Int 93(5):1052–1059CrossRef Niyyar VD, O’Neill WC (2018) Point-of-care ultrasound in the practice of nephrology. Kidney Int 93(5):1052–1059CrossRef
13.
go back to reference Silva RS, Paes AT (2012) Por dentro da estatística. Educ Contin Saúde Einstein 10(04):165–166 Silva RS, Paes AT (2012) Por dentro da estatística. Educ Contin Saúde Einstein 10(04):165–166
14.
go back to reference Sehgal AR, Snow RJ, Singer ME, Amini SB, DeOreo PB, Silver MR, Cebul RD (1998) Barriers to adequate delivery of hemodialysis. Am J Kidney Dis 31(4):593–601CrossRef Sehgal AR, Snow RJ, Singer ME, Amini SB, DeOreo PB, Silver MR, Cebul RD (1998) Barriers to adequate delivery of hemodialysis. Am J Kidney Dis 31(4):593–601CrossRef
15.
go back to reference Prandoni P, Polistena P, Bernardi E, Cogo A, Casara D, Verlato F, Angelini F, Simioni P, Signorini GP, Benedetti L, Girolami A (1997) Upper-extremity deep vein thrombosis. Risk factors, diagnosis, and complications. Arch Intern Med 157(1):57–62CrossRef Prandoni P, Polistena P, Bernardi E, Cogo A, Casara D, Verlato F, Angelini F, Simioni P, Signorini GP, Benedetti L, Girolami A (1997) Upper-extremity deep vein thrombosis. Risk factors, diagnosis, and complications. Arch Intern Med 157(1):57–62CrossRef
16.
go back to reference Yardim H, Erkoc R, Soyoral YU, Begenik H, Avcu S (2012) Assessment of internal jugular vein thrombosis due to central venous catheter in hemodialysis patients: a retrospective and prospective serial evaluation with ultrasonography. Clin Appl Thromb Hemost 18(6):662–665CrossRef Yardim H, Erkoc R, Soyoral YU, Begenik H, Avcu S (2012) Assessment of internal jugular vein thrombosis due to central venous catheter in hemodialysis patients: a retrospective and prospective serial evaluation with ultrasonography. Clin Appl Thromb Hemost 18(6):662–665CrossRef
17.
go back to reference Wilkin TD, Kraus MA, Lane KA, Trerotola SO (2003) Internal jugular vein thrombosis associated with hemodialysis catheters. Radiology 228(3):697–700CrossRef Wilkin TD, Kraus MA, Lane KA, Trerotola SO (2003) Internal jugular vein thrombosis associated with hemodialysis catheters. Radiology 228(3):697–700CrossRef
18.
go back to reference Pazeli JM Jr, Vieira ALS, Vicentino RS, Pazeli LJ, Lemos BC, Saliba MMR, Mello PA, Costa MD (2018) Point-of-care ultrasound evaluation and puncture simulation of the internal jugular vein by medical students. Crit Ultrasound J 10(1):34CrossRef Pazeli JM Jr, Vieira ALS, Vicentino RS, Pazeli LJ, Lemos BC, Saliba MMR, Mello PA, Costa MD (2018) Point-of-care ultrasound evaluation and puncture simulation of the internal jugular vein by medical students. Crit Ultrasound J 10(1):34CrossRef
19.
go back to reference Brass P, Hellmich M, Kolodziej L, Schick G, Smith AF (2015) Ultrasound guidance versus anatomical landmarks for internal jugular vein catheterization. Cochrane Database Syst Rev 1(1):CD006962PubMed Brass P, Hellmich M, Kolodziej L, Schick G, Smith AF (2015) Ultrasound guidance versus anatomical landmarks for internal jugular vein catheterization. Cochrane Database Syst Rev 1(1):CD006962PubMed
Metadata
Title
Ultrasonographic evaluation of deep vein thrombosis related to the central catheter in hemodialytic patients
Authors
Ana Luisa Silveira Vieira
José Muniz Pazeli Júnior
Andrea Silva Matos
Andreza Marques Pereira
Izadora Rezende Pinto
Letícia Esteves de Oliveira Silva
Letícia Siqueira Guilherme
Sofia Laura Archângelo e Silva
Publication date
01-12-2022
Publisher
Springer International Publishing
Published in
The Ultrasound Journal / Issue 1/2022
Electronic ISSN: 2524-8987
DOI
https://doi.org/10.1186/s13089-021-00252-4

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