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World Journal of Surgical Oncology
Published in: World Journal of Surgical Oncology 1/2023

Open Access 01-12-2023 | Neuroblastoma | Research

Safety and feasibility of laparoscopic resection of abdominal neuroblastoma without image-defined risk factors: a single-center experience

Authors: Saishuo Chang, Yu Lin, Shen Yang, Wei Yang, Haiyan Cheng, Xiaofeng Chang, Zhiyun Zhu, Jun Feng, Jianyu Han, Qinghua Ren, Huanmin Wang, Hong Qin

Published in: World Journal of Surgical Oncology | Issue 1/2023

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Abstract

Objective

To explore the criteria, safety and efficacy of laparoscopic surgery in pediatric neuroblastoma (NB).

Methods

A retrospective study of 87 patients with NB without image-defined risk factors (IDRFs) between December 2016 and January 2021 at Beijing Children’s Hospital was conducted. Patients were divided into two groups according to the surgical procedure.

Results

Between the 87 patients, there were 54 (62.07%) cases in the open surgery group and 33 (37.93%) cases in the laparoscopic surgery group. There were no significant differences between the two groups regarding demographic characteristics, genomic and biological features, operating time or postoperative complications. However, in terms of intraoperative bleeding (p = 0.013) and the time to start postoperative feeding after surgery (p = 0.002), the laparoscopic group was obviously better than the open group. Furthermore, there was no significant difference in the prognosis between the two groups, and no recurrence or death was observed.

Conclusion

For children with localized NB who have no IDRFs, laparoscopic surgery could be performed safely and effectively. Surgeons who are skilled in this can help children reduce surgical injuries, speed up postoperative recovery, and obtain the same prognosis as open surgery.
Appendix
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Metadata
Title
Safety and feasibility of laparoscopic resection of abdominal neuroblastoma without image-defined risk factors: a single-center experience
Authors
Saishuo Chang
Yu Lin
Shen Yang
Wei Yang
Haiyan Cheng
Xiaofeng Chang
Zhiyun Zhu
Jun Feng
Jianyu Han
Qinghua Ren
Huanmin Wang
Hong Qin
Publication date
01-12-2023
Publisher
BioMed Central
Published in
World Journal of Surgical Oncology / Issue 1/2023
Electronic ISSN: 1477-7819
DOI
https://doi.org/10.1186/s12957-023-02997-9

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