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World Journal of Surgical Oncology
Published in: World Journal of Surgical Oncology 1/2015

Open Access 01-12-2015 | Research

Prediction of T stage in gastric carcinoma by enhanced CT and oral contrast-enhanced ultrasonography

Authors: Tao Yu, Xinling Wang, Zilong Zhao, Fan Liu, Xiaoting Liu, Yan Zhao, Yahong Luo

Published in: World Journal of Surgical Oncology | Issue 1/2015

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Abstract

Background

The aim of this study is to explore the values of enhanced CT and oral contrast-enhanced ultrasonography on preoperative T stage in gastric carcinoma.

Methods

Forty patients with gastric carcinoma, including 27 males and 13 females, were confirmed by endoscopy, operation, and pathology. The median age of these patients was 49 years old (25 to 73 years). There were 19 cases of well-differentiated adenocarcinoma, 13 cases of poorly differentiated adenocarcinoma, 5 cases of signet ring cell carcinoma, and 4 cases of mucinous adenocarcinoma by pathology. All these patients were examined by both enhanced CT and ultrasound examination simultaneously 1 week before surgery. T staging in all these gastric carcinomas was carried out by enhanced CT or oral contrast-enhanced ultrasonography, respectively, or by both of them. The statistical difference between T stage by imaging and pathological T stage was analyzed.

Results

In this study, there were 5 cases with T1 stage, 9 cases with T2 stage, 20 cases with T3 stage, and 6 cases with T4 stage by pathology; 5 cases with T1 stage, 7 cases with T2 stage, 22 cases with T3 stage, and 6 cases with T4 stage by enhanced CT imaging with an accuracy of 75.00%; 6 cases with T1 stage, 7 cases with T2 stage, 22 cases with T3 stage, and 5 cases with T4 stage by ultrasonography examination, with an accuracy of 77.50%; and 4 cases with T1 stage, 10 cases with T2 stage, 19 cases with T3 stage, and 7 cases with T4 stage by both enhanced CT imaging and ultrasonography examination, with an accuracy of 85.00%. The accuracy of T staging in gastric carcinoma by both enhanced CT and ultrasound was higher than that either by enhanced CT or by ultrasound, respectively (P < 0.05). The anastomosis degree of the gastric carcinoma between enhanced CT and ultrasonography was κ = 0.404.

Conclusions

Combination diagnosis of enhanced CT and oral contrast-enhanced ultrasonography is helpful to improve the accuracy of T staging of gastric carcinoma before operations.
Literature
1.
Jemal A, Bray F, Center MM, Ferlay J, Ward E, Forman D. Global cancer statistics. CA Cancer J Clin. 2011;61:69–90.CrossRefPubMed
2.
Whiting J, Sano T, Saka M, Fukagawa T, Katai H, Sasako M. Follow-up of gastric cancer: a review. Gastric Cancer. 2006;9:74–81.CrossRefPubMed
3.
Ang J, Hu L, Huang PT, Wu JX, Huang LN, Cao CH, et al. Contrast-enhanced ultrasonography assessment of gastric cancer response to neoadjuvant chemotherapy. World J Gastroenterol. 2012;18:7026–32.CrossRefPubMedCentralPubMed
4.
Kutup A, Vashist YK, Groth S, Vettorazzi E, Yekebas EF, Soehendra N, et al. Endoscopic ultrasound staging in gastric cancer: does it help management decisions in the era of neoadjuvant treatment? Endoscopy. 2012;44:572–6.CrossRefPubMed
5.
6.
Kim HJ, Kim AY, Oh ST, Kim JS, Kim KW, Kim PN, et al. Gastric cancer staging at multi-detector row CT gastrography: comparison of transverse and volumetric CT scanning. Radiology. 2005;236:879–85.CrossRefPubMed
7.
Chen CY, Hsu JS, Wu DC, Kang WY, Hsieh JS, Jaw TS, et al. Gastric cancer: preoperative local staging with 3D multi-detector row CT–correlation with surgical and histopathologic results. Radiology. 2007;242:472–82.CrossRefPubMed
8.
Arocena MG, Barturen A, Bujanda L, Casado O, Ramirez MM, Oleagoitia JM, et al. MRI and endoscopic ultrasonography in the staging of gastric cancer. Rev Esp Enferm Dig. 2006;98:582–90.CrossRefPubMed
9.
10.
Meyer L, Meyer F, Schmidt U, Gastinger I, Lippert H. Endoscopic ultrasonography (EUS) in preoperative staging of gastric cancer–demand and reality. Pol Przegl Chir. 2012;84:152–7.PubMed
11.
Zheng Z, Yu Y, Lu M, Sun W, Wang F, Li P, et al. Double contrast-enhanced ultrasonography for the preoperative evaluation of gastric cancer: a comparison to endoscopic ultrasonography with respect to histopathology. Am J Surg. 2011;202:605–11.CrossRefPubMed
12.
Chen RJ, Huang PT, Li YP, Zheng ZQ, Zhao YP, Huang FG, et al. Comparison of preoperative T staging by oral contrast enhanced ultrasonography and double contrast enhanced ultrasonography in advanced gastric carcinoma. Zhonghua Zhong Liu Za Zhi. 2010;32:551–4.PubMed
13.
Wei F, Huang P, Li S, Chen J, Zhang Y, Hong Y, et al. Enhancement patterns of gastric carcinoma on contrast-enhanced ultrasonography: relationship with clinicopathological features. PLoS One. 2013;8:e73050.CrossRefPubMedCentralPubMed
14.
Wang CL, Yang YM, Cui J, Ouyang H, Wang ZM, Ye HS, et al. Diagnostic value of double contrast-enhanced ultrasonography in preoperative staging of gastric cancer. Zhonghua Zhong Liu Za Zhi. 2009;31:701–4.PubMed
15.
Carditello A, Scisca C, Stilo F, Parisi A, Basile M. The possible role of radiofrequency as complementary treatment of locally advanced gastric cancer. Ann Ital Chir. 2005;76:39–41.PubMed
16.
Caponigro F, Facchini G, Nasti G, Iaffaioli RV. Gastric cancer. Treatment of advanced disease and new drugs. Front Biosci. 2005;10:3122–6.CrossRefPubMed
17.
Hwang SW, Lee DH, Lee SH, Park YS, Hwang JH, Kim JW, et al. Preoperative staging of gastric cancer by endoscopic ultrasonography and multidetector-row computed tomography. J Gastroenterol Hepatol. 2010;25:512–8.CrossRefPubMed
18.
Seevaratnam R, Cardoso R, McGregor C, Lourenco L, Mahar A, Sutradhar R, et al. How useful is preoperative imaging for tumor, node, metastasis (TNM) staging of gastric cancer? A meta-analysis. Gastric Cancer. 2012;15 Suppl 1:S3–18.CrossRefPubMed
19.
Lee HS, Lee HE, Yang HK, Kim WH. Perigastric tumor deposits in primary gastric cancer: implications for patient prognosis and staging. Ann Surg Oncol. 2013;20:1604–13.CrossRefPubMed
20.
Zurleni T, Gjoni E, Ballabio A, Casieri R, Ceriani P, Marzoli L, et al. Sixth and seventh tumor-node-metastasis staging system compared in gastric cancer patients. World J Gastrointest Surg. 2013;5:287–93.CrossRefPubMedCentralPubMed
21.
Furukawa K, Miyahara R, Itoh A, Ohmiya N, Hirooka Y, Mori K, et al. Diagnosis of the invasion depth of gastric cancer using MDCT with virtual gastroscopy: comparison with staging with endoscopic ultrasound. AJR Am J Roentgenol. 2011;197:867–75.CrossRefPubMed
22.
Badea R, Neciu C, Iancu C, Al Hajar N, Pojoga C, Botan E. The role of i.v. and oral contrast enhanced ultrasonography in the characterization of gastric tumors. A preliminary study. Med Ultrason. 2012;14:197–203.PubMed
23.
Parente F, Greco S, Molteni M, Anderloni A, Sampietro GM, Danelli PG, et al. Oral contrast enhanced bowel ultrasonography in the assessment of small intestine Crohn’s disease. A prospective comparison with conventional ultrasound, x ray studies, and ileocolonoscopy. Gut. 2004;53:1652–7.CrossRefPubMedCentralPubMed
24.
Minami M, Kawauchi N, Itai Y, Niki T, Sasaki Y. Gastric tumors: radiologic-pathologic correlation and accuracy of T staging with dynamic CT. Radiology. 1992;185:173–8.CrossRefPubMed
25.
Kadowaki K, Murakami T, Yoshioka H, Kim T, Takahashi S, Tomoda K, et al. Helical CT imaging of gastric cancer: normal wall appearance and the potential for staging. Radiat Med. 2000;18:47–54.PubMed
26.
Hizawa K, Iwai K, Esaki M, Matsumoto T, Suekane H, Iida M. Is endoscopic ultrasonography indispensable in assessing the appropriateness of endoscopic resection for gastric cancer? Endoscopy. 2002;34:973–8.CrossRefPubMed
27.
Li S, Huang P, Wang Z, Chen J, Xu H, Wang L, et al. Preoperative T staging of advanced gastric cancer using double contrast-enhanced ultrasound. Ultraschall Med. 2012;33:E218–24.CrossRefPubMed
28.
Venkataraman I, Rao HK, Singh P, Elangovan S, Kate V. Efficacy of hydrogastric sonography and spiral computed tomography in staging of gastric carcinoma–a comparative study. J Clin Ultrasound. 2010;38:480–5.CrossRefPubMed
Metadata
Title
Prediction of T stage in gastric carcinoma by enhanced CT and oral contrast-enhanced ultrasonography
Authors
Tao Yu
Xinling Wang
Zilong Zhao
Fan Liu
Xiaoting Liu
Yan Zhao
Yahong Luo
Publication date
01-12-2015
Publisher
BioMed Central
Published in
World Journal of Surgical Oncology / Issue 1/2015
Electronic ISSN: 1477-7819
DOI
https://doi.org/10.1186/s12957-015-0577-7

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