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Published in: Malaria Journal 1/2018

Open Access 01-12-2018 | Research

Evaluation of the long-term efficacy of K-Othrine® PolyZone on three surfaces against laboratory reared Anopheles gambiae in semi-field conditions

Authors: James C. Dunford, Alden S. Estep, Christy M. Waits, Alec G. Richardson, David F. Hoel, Karin Horn, Todd W. Walker, Jessika S. Blersch, Jerry D. Kerce, Robert A. Wirtz

Published in: Malaria Journal | Issue 1/2018

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Abstract

Background

In this semi-field study, a new polymer-enhanced deltamethrin formulation, K-Othrine® PolyZone, was compared to a standard deltamethrin product for residual activity against a susceptible strain of laboratory-reared Anopheles gambiae using standard WHO cone bioassays.

Methods

Residual insecticide efficacy was recorded after exposure to metal, cement and wood panels maintained in experimental huts in sub-tropical environmental conditions in north central Florida, USA, and panels stored in a climate controlled chamber located at the Centers for Disease Control and Prevention, Georgia, USA.

Conclusions

K-Othrine® PolyZone demonstrated 100% control on metal and cement panels 1 year post application and > 80% control on wood panels up to 6 mo. The new formulation should be considered for use in indoor residual spray programmes requiring long-term control of malaria vectors.
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Literature
1.
go back to reference WHO. Indoor residual spraying: an operational manual for indoor residual spraying (IRS) for malaria transmission control and elimination. Geneva: World Health Organization; 2013. p. 109. WHO. Indoor residual spraying: an operational manual for indoor residual spraying (IRS) for malaria transmission control and elimination. Geneva: World Health Organization; 2013. p. 109.
2.
go back to reference Steinhardt LC, Adoke Y, Nasr S, Wiegand RE, Rubahika D, Serwanga A, et al. The effect of indoor residual spraying on malaria and anaemia in high transmission area of Northern Uganda. Am Trop Med Hyg. 2013;88:855–61.CrossRef Steinhardt LC, Adoke Y, Nasr S, Wiegand RE, Rubahika D, Serwanga A, et al. The effect of indoor residual spraying on malaria and anaemia in high transmission area of Northern Uganda. Am Trop Med Hyg. 2013;88:855–61.CrossRef
3.
go back to reference Evans MS, Noguchi GE, Rice CP. The biomagnification of polychlorinated biphenyls, Toxaphene, and DDT compounds in a Lake Michigan offshore food web. Arch Environ Contam Toxicol. 1991;20:87–93.CrossRefPubMed Evans MS, Noguchi GE, Rice CP. The biomagnification of polychlorinated biphenyls, Toxaphene, and DDT compounds in a Lake Michigan offshore food web. Arch Environ Contam Toxicol. 1991;20:87–93.CrossRefPubMed
4.
go back to reference Hemingway J, Hawkes NJ, McCarroll L, Ranson H. The molecular basis of insecticide resistance in mosquitoes. Insect Biochem Molec. 2004;34:653–65.CrossRef Hemingway J, Hawkes NJ, McCarroll L, Ranson H. The molecular basis of insecticide resistance in mosquitoes. Insect Biochem Molec. 2004;34:653–65.CrossRef
5.
go back to reference Mulamba C, Riveron JM, Ibrahim SS, Irving H, Barnes KG, Mukwaya LG, et al. Widespread pyrethroid and DDT resistance in the major malaria vector Anopheles funestus in East Africa is driven by metabolic resistance mechanisms. PLoS One. 2014;e110058. Mulamba C, Riveron JM, Ibrahim SS, Irving H, Barnes KG, Mukwaya LG, et al. Widespread pyrethroid and DDT resistance in the major malaria vector Anopheles funestus in East Africa is driven by metabolic resistance mechanisms. PLoS One. 2014;e110058.
6.
go back to reference WHO. World Malaria Report 2015. Geneva: World Health Organization; 2015. p. 280. WHO. World Malaria Report 2015. Geneva: World Health Organization; 2015. p. 280.
7.
go back to reference Aïkpon R, Agossa F, Ossè R, Oussou O, Aïzoun N, Oké-Agbo F, et al. Bendiocarb resistance in Anopheles gambiae s.l. populations from Atacora department in Benin, West Africa: a threat for malaria vector control. Parasit Vectors. 2013;192. Aïkpon R, Agossa F, Ossè R, Oussou O, Aïzoun N, Oké-Agbo F, et al. Bendiocarb resistance in Anopheles gambiae s.l. populations from Atacora department in Benin, West Africa: a threat for malaria vector control. Parasit Vectors. 2013;192.
8.
go back to reference Ossè R, Aïkpon R, Louis Gbédjissi G, Gnanguenon V, Sèzonlin M, Govoétchan R, et al. A shift from indoor residual spraying (IRS) with bendiocarb to long-lasting insecticidal (mosquito) nets (LLINs) associated with changes in malaria transmission indicators in pyrethroid resistance areas in Benin. Parasit Vectors. 2013;6:73.CrossRefPubMedPubMedCentral Ossè R, Aïkpon R, Louis Gbédjissi G, Gnanguenon V, Sèzonlin M, Govoétchan R, et al. A shift from indoor residual spraying (IRS) with bendiocarb to long-lasting insecticidal (mosquito) nets (LLINs) associated with changes in malaria transmission indicators in pyrethroid resistance areas in Benin. Parasit Vectors. 2013;6:73.CrossRefPubMedPubMedCentral
9.
go back to reference WHO. Test procedures for insecticide resistance monitoring in malaria vectors, bio-efficacy and persistence of insecticides on treated surfaces. Geneva: World Health Organization; 1998. p. 1–46. WHO. Test procedures for insecticide resistance monitoring in malaria vectors, bio-efficacy and persistence of insecticides on treated surfaces. Geneva: World Health Organization; 1998. p. 1–46.
10.
go back to reference Sibanda MM, Focke WW, Labuschagne FJWJ, Moyo L, Nhlapo NS, Maity A, et al. Degradation of insecticides used for indoor spraying in malaria control and possible solutions. Malar J. 2011;10:307.CrossRefPubMedPubMedCentral Sibanda MM, Focke WW, Labuschagne FJWJ, Moyo L, Nhlapo NS, Maity A, et al. Degradation of insecticides used for indoor spraying in malaria control and possible solutions. Malar J. 2011;10:307.CrossRefPubMedPubMedCentral
11.
go back to reference Komalamisra N, Srisawat R, Apiwathanasorn C, Samsung Y, Kaisri P. Residual effect of 10% bifenthrin WP on mosquitoes, and community acceptance, in eastern Thailand. Southeastern Asian J Trop Med Public Health. 2009;40:1221–5. Komalamisra N, Srisawat R, Apiwathanasorn C, Samsung Y, Kaisri P. Residual effect of 10% bifenthrin WP on mosquitoes, and community acceptance, in eastern Thailand. Southeastern Asian J Trop Med Public Health. 2009;40:1221–5.
12.
go back to reference Vatandoost H, Abai MR, Abbasi M, Shaeghi M, Abtahi M, Rafie F. Designing of a laboratory model for evaluation of the residual effects of deltamethrin (K-Othrine WP 5%) on different surfaces against malaria vector, Anopheles stephensi (Diptera: Culicidae). J Vector Borne Dis. 2009;46:261–7.PubMed Vatandoost H, Abai MR, Abbasi M, Shaeghi M, Abtahi M, Rafie F. Designing of a laboratory model for evaluation of the residual effects of deltamethrin (K-Othrine WP 5%) on different surfaces against malaria vector, Anopheles stephensi (Diptera: Culicidae). J Vector Borne Dis. 2009;46:261–7.PubMed
13.
go back to reference Etang J, Nwane P, Mbida JA, Piamea M, Manga B, Souop D, et al. Variations of insecticide residual bio-efficacy on different types of walls: results from a community-based trial in south Cameroon. Malar J. 2011;10:333.CrossRefPubMedPubMedCentral Etang J, Nwane P, Mbida JA, Piamea M, Manga B, Souop D, et al. Variations of insecticide residual bio-efficacy on different types of walls: results from a community-based trial in south Cameroon. Malar J. 2011;10:333.CrossRefPubMedPubMedCentral
14.
go back to reference Raghavendra K, Ghosh SK, Eapen A, Tiwari SN, Satyanarayan TS, Ravindran J, et al. Field evaluation of lambda-cyhalothrin (ICON 10 CS) indoor residual spraying against Anopheles culicifacies in India. J Vector Borne Dis. 2011;48:18–26.PubMed Raghavendra K, Ghosh SK, Eapen A, Tiwari SN, Satyanarayan TS, Ravindran J, et al. Field evaluation of lambda-cyhalothrin (ICON 10 CS) indoor residual spraying against Anopheles culicifacies in India. J Vector Borne Dis. 2011;48:18–26.PubMed
15.
go back to reference Mulambalah CS, Siamba DN, Ngeiywa MM, Vulule JM. Evaluation of lambda-cyhalothrin persistence on different indoor surfaces in a malaria-epidemic prone area in Kenya. Res J Biol Sci. 2010;5:258–63.CrossRef Mulambalah CS, Siamba DN, Ngeiywa MM, Vulule JM. Evaluation of lambda-cyhalothrin persistence on different indoor surfaces in a malaria-epidemic prone area in Kenya. Res J Biol Sci. 2010;5:258–63.CrossRef
16.
go back to reference Rohani A, Saadiyah I, Walgun A, Lee HL. Laboratory study on the effect of deltamethrin WG and WP formulations against Anopheles maculatus Theobald (Diptera:Culicidae) on rough and smooth surfaces of bamboo wall. Trop Biomed. 2007;24:77–82.PubMed Rohani A, Saadiyah I, Walgun A, Lee HL. Laboratory study on the effect of deltamethrin WG and WP formulations against Anopheles maculatus Theobald (Diptera:Culicidae) on rough and smooth surfaces of bamboo wall. Trop Biomed. 2007;24:77–82.PubMed
17.
go back to reference Raeisi A, Abai MR, Akbarzadeh K, Nateghpour M, Sartipi M, Hassanzehi A, et al. Residual effects of deltamethrin WG 250% as a new formulation on different surfaces against Anopheles stephensi, in Southeastern Iran. Iranian J Arthropod-Borne Dis. 2010;4:60–5. Raeisi A, Abai MR, Akbarzadeh K, Nateghpour M, Sartipi M, Hassanzehi A, et al. Residual effects of deltamethrin WG 250% as a new formulation on different surfaces against Anopheles stephensi, in Southeastern Iran. Iranian J Arthropod-Borne Dis. 2010;4:60–5.
18.
go back to reference White GB. Anopheles gambiae complex and disease transmission in Africa. Trans R Soc Trop Med Hyg. 1974;68:279–301.CrossRef White GB. Anopheles gambiae complex and disease transmission in Africa. Trans R Soc Trop Med Hyg. 1974;68:279–301.CrossRef
20.
go back to reference Yewhalaw D, Balkew M, Shililu J, Suleman S, Getachew A, Ashenbo G, et al. Determination of the residual efficacy of carbamate and organophosphate insecticides used for indoor residual spraying for malaria control in Ethiopia. Malar J. 2017;16:471.CrossRefPubMedPubMedCentral Yewhalaw D, Balkew M, Shililu J, Suleman S, Getachew A, Ashenbo G, et al. Determination of the residual efficacy of carbamate and organophosphate insecticides used for indoor residual spraying for malaria control in Ethiopia. Malar J. 2017;16:471.CrossRefPubMedPubMedCentral
21.
go back to reference Tukey JW. One degree of freedom for non-additivity. Biometrics. 1949;5:232–42.CrossRef Tukey JW. One degree of freedom for non-additivity. Biometrics. 1949;5:232–42.CrossRef
22.
23.
go back to reference Russell TL, Govella NJ, Azizi S, Drakely CJ, Kachur SP, Killeen GF. Increased proportions of outdoor feeding among residual malaria vector populations following increased use of insecticide-treated nets in rural Tanzania. Malar J. 2011;10:80.CrossRefPubMedPubMedCentral Russell TL, Govella NJ, Azizi S, Drakely CJ, Kachur SP, Killeen GF. Increased proportions of outdoor feeding among residual malaria vector populations following increased use of insecticide-treated nets in rural Tanzania. Malar J. 2011;10:80.CrossRefPubMedPubMedCentral
24.
go back to reference Govella JN, Ferguson H. Why use of interventions targeting outdoor biting mosquitoes will be necessary to achieve malaria elimination. Front Physiol. 2012;199:1–5. Govella JN, Ferguson H. Why use of interventions targeting outdoor biting mosquitoes will be necessary to achieve malaria elimination. Front Physiol. 2012;199:1–5.
Metadata
Title
Evaluation of the long-term efficacy of K-Othrine® PolyZone on three surfaces against laboratory reared Anopheles gambiae in semi-field conditions
Authors
James C. Dunford
Alden S. Estep
Christy M. Waits
Alec G. Richardson
David F. Hoel
Karin Horn
Todd W. Walker
Jessika S. Blersch
Jerry D. Kerce
Robert A. Wirtz
Publication date
01-12-2018
Publisher
BioMed Central
Published in
Malaria Journal / Issue 1/2018
Electronic ISSN: 1475-2875
DOI
https://doi.org/10.1186/s12936-018-2239-z

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