Skip to main content
Top
Published in: Malaria Journal 1/2016

Open Access 01-12-2016 | Review

A review of new challenges and prospects for malaria elimination in Mutare and Mutasa Districts, Zimbabwe

Authors: Shadreck Sande, Moses Zimba, Peter Chinwada, Hieronymo Takundwa Masendu, Joseph Mberikunshe, Aramu Makuwaza

Published in: Malaria Journal | Issue 1/2016

Login to get access

Abstract

This review outlines and discusses the new challenges in malaria control and prospects for its elimination in Mutare and Mutasa Districts, Zimbabwe. The burden of malaria has declined significantly over the past 5 years in most regions in Zimbabwe, including Mutare and Mutasa Districts. The nationwide malaria reduction has been primarily linked to scaled-up vector control interventions and early diagnosis and treatment with effective anti-malarial medicines. The successes recorded have prompted Zimbabwe’s National Malaria Control Programme to commit to a global health agenda of eliminating malaria in all districts in the country. However, despite the decline in malaria burden in Mutare and Mutasa Districts, there is clear evidence of new challenges, including changes in vector behaviour, resistance to insecticides and anti-malarial medicines, invasion of new areas by vectors, vectors in various combination of sympatry, changes in vector proportions, outdoor malaria transmission, climate change and lack of meticulousness of spray operators. These new challenges are likely to retard the shift from malaria control to elimination in Mutare and Mutasa Districts.
Literature
2.
go back to reference WHO. Malaria programme reviews: a manual for reviewing the performance of the malaria control and elimination programmes. Geneva: World Health Organization; 2010. WHO. Malaria programme reviews: a manual for reviewing the performance of the malaria control and elimination programmes. Geneva: World Health Organization; 2010.
4.
go back to reference WHO. Global technical strategy for malaria. Geneva: World Health Organization; 2015. WHO. Global technical strategy for malaria. Geneva: World Health Organization; 2015.
5.
go back to reference Lukwa N, Sande S, Makuwaza A, Chiwade T, Netsa M, Asamoa K, et al. Nationwide assessment of insecticide susceptibility in Anopheles gambiae populations from Zimbabwe. Malar J. 2014;13:408.CrossRefPubMedPubMedCentral Lukwa N, Sande S, Makuwaza A, Chiwade T, Netsa M, Asamoa K, et al. Nationwide assessment of insecticide susceptibility in Anopheles gambiae populations from Zimbabwe. Malar J. 2014;13:408.CrossRefPubMedPubMedCentral
6.
go back to reference Sande S, Zimba M, Chinwada P, Masendu HT, Makuwaza A. Malaria vector species composition and relative abundance in Mutare and Mutasa Districts, Zimbabwe. J Entomol Acarol Res. 2015;47:4955.CrossRef Sande S, Zimba M, Chinwada P, Masendu HT, Makuwaza A. Malaria vector species composition and relative abundance in Mutare and Mutasa Districts, Zimbabwe. J Entomol Acarol Res. 2015;47:4955.CrossRef
7.
go back to reference Mpofu SM. Seasonal vector density and disease incidence pattern in an area of Zimbabwe. Trans R Soc Trop Med Hyg. 1985;79:169–75.CrossRefPubMed Mpofu SM. Seasonal vector density and disease incidence pattern in an area of Zimbabwe. Trans R Soc Trop Med Hyg. 1985;79:169–75.CrossRefPubMed
8.
go back to reference Taylor P, Mutambu SL. A review of the malaria situation in Zimbabwe with special reference to the period 1972–1981. Trans R Soc Trop Med Hyg. 1986;80:12–9.CrossRefPubMed Taylor P, Mutambu SL. A review of the malaria situation in Zimbabwe with special reference to the period 1972–1981. Trans R Soc Trop Med Hyg. 1986;80:12–9.CrossRefPubMed
9.
go back to reference Masendu HT, Hunt RH, Koekemoer LL, Brooke BD, Govere J, Coetzee M. Spatial and temporal distributions and insecticide susceptibility of malaria vectors in Zimbabwe. Afr Entomol. 2005;13:25–34. Masendu HT, Hunt RH, Koekemoer LL, Brooke BD, Govere J, Coetzee M. Spatial and temporal distributions and insecticide susceptibility of malaria vectors in Zimbabwe. Afr Entomol. 2005;13:25–34.
10.
go back to reference Leeson HS. Anopheline mosquitoes in Southern Rhodesia. Mem Lond Sch Hyg Trop Med. 1931;4:55. Leeson HS. Anopheline mosquitoes in Southern Rhodesia. Mem Lond Sch Hyg Trop Med. 1931;4:55.
11.
go back to reference Alves W, Blair DM. Malaria control in Southern Rhodesia. J Trop Med Hyg. 1955;58:273–80.PubMed Alves W, Blair DM. Malaria control in Southern Rhodesia. J Trop Med Hyg. 1955;58:273–80.PubMed
12.
go back to reference Mabaso MLH, Sharp B, Lengeler C. Historical review of malaria control in southern Africa with emphasis on the use of indoor residual house-spraying. Trop Med Int Health. 2004;9:846–56.CrossRefPubMed Mabaso MLH, Sharp B, Lengeler C. Historical review of malaria control in southern Africa with emphasis on the use of indoor residual house-spraying. Trop Med Int Health. 2004;9:846–56.CrossRefPubMed
13.
go back to reference Munhenga G. Characterization of resistance mechanisms in the major malaria vector Anopheles arabiensis from southern Africa. South Africa. PhD thesis, University of Witwatersrand; 2010. Munhenga G. Characterization of resistance mechanisms in the major malaria vector Anopheles arabiensis from southern Africa. South Africa. PhD thesis, University of Witwatersrand; 2010.
14.
go back to reference Masendu HT. The role of Anopheles arabiensis in malaria transmission and control in Gokwe and Binga Districts, Zimbabwe. South Africa. MSc dissertation, University of Natal; 1996. Masendu HT. The role of Anopheles arabiensis in malaria transmission and control in Gokwe and Binga Districts, Zimbabwe. South Africa. MSc dissertation, University of Natal; 1996.
15.
go back to reference Dandalo LC. The abundance and biting behaviour of Anopheles merus (Dönitz) in Gokwe South District, Zimbabwe. Zimbabwe. MSc dissertation, University of Zimbabwe; 2007. Dandalo LC. The abundance and biting behaviour of Anopheles merus (Dönitz) in Gokwe South District, Zimbabwe. Zimbabwe. MSc dissertation, University of Zimbabwe; 2007.
16.
go back to reference Sande S, Zimba M, Chinwada P, Masendu HT, Makuwaza, A. Insights into resting behaviour of malaria vector mosquitoes in Mutare and Mutasa Districts of Manicaland Province, Zimbabwe. J Med Entomol. 2016. (Epub ahead of print). Sande S, Zimba M, Chinwada P, Masendu HT, Makuwaza, A. Insights into resting behaviour of malaria vector mosquitoes in Mutare and Mutasa Districts of Manicaland Province, Zimbabwe. J Med Entomol. 2016. (Epub ahead of print).
17.
go back to reference Sande S, Zimba M, Chinwada P, Masendu HT, Makuwaza A. Biting behaviour of Anopheles funestus populations in Mutare and Mutasa Districts, Manicaland Province, Zimbabwe: implications for the malaria control programme. J Vector Borne Dis. 2016;53:1–7. Sande S, Zimba M, Chinwada P, Masendu HT, Makuwaza A. Biting behaviour of Anopheles funestus populations in Mutare and Mutasa Districts, Manicaland Province, Zimbabwe: implications for the malaria control programme. J Vector Borne Dis. 2016;53:1–7.
18.
19.
go back to reference Alves W, Blair DM. An experiment in the control of malaria and bilharziasis. Trans R Soc Trop Med Hyg. 1953;47:299–308.CrossRefPubMed Alves W, Blair DM. An experiment in the control of malaria and bilharziasis. Trans R Soc Trop Med Hyg. 1953;47:299–308.CrossRefPubMed
22.
go back to reference WHO. Malaria elimination: a field manual for low and moderate endemic countries. Geneva: World Health Organization; 2007. WHO. Malaria elimination: a field manual for low and moderate endemic countries. Geneva: World Health Organization; 2007.
23.
go back to reference Lanzaro GC, Lee Y. Speciation in Anopheles gambiae—the distribution of genetic polymorphism and patterns of reproductive isolation among natural populations. InTech. 2013;. doi:10.5772/56232. Lanzaro GC, Lee Y. Speciation in Anopheles gambiae—the distribution of genetic polymorphism and patterns of reproductive isolation among natural populations. InTech. 2013;. doi:10.​5772/​56232.
24.
go back to reference Evans AM, Leeson HS. The funestus series of Anopheles in Southern Rhodesia with descriptions of a new variety. Ann Trop Med Parasit. 1935;29:33.CrossRef Evans AM, Leeson HS. The funestus series of Anopheles in Southern Rhodesia with descriptions of a new variety. Ann Trop Med Parasit. 1935;29:33.CrossRef
25.
go back to reference Green CA, Hunt RH. Interpretations of variation in ovarian polytene chromosomes of An. funestus Giles, An. parensis Gillies and An. aruni. Genetica. 1980;51:187–95.CrossRef Green CA, Hunt RH. Interpretations of variation in ovarian polytene chromosomes of An. funestus Giles, An. parensis Gillies and An. aruni. Genetica. 1980;51:187–95.CrossRef
26.
go back to reference Choi KS, Christian R, Nardini L, Wood OR, Agubuzo E, Muleba M, et al. Insecticide resistance and role in malaria transmission of Anopheles funestus populations from Zambia and Zimbabwe. Parasit Vectors. 2014;7:464.CrossRefPubMedPubMedCentral Choi KS, Christian R, Nardini L, Wood OR, Agubuzo E, Muleba M, et al. Insecticide resistance and role in malaria transmission of Anopheles funestus populations from Zambia and Zimbabwe. Parasit Vectors. 2014;7:464.CrossRefPubMedPubMedCentral
27.
go back to reference Coetzee M, Craig M, Le Sueur D. Distribution of African malaria mosquitoes belonging to the Anopheles gambiae complex. Parasitol Today. 2000;16:74–7.CrossRefPubMed Coetzee M, Craig M, Le Sueur D. Distribution of African malaria mosquitoes belonging to the Anopheles gambiae complex. Parasitol Today. 2000;16:74–7.CrossRefPubMed
28.
go back to reference Gillies MT, De Meillon B. The Anophelinae of Africa south of the Sahara. Publ S Afr Inst Med Res. 1968;54:127–50. Gillies MT, De Meillon B. The Anophelinae of Africa south of the Sahara. Publ S Afr Inst Med Res. 1968;54:127–50.
29.
go back to reference Bruce-Chwatt LJ. Essential malariology. 2nd ed. London: William Heinemann Medical Books; 1985. Bruce-Chwatt LJ. Essential malariology. 2nd ed. London: William Heinemann Medical Books; 1985.
30.
go back to reference Sande S, Zimba M, Chinwada P, Masendu HT, Mazando S, Makuwaza A. The emergence of insecticide resistance in the major malaria vector Anopheles funestus (Diptera: Culicidae) from sentinel sites in Mutare and Mutasa Districts, Zimbabwe. Malar J. 2015;14:466.CrossRefPubMedPubMedCentral Sande S, Zimba M, Chinwada P, Masendu HT, Mazando S, Makuwaza A. The emergence of insecticide resistance in the major malaria vector Anopheles funestus (Diptera: Culicidae) from sentinel sites in Mutare and Mutasa Districts, Zimbabwe. Malar J. 2015;14:466.CrossRefPubMedPubMedCentral
31.
go back to reference Knapp J, Macdonald M, Malone D, Hamon N, Richardson JH. Disruptive technology for vector control: the innovative vector control consortium and the US military join forces to explore transformative insecticide application technology for mosquito control programmes. Malar J. 2015;14:371.CrossRefPubMedPubMedCentral Knapp J, Macdonald M, Malone D, Hamon N, Richardson JH. Disruptive technology for vector control: the innovative vector control consortium and the US military join forces to explore transformative insecticide application technology for mosquito control programmes. Malar J. 2015;14:371.CrossRefPubMedPubMedCentral
32.
go back to reference Kumar V, Kesari S, Chowdhury R, Kumar S, Sinha G, Hussain S, et al. User friendliness, efficiency and spray quality of stirrup pumps versus hand compression pumps for indoor residual spraying. Indian J Med Res. 2013;138:239–43.PubMedPubMedCentral Kumar V, Kesari S, Chowdhury R, Kumar S, Sinha G, Hussain S, et al. User friendliness, efficiency and spray quality of stirrup pumps versus hand compression pumps for indoor residual spraying. Indian J Med Res. 2013;138:239–43.PubMedPubMedCentral
33.
go back to reference WHO. World Health Organization guidance for countries on combining indoor residual spraying and long lasting insecticidal nets. Geneva: World Health Organization; 2014. WHO. World Health Organization guidance for countries on combining indoor residual spraying and long lasting insecticidal nets. Geneva: World Health Organization; 2014.
34.
go back to reference Dallas ABC, Mutambu SL, Taylor P, Olweny CLM, Saunders D. Chloroquine-resistant Plasmodium falciparum in Zimbabwe. Cent Afr J Med. 1984;30:204–5.PubMed Dallas ABC, Mutambu SL, Taylor P, Olweny CLM, Saunders D. Chloroquine-resistant Plasmodium falciparum in Zimbabwe. Cent Afr J Med. 1984;30:204–5.PubMed
35.
go back to reference Mharakurwa S, Mugochi T. Chloroquine- resistant falciparum malaria in an area of rising endemicity in Zimbabwe. J Trop Med Hyg. 1994;97:39–45.PubMed Mharakurwa S, Mugochi T. Chloroquine- resistant falciparum malaria in an area of rising endemicity in Zimbabwe. J Trop Med Hyg. 1994;97:39–45.PubMed
36.
go back to reference Makanda CD. Chloroquine-resistant Plasmodium falciparum at two farms near Mhangura. Cent Afr J Med. 1987;33:66–70.PubMed Makanda CD. Chloroquine-resistant Plasmodium falciparum at two farms near Mhangura. Cent Afr J Med. 1987;33:66–70.PubMed
37.
go back to reference Simooya OO, Mtetwa S, Neill P, Chandiwana SK, Mharakurwa S. A comparative study of schizonticidal efficacy and safety of artemether vs chloquine phosphate in patients with uncomplicated malaria. Cent Afr J Med. 1992;28:257–65. Simooya OO, Mtetwa S, Neill P, Chandiwana SK, Mharakurwa S. A comparative study of schizonticidal efficacy and safety of artemether vs chloquine phosphate in patients with uncomplicated malaria. Cent Afr J Med. 1992;28:257–65.
38.
go back to reference WHO. Global plan for insecticide resistance management. Geneva: World Health Organization; 2012. WHO. Global plan for insecticide resistance management. Geneva: World Health Organization; 2012.
39.
go back to reference Munhenga G, Masendu HT, Brooke BD, Hunt RH, Koekemoer LK. Pyrethroid resistance in major malaria vector Anopheles arabiensis from Gwave, a malaria-endemic area in Zimbabwe. Malar J. 2008;7:247.CrossRefPubMedPubMedCentral Munhenga G, Masendu HT, Brooke BD, Hunt RH, Koekemoer LK. Pyrethroid resistance in major malaria vector Anopheles arabiensis from Gwave, a malaria-endemic area in Zimbabwe. Malar J. 2008;7:247.CrossRefPubMedPubMedCentral
40.
go back to reference Green CA. Malaria epidemiology and anopheline cytogenetics. In: Pal R, Kitzmiller JB, Kanda T, editors. Cytogenetics and Genetics of Vectors. Amsterdam: Elsevier Biomedical; 1982. p. 21–9. Green CA. Malaria epidemiology and anopheline cytogenetics. In: Pal R, Kitzmiller JB, Kanda T, editors. Cytogenetics and Genetics of Vectors. Amsterdam: Elsevier Biomedical; 1982. p. 21–9.
41.
go back to reference Kanyangarara M, Mamini E, Mharakurwa S, Munyati S, Gwanzura L, Kobayashi T, et al. Reduction in malaria incidence following indoor residual spraying with Actellic 300 CS in a setting with pyrethroid resistance: Mutasa District, Zimbabwe. PLoS One. 2016;11:e0151971.CrossRefPubMedPubMedCentral Kanyangarara M, Mamini E, Mharakurwa S, Munyati S, Gwanzura L, Kobayashi T, et al. Reduction in malaria incidence following indoor residual spraying with Actellic 300 CS in a setting with pyrethroid resistance: Mutasa District, Zimbabwe. PLoS One. 2016;11:e0151971.CrossRefPubMedPubMedCentral
42.
go back to reference Lengeler C. Insecticide-treated bednets and curtains for preventing malaria. Cochrane Database Syst Rev. 2004;2:CD000363.PubMed Lengeler C. Insecticide-treated bednets and curtains for preventing malaria. Cochrane Database Syst Rev. 2004;2:CD000363.PubMed
43.
go back to reference Pluess B, Tanser FC, Lengeler C, Sharp BL. Indoor residual spraying for preventing malaria. Cochrane Database Syst Rev. 2010;4:CD006657.PubMed Pluess B, Tanser FC, Lengeler C, Sharp BL. Indoor residual spraying for preventing malaria. Cochrane Database Syst Rev. 2010;4:CD006657.PubMed
Metadata
Title
A review of new challenges and prospects for malaria elimination in Mutare and Mutasa Districts, Zimbabwe
Authors
Shadreck Sande
Moses Zimba
Peter Chinwada
Hieronymo Takundwa Masendu
Joseph Mberikunshe
Aramu Makuwaza
Publication date
01-12-2016
Publisher
BioMed Central
Published in
Malaria Journal / Issue 1/2016
Electronic ISSN: 1475-2875
DOI
https://doi.org/10.1186/s12936-016-1415-2

Other articles of this Issue 1/2016

Malaria Journal 1/2016 Go to the issue
Live Webinar | 27-06-2024 | 18:00 (CEST)

Keynote webinar | Spotlight on medication adherence

Live: Thursday 27th June 2024, 18:00-19:30 (CEST)

WHO estimates that half of all patients worldwide are non-adherent to their prescribed medication. The consequences of poor adherence can be catastrophic, on both the individual and population level.

Join our expert panel to discover why you need to understand the drivers of non-adherence in your patients, and how you can optimize medication adherence in your clinics to drastically improve patient outcomes.

Prof. Kevin Dolgin
Prof. Florian Limbourg
Prof. Anoop Chauhan
Developed by: Springer Medicine
Obesity Clinical Trial Summary

At a glance: The STEP trials

A round-up of the STEP phase 3 clinical trials evaluating semaglutide for weight loss in people with overweight or obesity.

Developed by: Springer Medicine

Highlights from the ACC 2024 Congress

Year in Review: Pediatric cardiology

Watch Dr. Anne Marie Valente present the last year's highlights in pediatric and congenital heart disease in the official ACC.24 Year in Review session.

Year in Review: Pulmonary vascular disease

The last year's highlights in pulmonary vascular disease are presented by Dr. Jane Leopold in this official video from ACC.24.

Year in Review: Valvular heart disease

Watch Prof. William Zoghbi present the last year's highlights in valvular heart disease from the official ACC.24 Year in Review session.

Year in Review: Heart failure and cardiomyopathies

Watch this official video from ACC.24. Dr. Biykem Bozkurt discusses last year's major advances in heart failure and cardiomyopathies.