Published in:
Open Access
01-12-2023 | Ovarian Cancer | Review
Long noncoding RNAs: glycolysis regulators in gynaecologic cancers
Authors:
Nengyuan Lv, Siyi Shen, Qianying Chen, Jinyi Tong
Published in:
Cancer Cell International
|
Issue 1/2023
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Abstract
The three most common gynaecologic cancers that seriously threaten female lives and health are ovarian cancer, cervical cancer, and endometrial cancer. Glycolysis plays a vital role in gynaecologic cancers. Several long noncoding RNAs (lncRNAs) are known to function as oncogenic molecules. LncRNAs impact downstream target genes by acting as ceRNAs, guides, scaffolds, decoys, or signalling molecules. However, the role of glycolysis-related lncRNAs in regulating gynaecologic cancers remains poorly understood. In this review, we emphasize the functional roles of many lncRNAs that have been found to promote glycolysis in gynaecologic cancers and discuss reasonable strategies for future research.