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Open Access 01-12-2014 | Review

Transmission dynamics and control of Ebola virus disease (EVD): a review

Authors: Gerardo Chowell, Hiroshi Nishiura

Published in: BMC Medicine | Issue 1/2014

Abstract

The complex and unprecedented Ebola epidemic ongoing in West Africa has highlighted the need to review the epidemiological characteristics of Ebola Virus Disease (EVD) as well as our current understanding of the transmission dynamics and the effect of control interventions against Ebola transmission. Here we review key epidemiological data from past Ebola outbreaks and carry out a comparative review of mathematical models of the spread and control of Ebola in the context of past outbreaks and the ongoing epidemic in West Africa. We show that mathematical modeling offers useful insights into the risk of a major epidemic of EVD and the assessment of the impact of basic public health measures on disease spread. We also discuss the critical need to collect detailed epidemiological data in real-time during the course of an ongoing epidemic, carry out further studies to estimate the effectiveness of interventions during past outbreaks and the ongoing epidemic, and develop large-scale modeling studies to study the spread and control of viral hemorrhagic fevers in the context of the highly heterogeneous economic reality of African countries.

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Title: Transmission dynamics and control of Ebola virus disease (EVD): a review
Authors: Gerardo Chowell
Hiroshi Nishiura
Publication date: 01-12-2014
Publisher: BioMed Central
Published in: BMC Medicine / Issue 1/2014
Electronic ISSN: 1741-7015
DOI: https://doi.org/10.1186/s12916-014-0196-0

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Transmission dynamics and control of Ebola virus disease (EVD): a review

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