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Published in: BMC Public Health 1/2023

Open Access 01-12-2023 | Human Immunodeficiency Virus | Research

Insights into barriers and facilitators in PrEP uptake and use among migrant men and transwomen who have sex with men in Belgium

Authors: Ella Van Landeghem, Stef Dielen, Aline Semaan, Anke Rotsaert, Jef Vanhamel, Caroline Masquillier, Edwin Wouters, Kristien Wouters, Bea Vuylsteke, Thijs Reyniers, Christiana Nöstlinger

Published in: BMC Public Health | Issue 1/2023

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Abstract

Background

PrEP uptake is low among non-Belgian men and transwomen who have sex with men, although the HIV epidemic among men who have sex with men in Belgium is diversifying in terms of nationalities and ethnicity. We lack an in-depth understanding of this gap.

Methods

We conducted a qualitative study using a grounded theory approach. The data consists of key informants interviews and in-depth interviews with migrant men or transwomen who have sex with men.

Results

We identified four underlying determinants which shape our participants’ experiences and contextualize the barriers to PrEP use. These include (1) the intersectional identities of being migrant and men and transwomen who have sex with men, (2) migration related stressors, (3) mental health and (4) socio-economic vulnerability. Identified barriers include: the accessibility of services; availability of information, social resources and providers’ attitudes. These barriers influence PrEP acceptance and mediated by individual agency this influences their PrEP uptake.

Conclusion

An interplay of several underlying determinants and barriers impacts on PrEP uptake among migrant men and transwomen who have sex with men, illustrating a social gradient in access to PrEP. We need equitable access to the full spectrum of HIV prevention and care for all priority populations, including undocumented migrants. We recommend social and structural conditions that foster exercising these rights, including adapting PrEP service delivery, mental health and social support.
Footnotes
1
We use the “migrant and ethnic minorities” as a term to describe anyone who was not born in Belgium or Western-Europe. We are aware that this is a very diverse population and can include (non-exhaustive list): asylum-seekers, refugees, documented migrant workers and people with irregular status, as well as people with different lengths of residence/stay in the country.
 
Literature
1.
go back to reference Carillon S, Girard G. Mieux comprendre les défis de la médicalisation de la prévention du VIH en France : la prophylaxie préexposition au prisme des sciences sociales. Glob Health Promot. 2020;27(2):149–53.CrossRefPubMed Carillon S, Girard G. Mieux comprendre les défis de la médicalisation de la prévention du VIH en France : la prophylaxie préexposition au prisme des sciences sociales. Glob Health Promot. 2020;27(2):149–53.CrossRefPubMed
3.
go back to reference Scott HM, Spinelli M, Vittinghoff E, Morehead-Gee A, Hirozawa A, James C, et al. Racial/ethnic and HIV risk category disparities in preexposure prophylaxis discontinuation among patients in publicly funded primary care clinics. AIDS. 2019;33(14):2189–95.CrossRefPubMed Scott HM, Spinelli M, Vittinghoff E, Morehead-Gee A, Hirozawa A, James C, et al. Racial/ethnic and HIV risk category disparities in preexposure prophylaxis discontinuation among patients in publicly funded primary care clinics. AIDS. 2019;33(14):2189–95.CrossRefPubMed
6.
go back to reference Fonner VA, Dalglish SL, Kennedy CE, Baggaley R, O’Reilly KR, Koechlin FM, et al. Effectiveness and safety of oral HIV preexposure prophylaxis for all populations. AIDS. 2016;30(12):1973–83.CrossRefPubMed Fonner VA, Dalglish SL, Kennedy CE, Baggaley R, O’Reilly KR, Koechlin FM, et al. Effectiveness and safety of oral HIV preexposure prophylaxis for all populations. AIDS. 2016;30(12):1973–83.CrossRefPubMed
7.
go back to reference McCormack S, Dunn DT, Desai M, Dolling DI, Gafos M, Gilson R, et al. Pre-exposure prophylaxis to prevent the acquisition of HIV-1 infection (PROUD): effectiveness results from the pilot phase of a pragmatic open-label randomised trial. The Lancet. 2016;387(10013):53–60.CrossRef McCormack S, Dunn DT, Desai M, Dolling DI, Gafos M, Gilson R, et al. Pre-exposure prophylaxis to prevent the acquisition of HIV-1 infection (PROUD): effectiveness results from the pilot phase of a pragmatic open-label randomised trial. The Lancet. 2016;387(10013):53–60.CrossRef
8.
go back to reference Molina JM, Capitant C, Spire B, Pialoux G, Cotte L, Charreau I, et al. On-demand preexposure prophylaxis in men at high risk for HIV-1 infection. N Engl J Med. 2015;373(23):2237–46.CrossRefPubMed Molina JM, Capitant C, Spire B, Pialoux G, Cotte L, Charreau I, et al. On-demand preexposure prophylaxis in men at high risk for HIV-1 infection. N Engl J Med. 2015;373(23):2237–46.CrossRefPubMed
10.
go back to reference Vuylsteke B, Reyniers T, Lucet C, Nöstlinger C, Deblonde J, Libois A, et al. High uptake of pre-exposure prophylaxis (PrEP) during early roll-out in Belgium: results from surveillance reports. Sex Health. 2019;16(1):80–3.CrossRefPubMed Vuylsteke B, Reyniers T, Lucet C, Nöstlinger C, Deblonde J, Libois A, et al. High uptake of pre-exposure prophylaxis (PrEP) during early roll-out in Belgium: results from surveillance reports. Sex Health. 2019;16(1):80–3.CrossRefPubMed
12.
go back to reference Dauvrin M, Detollenaere J, de Laet C, Roberfroid D, Vinck I. Improving access to health care for asylum seekers in Belgium: a national stakeholder consultation. Eur J Public Health. 2021;31(Supplement_3):ckab164-616.CrossRef Dauvrin M, Detollenaere J, de Laet C, Roberfroid D, Vinck I. Improving access to health care for asylum seekers in Belgium: a national stakeholder consultation. Eur J Public Health. 2021;31(Supplement_3):ckab164-616.CrossRef
14.
go back to reference Young I, Flowers P, McDaid LM. Barriers to uptake and use of pre-exposure prophylaxis (PrEP) among communities most affected by HIV in the UK: findings from a qualitative study in Scotland. BMJ Open. 2014;4(11):005717.CrossRef Young I, Flowers P, McDaid LM. Barriers to uptake and use of pre-exposure prophylaxis (PrEP) among communities most affected by HIV in the UK: findings from a qualitative study in Scotland. BMJ Open. 2014;4(11):005717.CrossRef
15.
go back to reference Nakasone SE, Young I, Estcourt CS, Calliste J, Flowers P, Ridgway J, et al. Risk perception, safer sex practices and PrEP enthusiasm: barriers and facilitators to oral HIV pre-exposure prophylaxis in Black African and Black Caribbean women in the UK. Sex Transm Infect. 2020;96(5):349.CrossRefPubMed Nakasone SE, Young I, Estcourt CS, Calliste J, Flowers P, Ridgway J, et al. Risk perception, safer sex practices and PrEP enthusiasm: barriers and facilitators to oral HIV pre-exposure prophylaxis in Black African and Black Caribbean women in the UK. Sex Transm Infect. 2020;96(5):349.CrossRefPubMed
16.
go back to reference Hadj L, Desgrées Du Loû A, Dupont J, Nguyen VK. Acceptabilité et freins chez les populations africaines et caribéennes vivant en Île-de-France d’une nouvelle offre de prévention du VIH: le Truvada® en prophylaxie pré-exposition (PrEP). Une enquête exploratoire’. Bull Epidémiol Hebd. 2017;6:110–4. Hadj L, Desgrées Du Loû A, Dupont J, Nguyen VK. Acceptabilité et freins chez les populations africaines et caribéennes vivant en Île-de-France d’une nouvelle offre de prévention du VIH: le Truvada® en prophylaxie pré-exposition (PrEP). Une enquête exploratoire’. Bull Epidémiol Hebd. 2017;6:110–4.
21.
go back to reference Demart. «On n’arrive pas à les toucher»: la PrEP, les migrant. es africain. es et la production de l’ignorance. Glob Health Promot. 2022;29(3):17579759211062132.CrossRef Demart. «On n’arrive pas à les toucher»: la PrEP, les migrant. es africain. es et la production de l’ignorance. Glob Health Promot. 2022;29(3):17579759211062132.CrossRef
22.
go back to reference Annequin M, Villes V, Delabre RM, Alain T, Morel S, Michels D, et al. Are PrEP services in France reaching all those exposed to HIV who want to take PrEP? MSM respondents who are eligible but not using PrEP (EMIS 2017). AIDS Care. 2020;32(sup2):47–56.CrossRefPubMed Annequin M, Villes V, Delabre RM, Alain T, Morel S, Michels D, et al. Are PrEP services in France reaching all those exposed to HIV who want to take PrEP? MSM respondents who are eligible but not using PrEP (EMIS 2017). AIDS Care. 2020;32(sup2):47–56.CrossRefPubMed
23.
go back to reference Calabrese SK, Krakower DS, Mayer KH. Integrating HIV preexposure prophylaxis (PrEP) into routine preventive health care to avoid exacerbating disparities. Am J Public Health. 2017;107(12):1883–9.CrossRefPubMedPubMedCentral Calabrese SK, Krakower DS, Mayer KH. Integrating HIV preexposure prophylaxis (PrEP) into routine preventive health care to avoid exacerbating disparities. Am J Public Health. 2017;107(12):1883–9.CrossRefPubMedPubMedCentral
24.
go back to reference Glaser BG, Strauss AL. The Discovery of Grounded Theory: Strategies for Qualitative Research. Aldine; 1967. (Observations (Chicago, Ill.)). Glaser BG, Strauss AL. The Discovery of Grounded Theory: Strategies for Qualitative Research. Aldine; 1967. (Observations (Chicago, Ill.)).
25.
go back to reference Chun Tie Y, Birks M, Francis K. Grounded theory research: a design framework for novice researchers. SAGE Open Med. 2019;7:205031211882292.CrossRef Chun Tie Y, Birks M, Francis K. Grounded theory research: a design framework for novice researchers. SAGE Open Med. 2019;7:205031211882292.CrossRef
26.
go back to reference Witzel TC, Nutland W, Bourne A. What are the motivations and barriers to pre-exposure prophylaxis (PrEP) use among black men who have sex with men aged 18–45 in London? Results from a qualitative study. Sex Transm Infect. 2019;95(4):262–6.CrossRefPubMed Witzel TC, Nutland W, Bourne A. What are the motivations and barriers to pre-exposure prophylaxis (PrEP) use among black men who have sex with men aged 18–45 in London? Results from a qualitative study. Sex Transm Infect. 2019;95(4):262–6.CrossRefPubMed
27.
go back to reference Quinn K, Bowleg L, Dickson-Gomez J. “The fear of being Black plus the fear of being gay”: the effects of intersectional stigma on PrEP use among young Black gay, bisexual, and other men who have sex with men. Soc Sci Med. 2019;232:86.CrossRefPubMedPubMedCentral Quinn K, Bowleg L, Dickson-Gomez J. “The fear of being Black plus the fear of being gay”: the effects of intersectional stigma on PrEP use among young Black gay, bisexual, and other men who have sex with men. Soc Sci Med. 2019;232:86.CrossRefPubMedPubMedCentral
28.
go back to reference Ahmadinia H, Eriksson-Backa K, Nikou S. Health-seeking behaviours of immigrants, asylum seekers and refugees in Europe: a systematic review of peer-reviewed articles. J Doc. 2022;78(7):18–41.CrossRef Ahmadinia H, Eriksson-Backa K, Nikou S. Health-seeking behaviours of immigrants, asylum seekers and refugees in Europe: a systematic review of peer-reviewed articles. J Doc. 2022;78(7):18–41.CrossRef
30.
go back to reference Haj-Younes J, Abildsnes E, Kumar B, Diaz E. The road to equitable healthcare: a conceptual model developed from a qualitative study of Syrian refugees in Norway. Soc Sci Med. 2022;1:292. Haj-Younes J, Abildsnes E, Kumar B, Diaz E. The road to equitable healthcare: a conceptual model developed from a qualitative study of Syrian refugees in Norway. Soc Sci Med. 2022;1:292.
31.
go back to reference McBride B, Shannon K, Strathdee SA, Goldenberg SM. Structural determinants of HIV/STI prevalence, HIV/STI/sexual and reproductive health access, and condom use among immigrant sex workers globally. AIDS. 2021;35(9):1461–77.CrossRefPubMed McBride B, Shannon K, Strathdee SA, Goldenberg SM. Structural determinants of HIV/STI prevalence, HIV/STI/sexual and reproductive health access, and condom use among immigrant sex workers globally. AIDS. 2021;35(9):1461–77.CrossRefPubMed
32.
go back to reference di Giuseppe K, Kasoka K, Dunkley Y. Investigating preexposure prophylaxis (PrEP) uptake among black African communities in east London and Hertfordshire: a brief report of a mixed methods study. Int J Sex Health. 2019;31(3):291–6.CrossRef di Giuseppe K, Kasoka K, Dunkley Y. Investigating preexposure prophylaxis (PrEP) uptake among black African communities in east London and Hertfordshire: a brief report of a mixed methods study. Int J Sex Health. 2019;31(3):291–6.CrossRef
33.
go back to reference Jones JT, Smith DK, Thorne SL, Wiener J, Michaels S, Gasparac J. Community members’ pre-exposure prophylaxis awareness, attitudes, and trusted sources for PrEP information and provision, context matters survey, 2015–2016. AIDS Educ Prev. 2020;32(2):102-S6.CrossRefPubMed Jones JT, Smith DK, Thorne SL, Wiener J, Michaels S, Gasparac J. Community members’ pre-exposure prophylaxis awareness, attitudes, and trusted sources for PrEP information and provision, context matters survey, 2015–2016. AIDS Educ Prev. 2020;32(2):102-S6.CrossRefPubMed
34.
go back to reference Fuks N, Smith NG, Peláez S, de Stefano J, Brown TL. Acculturation experiences among lesbian, gay, bisexual, and transgender immigrants in Canada. Couns Psychol. 2018;46(3):296–332.CrossRef Fuks N, Smith NG, Peláez S, de Stefano J, Brown TL. Acculturation experiences among lesbian, gay, bisexual, and transgender immigrants in Canada. Couns Psychol. 2018;46(3):296–332.CrossRef
35.
go back to reference Lewis NM, Wilson K. HIV risk behaviours among immigrant and ethnic minority gay and bisexual men in North America and Europe: a systematic review. Soc Sci Med. 2017;1(179):115–28.CrossRef Lewis NM, Wilson K. HIV risk behaviours among immigrant and ethnic minority gay and bisexual men in North America and Europe: a systematic review. Soc Sci Med. 2017;1(179):115–28.CrossRef
36.
go back to reference Doma H, Tran T, Rioseco P, Fisher J. Understanding the relationship between social support and mental health of humanitarian migrants resettled in Australia. BMC Public Health. 2022;22(1):1739.CrossRefPubMedPubMedCentral Doma H, Tran T, Rioseco P, Fisher J. Understanding the relationship between social support and mental health of humanitarian migrants resettled in Australia. BMC Public Health. 2022;22(1):1739.CrossRefPubMedPubMedCentral
37.
go back to reference Reyniers T, Buffel V, Thunnissen E, Vuylsteke B, Siegel M, Nöstlinger C, et al. Increased anxiety and depression among belgian sexual minority groups during the first COVID-19 lockdown—results from an online survey. Front Public Health. 2022;11:10. Reyniers T, Buffel V, Thunnissen E, Vuylsteke B, Siegel M, Nöstlinger C, et al. Increased anxiety and depression among belgian sexual minority groups during the first COVID-19 lockdown—results from an online survey. Front Public Health. 2022;11:10.
38.
go back to reference Thunnissen E, Buffel V, Reyniers T, Nöstlinger C, Wouters E. From physical distancing to social loneliness among gay men and other men having sex with men in belgium: examining the disruption of the social network and social support structures. Int J Environ Res Public Health. 2022;19(11):6873.CrossRefPubMedPubMedCentral Thunnissen E, Buffel V, Reyniers T, Nöstlinger C, Wouters E. From physical distancing to social loneliness among gay men and other men having sex with men in belgium: examining the disruption of the social network and social support structures. Int J Environ Res Public Health. 2022;19(11):6873.CrossRefPubMedPubMedCentral
39.
go back to reference Gorczynski P, Fasoli F. Loneliness in sexual minority and heterosexual individuals: a comparative meta-analysis. J Gay Lesbian Ment Health. 2022;26:112–29.CrossRef Gorczynski P, Fasoli F. Loneliness in sexual minority and heterosexual individuals: a comparative meta-analysis. J Gay Lesbian Ment Health. 2022;26:112–29.CrossRef
40.
go back to reference de Schrijver L, Fomenko E, Krahé B, Dewaele A, Harb J, Janssen E, et al. An assessment of the proportion of LGB+ persons in the Belgian population, their identication as sexual minority, mental health and experienced minority stress. BMC Public Health. 2022;22(1):1807.CrossRefPubMedPubMedCentral de Schrijver L, Fomenko E, Krahé B, Dewaele A, Harb J, Janssen E, et al. An assessment of the proportion of LGB+ persons in the Belgian population, their identication as sexual minority, mental health and experienced minority stress. BMC Public Health. 2022;22(1):1807.CrossRefPubMedPubMedCentral
41.
go back to reference Yarwood V, Checchi F, Lau K, Zimmerman C. LGBTQI + migrants: a systematic review and conceptual framework of health, safety and wellbeing during migration. Int J Environ Res Public Health. 2022;19(2):869.CrossRefPubMedPubMedCentral Yarwood V, Checchi F, Lau K, Zimmerman C. LGBTQI + migrants: a systematic review and conceptual framework of health, safety and wellbeing during migration. Int J Environ Res Public Health. 2022;19(2):869.CrossRefPubMedPubMedCentral
42.
go back to reference Keygnaert I, Vettenburg N, Roelens K, Temmerman M. Sexual health is dead in my body: participatory assessment of sexual health determinants by refugees, asylum seekers and undocumented migrants in Belgium and the Netherlands. BMC Public Health. 2014;14(1):416.CrossRefPubMedPubMedCentral Keygnaert I, Vettenburg N, Roelens K, Temmerman M. Sexual health is dead in my body: participatory assessment of sexual health determinants by refugees, asylum seekers and undocumented migrants in Belgium and the Netherlands. BMC Public Health. 2014;14(1):416.CrossRefPubMedPubMedCentral
43.
go back to reference Martin F, Sashidharan SP. The mental health of adult irregular migrants to Europe: a systematic review. J Immigr Minor Health. 2022;1–9. Martin F, Sashidharan SP. The mental health of adult irregular migrants to Europe: a systematic review. J Immigr Minor Health. 2022;1–9.
44.
go back to reference Munro L, Travers R, John AS, Klein K, Hunter H, Brennan D, et al. A bed of roses?: exploring the experiences of LGBT newcomer youth who migrate to Toronto. Ethn Inequal Health Soc Care. 2013;6(4):137–50.CrossRef Munro L, Travers R, John AS, Klein K, Hunter H, Brennan D, et al. A bed of roses?: exploring the experiences of LGBT newcomer youth who migrate to Toronto. Ethn Inequal Health Soc Care. 2013;6(4):137–50.CrossRef
45.
go back to reference Golembe J, Leyendecker B, Maalej N, Gundlach A, Busch J. Experiences of minority stress and mental health burdens of newly arrived lgbtq* refugees in germany. Sex Res Soc Policy. 2021;18(4):1049–59.CrossRef Golembe J, Leyendecker B, Maalej N, Gundlach A, Busch J. Experiences of minority stress and mental health burdens of newly arrived lgbtq* refugees in germany. Sex Res Soc Policy. 2021;18(4):1049–59.CrossRef
46.
go back to reference Remien RH, Stirratt MJ, Nguyen N, Robbins RN, Pala AN, Mellins CA. Mental health and HIV/AIDS: the need for an integrated response. AIDS. 2019;33(9):1411–20.CrossRefPubMed Remien RH, Stirratt MJ, Nguyen N, Robbins RN, Pala AN, Mellins CA. Mental health and HIV/AIDS: the need for an integrated response. AIDS. 2019;33(9):1411–20.CrossRefPubMed
47.
go back to reference Pagkas-Bather J, Jaramillo J, Henry J, Grandberry V, Ramirez LF, Cervantes L, et al. What’s PrEP?: peer navigator acceptability among minority MSM in Washington. BMC Public Health. 2020;20(1):248.CrossRefPubMedPubMedCentral Pagkas-Bather J, Jaramillo J, Henry J, Grandberry V, Ramirez LF, Cervantes L, et al. What’s PrEP?: peer navigator acceptability among minority MSM in Washington. BMC Public Health. 2020;20(1):248.CrossRefPubMedPubMedCentral
48.
go back to reference Grenfell P, Rafael S, Calliste J, Nutland W. ‘We go where we know’: Reflections from Mobilizing for PrEP and Sexual Health (MobPrESH) – a peer-led PrEP education programme across England, for and by women and non-binary people. Women’s Health. 2022;1:18. Grenfell P, Rafael S, Calliste J, Nutland W. ‘We go where we know’: Reflections from Mobilizing for PrEP and Sexual Health (MobPrESH) – a peer-led PrEP education programme across England, for and by women and non-binary people. Women’s Health. 2022;1:18.
49.
go back to reference Phanuphak N, Sungsing T, Jantarapakde J, Pengnonyang S, Trachunthong D, Mingkwanrungruang P, et al. Princess PrEP program: the first key population-led model to deliver pre-exposure prophylaxis to key populations by key populations in Thailand. Sex Health. 2018;15(6):542–55.CrossRefPubMed Phanuphak N, Sungsing T, Jantarapakde J, Pengnonyang S, Trachunthong D, Mingkwanrungruang P, et al. Princess PrEP program: the first key population-led model to deliver pre-exposure prophylaxis to key populations by key populations in Thailand. Sex Health. 2018;15(6):542–55.CrossRefPubMed
50.
go back to reference Rivet Amico K, Bekker LG. Global PrEP roll-out: recommendations for programmatic success. The Lancet HIV. 2019;6:e137-40.CrossRefPubMed Rivet Amico K, Bekker LG. Global PrEP roll-out: recommendations for programmatic success. The Lancet HIV. 2019;6:e137-40.CrossRefPubMed
51.
go back to reference Golub SA. PrEP Stigma: implicit and explicit drivers of disparity. Current HIV/AIDS Rep. 2018;15:190–7.CrossRef Golub SA. PrEP Stigma: implicit and explicit drivers of disparity. Current HIV/AIDS Rep. 2018;15:190–7.CrossRef
52.
go back to reference Rousseau E, Julies RF, Madubela N, Kassim S. Novel platforms for biomedical HIV prevention delivery to key populations — community mobile clinics, peer-supported, pharmacy-Led PrEP delivery, and the use of telemedicine. Current HIV/AIDS Rep. 2021;18:500–7.CrossRef Rousseau E, Julies RF, Madubela N, Kassim S. Novel platforms for biomedical HIV prevention delivery to key populations — community mobile clinics, peer-supported, pharmacy-Led PrEP delivery, and the use of telemedicine. Current HIV/AIDS Rep. 2021;18:500–7.CrossRef
53.
go back to reference Murray LR, Brigeiro M, Monteiro S. A retreat from human rights? A reflection on sex work’s place in contemporary HIV prevention. Glob Public Health. 2021;1–15. Murray LR, Brigeiro M, Monteiro S. A retreat from human rights? A reflection on sex work’s place in contemporary HIV prevention. Glob Public Health. 2021;1–15.
54.
go back to reference UNAIDS. Understanding Fast-Track: Accelerating Action to end the AIDS epidemic by 2030. Geneva, Switzerland; 2020. UNAIDS. Understanding Fast-Track: Accelerating Action to end the AIDS epidemic by 2030. Geneva, Switzerland; 2020.
Metadata
Title
Insights into barriers and facilitators in PrEP uptake and use among migrant men and transwomen who have sex with men in Belgium
Authors
Ella Van Landeghem
Stef Dielen
Aline Semaan
Anke Rotsaert
Jef Vanhamel
Caroline Masquillier
Edwin Wouters
Kristien Wouters
Bea Vuylsteke
Thijs Reyniers
Christiana Nöstlinger
Publication date
01-12-2023
Publisher
BioMed Central
Published in
BMC Public Health / Issue 1/2023
Electronic ISSN: 1471-2458
DOI
https://doi.org/10.1186/s12889-023-15540-y

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