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Published in: BMC Public Health 1/2020

01-12-2020 | Hypertension | Research article

Burden of prehypertension among adults in Kenya: a retrospective analysis of findings from the Healthy Heart Africa (HHA) Programme

Authors: Jared O. Mecha, Elizabeth N. Kubo, Collins O. Odhiambo, Freda G. Kinoti, Kennedy Njau, Gerald Yonga, Elijah N. Ogola

Published in: BMC Public Health | Issue 1/2020

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Abstract

Background

Hypertension is the leading risk factor for mortality globally. African countries, including Kenya, have a high and rising prevalence of hypertension. Prehypertension is associated with an increased risk of progression to overt hypertension and a higher risk of cardiovascular disease and mortality. Despite this, little is documented on the prevalence and distribution of prehypertension in sub-Saharan Africa. This study sought to estimate the overall burden of prehypertension in Kenyan adults enrolled in a large hypertension control programme, Healthy Heart Africa. The distribution and determinants of prehypertension in the sample were explored as secondary objectives.

Methods

This was a post hoc analysis of cross-sectional data obtained from population-level blood pressure (BP) screening of adults aged ≥18 years in the community and ambulatory care facilities in 17/47 sub-national administrative units in Kenya. All participants with a complete record for systolic and diastolic BP were included. Descriptive analyses were performed for sociodemographic characteristics. Pearson’s chi-square test was used to assess differences in categorical variables. Multivariate logistic regression analysis was performed to identify factors independently associated with prehypertension.

Results

Of 5,985,185 participant records that were included in the analysis, 34% were men (mean age: 45 [SD 2.9] years). The majority (63%) lived in rural Kenya. The prevalence of prehypertension was 54.5% and that of hypertension was 20.8%. Characteristics that were independently associated with prehypertension (adjusted odds ratio [95% CI]) included male sex (1.23 [±0.0023], p <  0.001 for all age groups > 25 years) and rural residence (1.60 [±0.023], p <  0.001).

Conclusions

Approximately one in every two Kenyan adults has prehypertension. This calls for urgent development and roll-out of a national BP screening and control programme. It also provides a strong basis for the formulation of multisectoral national policies that will ensure implementation of evidence-based, low-cost public health interventions geared towards primary prevention of hypertension, especially in population groups that are traditionally considered at low risk, such as young adults and rural residents.
Literature
1.
go back to reference Zhou M, Wang H, Zeng X, Yin P, Zhu J, Chen W, et al. Mortality, morbidity, and risk factors in China and its provinces, 1990-2017: a systematic analysis for the global burden of disease study 2017. Lancet. 2019;394(10204):1145–58.CrossRef Zhou M, Wang H, Zeng X, Yin P, Zhu J, Chen W, et al. Mortality, morbidity, and risk factors in China and its provinces, 1990-2017: a systematic analysis for the global burden of disease study 2017. Lancet. 2019;394(10204):1145–58.CrossRef
3.
go back to reference Ataklte F, Erqou S, Kaptoge S, Taye B, Echouffo-Tcheugui JB, Kengne AP. Burden of undiagnosed hypertension in sub-Saharan Africa: a systematic review and meta-analysis. Hypertension. 2015;65:291–8.CrossRef Ataklte F, Erqou S, Kaptoge S, Taye B, Echouffo-Tcheugui JB, Kengne AP. Burden of undiagnosed hypertension in sub-Saharan Africa: a systematic review and meta-analysis. Hypertension. 2015;65:291–8.CrossRef
4.
go back to reference Wamai RG, Kengne AP, Levitt N. Non-communicable diseases surveillance: overview of magnitude and determinants in Kenya from STEPwise approach survey of 2015. BMC Public Health. 2018;18(3):1224.CrossRef Wamai RG, Kengne AP, Levitt N. Non-communicable diseases surveillance: overview of magnitude and determinants in Kenya from STEPwise approach survey of 2015. BMC Public Health. 2018;18(3):1224.CrossRef
5.
go back to reference Ogola EN, Barasa F, Barasa AL, Gitura BM, Njuguna B, Beaney T, et al. May Measurement Month 2017: the results of blood pressure screening of 14 845 individuals in Kenya-Sub-Saharan Africa. Eur Heart J Suppl. 2019;21(Suppl D):D71–3.CrossRef Ogola EN, Barasa F, Barasa AL, Gitura BM, Njuguna B, Beaney T, et al. May Measurement Month 2017: the results of blood pressure screening of 14 845 individuals in Kenya-Sub-Saharan Africa. Eur Heart J Suppl. 2019;21(Suppl D):D71–3.CrossRef
6.
go back to reference Chobanian AV, Bakris GL, Black HR, Cushman WC, Green LA, Izzo JL Jr, et al. The seventh report of the joint National Committee on prevention, detection, evaluation, and treatment of high blood pressure: the JNC 7 report. JAMA. 2003;289(19):2560–72.CrossRef Chobanian AV, Bakris GL, Black HR, Cushman WC, Green LA, Izzo JL Jr, et al. The seventh report of the joint National Committee on prevention, detection, evaluation, and treatment of high blood pressure: the JNC 7 report. JAMA. 2003;289(19):2560–72.CrossRef
7.
go back to reference Svetkey LP. Management of prehypertension. Hypertension. 2005;45:1056–61.CrossRef Svetkey LP. Management of prehypertension. Hypertension. 2005;45:1056–61.CrossRef
9.
go back to reference Onyango MJ, Kombe I, Nyamongo DS, Mwangi M. A study to determine the prevalence and factors associated with hypertension among employees working at a call Centre Nairobi Kenya. Pan Afr Med J. 2017;27:178.CrossRef Onyango MJ, Kombe I, Nyamongo DS, Mwangi M. A study to determine the prevalence and factors associated with hypertension among employees working at a call Centre Nairobi Kenya. Pan Afr Med J. 2017;27:178.CrossRef
10.
go back to reference Joshi MD, Ayah R, Njau EK, Wanjiru R, Kayima JK, Njeru EK, et al. Prevalence of hypertension and associated cardiovascular risk factors in an urban slum in Nairobi, Kenya: a population-based survey. BMC Public Health. 2014;14:1177.CrossRef Joshi MD, Ayah R, Njau EK, Wanjiru R, Kayima JK, Njeru EK, et al. Prevalence of hypertension and associated cardiovascular risk factors in an urban slum in Nairobi, Kenya: a population-based survey. BMC Public Health. 2014;14:1177.CrossRef
11.
go back to reference Ogola EN, Okello FO, Herr JL, Macgregor-Skinner E, Mulvaney A, Yonga G. Healthy heart Africa-Kenya: a 12-month prospective evaluation of program impact on health care providers’ knowledge and treatment of hypertension. Glob Heart. 2019;14(1):61–70.CrossRef Ogola EN, Okello FO, Herr JL, Macgregor-Skinner E, Mulvaney A, Yonga G. Healthy heart Africa-Kenya: a 12-month prospective evaluation of program impact on health care providers’ knowledge and treatment of hypertension. Glob Heart. 2019;14(1):61–70.CrossRef
12.
go back to reference Smith L. New AHA recommendations for blood pressure measurement. Am Fam Physician. 2005;72(7):1391–8. Smith L. New AHA recommendations for blood pressure measurement. Am Fam Physician. 2005;72(7):1391–8.
13.
go back to reference Mainous AG III, Everett CJ, Liszka H, King DE, Egan BM. Prehypertension and mortality in a nationally representative cohort. Am J of Cardiol. 2004;94(12):1496–500.CrossRef Mainous AG III, Everett CJ, Liszka H, King DE, Egan BM. Prehypertension and mortality in a nationally representative cohort. Am J of Cardiol. 2004;94(12):1496–500.CrossRef
14.
go back to reference Wang Y, Wang QJ. The prevalence of prehypertension and hypertension among US adults according to the new joint national committee guidelines: new challenges of the old problem. Arch Intern Med. 2004;164(19):2126–34.CrossRef Wang Y, Wang QJ. The prevalence of prehypertension and hypertension among US adults according to the new joint national committee guidelines: new challenges of the old problem. Arch Intern Med. 2004;164(19):2126–34.CrossRef
15.
go back to reference Choi KM, Park HS, Han JH, Lee JS, Lee J, Ryu OH, et al. Prevalence of prehypertension and hypertension in a Korean population: Korean National Health and nutrition survey 2001. J Hypertens. 2006;24(8):1515–21.CrossRef Choi KM, Park HS, Han JH, Lee JS, Lee J, Ryu OH, et al. Prevalence of prehypertension and hypertension in a Korean population: Korean National Health and nutrition survey 2001. J Hypertens. 2006;24(8):1515–21.CrossRef
16.
go back to reference Nuwaha F, Musinguzi G. Pre-hypertension in Uganda: a cross-sectional study. BMC Cardiovasc Disord. 2013;13:101.CrossRef Nuwaha F, Musinguzi G. Pre-hypertension in Uganda: a cross-sectional study. BMC Cardiovasc Disord. 2013;13:101.CrossRef
17.
go back to reference Tsai PS, Ke TL, Huang CJ, Tsai JC, Chen PL, Wang SY, et al. Prevalence and determinants of prehypertension status in the Taiwanese general population. J Hypertens. 2005;23(7):1355–60.CrossRef Tsai PS, Ke TL, Huang CJ, Tsai JC, Chen PL, Wang SY, et al. Prevalence and determinants of prehypertension status in the Taiwanese general population. J Hypertens. 2005;23(7):1355–60.CrossRef
18.
go back to reference Ferguson TS, Tulloch-Reid MK, Younger NO, McFarlane SR, Francis DK, Wilks RJ. Prehypertension in Jamaica: a review of data from recent studies. West Indian Med J. 2011;60(4):429–33.PubMed Ferguson TS, Tulloch-Reid MK, Younger NO, McFarlane SR, Francis DK, Wilks RJ. Prehypertension in Jamaica: a review of data from recent studies. West Indian Med J. 2011;60(4):429–33.PubMed
19.
go back to reference Grotto I, Grossman E, Huerta M, Sharabi Y. Prevalence of prehypertension and associated cardiovascular risk profiles among young Israeli adults. Hypertension. 2006;48(2):254–9.CrossRef Grotto I, Grossman E, Huerta M, Sharabi Y. Prevalence of prehypertension and associated cardiovascular risk profiles among young Israeli adults. Hypertension. 2006;48(2):254–9.CrossRef
20.
go back to reference Sun Z, Zheng L, Wei Y, Li J, Zhang X, Zhang X, et al. Prevalence and risk factors of the rural adult people prehypertension status in Liaoning Province of China. Circ J. 2007;71(4):550–3.CrossRef Sun Z, Zheng L, Wei Y, Li J, Zhang X, Zhang X, et al. Prevalence and risk factors of the rural adult people prehypertension status in Liaoning Province of China. Circ J. 2007;71(4):550–3.CrossRef
21.
go back to reference Agyemang C, Owusu-Dabo E. Prehypertension in the Ashanti region of Ghana, West Africa: an opportunity for early prevention of clinical hypertension. Public Health. 2008;122(1):19–24.CrossRef Agyemang C, Owusu-Dabo E. Prehypertension in the Ashanti region of Ghana, West Africa: an opportunity for early prevention of clinical hypertension. Public Health. 2008;122(1):19–24.CrossRef
22.
go back to reference Lam CS, Cheng S, Choong K, Larson MG, Murabito JM, Newton-Cheh C, et al. Influence of sex and hormone status on circulating natriuretic peptides. J Am Coll of Cardiol. 2011;58(6):618–26.CrossRef Lam CS, Cheng S, Choong K, Larson MG, Murabito JM, Newton-Cheh C, et al. Influence of sex and hormone status on circulating natriuretic peptides. J Am Coll of Cardiol. 2011;58(6):618–26.CrossRef
24.
go back to reference Appel LJ, Moore TJ, Obarzanek E, Vollmer WM, Svetkey LP, Sacks FM, et al. A clinical trial of the effects of dietary patterns on blood pressure. DASH collaborative research group. N Engl J Med. 1997;336(16):1117–24.CrossRef Appel LJ, Moore TJ, Obarzanek E, Vollmer WM, Svetkey LP, Sacks FM, et al. A clinical trial of the effects of dietary patterns on blood pressure. DASH collaborative research group. N Engl J Med. 1997;336(16):1117–24.CrossRef
25.
go back to reference O'Brien E, Parati G, Stergiou G, Asmar R, Beilin L, Bilo G, et al. European Society of Hypertension position paper on ambulatory blood pressure monitoring. J Hypertens. 2013;31(9):1731–68.CrossRef O'Brien E, Parati G, Stergiou G, Asmar R, Beilin L, Bilo G, et al. European Society of Hypertension position paper on ambulatory blood pressure monitoring. J Hypertens. 2013;31(9):1731–68.CrossRef
Metadata
Title
Burden of prehypertension among adults in Kenya: a retrospective analysis of findings from the Healthy Heart Africa (HHA) Programme
Authors
Jared O. Mecha
Elizabeth N. Kubo
Collins O. Odhiambo
Freda G. Kinoti
Kennedy Njau
Gerald Yonga
Elijah N. Ogola
Publication date
01-12-2020
Publisher
BioMed Central
Published in
BMC Public Health / Issue 1/2020
Electronic ISSN: 1471-2458
DOI
https://doi.org/10.1186/s12889-020-8363-z

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