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Published in: BMC Medical Research Methodology 1/2022

Open Access 01-12-2022 | Coronavirus | Research article

Detecting the patient’s need for help with machine learning based on expressions

Author: Lauri Lahti

Published in: BMC Medical Research Methodology | Issue 1/2022

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Abstract

Background

Developing machine learning models to support health analytics requires increased understanding about statistical properties of self-rated expression statements used in health-related communication and decision making. To address this, our current research analyzes self-rated expression statements concerning the coronavirus COVID-19 epidemic and with a new methodology identifies how statistically significant differences between groups of respondents can be linked to machine learning results.

Methods

A quantitative cross-sectional study gathering the “need for help” ratings for twenty health-related expression statements concerning the coronavirus epidemic on an 11-point Likert scale, and nine answers about the person’s health and wellbeing, sex and age. The study involved online respondents between 30 May and 3 August 2020 recruited from Finnish patient and disabled people’s organizations, other health-related organizations and professionals, and educational institutions (n = 673). We propose and experimentally motivate a new methodology of influence analysis concerning machine learning to be applied for evaluating how machine learning results depend on and are influenced by various properties of the data which are identified with traditional statistical methods.

Results

We found statistically significant Kendall rank-correlations and high cosine similarity values between various health-related expression statement pairs concerning the “need for help” ratings and a background question pair. With tests of Wilcoxon rank-sum, Kruskal-Wallis and one-way analysis of variance (ANOVA) between groups we identified statistically significant rating differences for several health-related expression statements in respect to groupings based on the answer values of background questions, such as the ratings of suspecting to have the coronavirus infection and having it depending on the estimated health condition, quality of life and sex. Our new methodology enabled us to identify how statistically significant rating differences were linked to machine learning results thus helping to develop better human-understandable machine learning models.

Conclusions

The self-rated “need for help” concerning health-related expression statements differs statistically significantly depending on the person’s background information, such as his/her estimated health condition, quality of life and sex. With our new methodology statistically significant rating differences can be linked to machine learning results thus enabling to develop better machine learning to identify, interpret and address the patient’s needs for well-personalized care.
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Literature
1.
go back to reference Gallagher JE, Wilkie AA, Cordner A, Hudgens E, Ghio A, Birch R, Wade T. (2016). Factors associated with self-reported health: implications for screening level community-based health and environmental studies. BMC Public Health, 16, 640 (2016). https://doi.org/10.1186/s12889-016-3321-5. Gallagher JE, Wilkie AA, Cordner A, Hudgens E, Ghio A, Birch R, Wade T. (2016). Factors associated with self-reported health: implications for screening level community-based health and environmental studies. BMC Public Health, 16, 640 (2016). https://​doi.​org/​10.​1186/​s12889-016-3321-5.
3.
go back to reference Cullati S, Bochatay N, Rossier C, Guessous I, Burton-Jeangros C, Courvoisier DS. Does the single-item self-rated health measure the same thing across different wordings? Construct validity study. Quality of Life Research: An International Journal of Quality of Life Aspects of Treatment Care Rehabilitation. 2020;29(9):2593–604. https://doi.org/10.1007/s11136-020-02533-2.CrossRef Cullati S, Bochatay N, Rossier C, Guessous I, Burton-Jeangros C, Courvoisier DS. Does the single-item self-rated health measure the same thing across different wordings? Construct validity study. Quality of Life Research: An International Journal of Quality of Life Aspects of Treatment Care Rehabilitation. 2020;29(9):2593–604. https://​doi.​org/​10.​1007/​s11136-020-02533-2.CrossRef
7.
go back to reference Tucker CA, Escorpizo R, Cieza A, Lai JS, Stucki G, Ustun TB, Kostanjsek N, Cella D, Forrest CB. Mapping the content of the Patient-Reported Outcomes Measurement Information System (PROMIS®) using the International Classification of Functioning, Health and Disability. Quality Life Res Int J Quality Life Aspects Treatment Care Rehabil. 2014;23(9):2431–8. https://doi.org/10.1007/s11136-014-0691-y.CrossRef Tucker CA, Escorpizo R, Cieza A, Lai JS, Stucki G, Ustun TB, Kostanjsek N, Cella D, Forrest CB. Mapping the content of the Patient-Reported Outcomes Measurement Information System (PROMIS®) using the International Classification of Functioning, Health and Disability. Quality Life Res Int J Quality Life Aspects Treatment Care Rehabil. 2014;23(9):2431–8. https://​doi.​org/​10.​1007/​s11136-014-0691-y.CrossRef
8.
go back to reference Anttila H, Kokko K, Hiekkala S, Weckström P, Paltamaa J. (2017). Asiakaslähtöinen Toimintakykyni-sovellus. Kehittäminen ja käytettävyystutkimus. Kansaneläkelaitos (Kela), Työpapereita 119, ISSN: 2323-9239. http://hdl.handle.net/10138/187061. Anttila H, Kokko K, Hiekkala S, Weckström P, Paltamaa J. (2017). Asiakaslähtöinen Toimintakykyni-sovellus. Kehittäminen ja käytettävyystutkimus. Kansaneläkelaitos (Kela), Työpapereita 119, ISSN: 2323-9239. http://​hdl.​handle.​net/​10138/​187061.
14.
go back to reference Rojas-Barahona L, Tseng B, Dai Y, Mansfield C, Ramadan O, Ultes S, Crawford M, Gašić M. (2018). Deep learning for language understanding of mental health concepts derived from cognitive behavioural therapy. Proceedings of the Ninth International Workshop on Health Text Mining and Information Analysis, 2018. DOI:https://doi.org/10.18653/v1/w18-5606. Rojas-Barahona L, Tseng B, Dai Y, Mansfield C, Ramadan O, Ultes S, Crawford M, Gašić M. (2018). Deep learning for language understanding of mental health concepts derived from cognitive behavioural therapy. Proceedings of the Ninth International Workshop on Health Text Mining and Information Analysis, 2018. DOI:https://​doi.​org/​10.​18653/​v1/​w18-5606.
15.
go back to reference Shickel B, Siegel S, Heesacker M, Benton S, Rashidi P. Automatic detection and classification of cognitive distortions in mental health text. Research Article . 2019 manuscript published on 23 September 2019 at https://arxiv.org/abs/1909.07502. Shickel B, Siegel S, Heesacker M, Benton S, Rashidi P. Automatic detection and classification of cognitive distortions in mental health text. Research Article . 2019 manuscript published on 23 September 2019 at https://​arxiv.​org/​abs/​1909.​07502.
19.
go back to reference Sinclair S, Jaggi P, Hack TF, Russell L, McClement S, Cuthbertson L, Selman L, Leget C. (2020). Initial validation of a patient-reported measure of compassion: determining the content validity and clinical sensibility among patients living with a life-limiting and incurable illness. The Patient - Patient-Centered Outcomes Research, volume 13, pages 327–337. https://doi.org/10.1007/s40271-020-00409-8. Sinclair S, Jaggi P, Hack TF, Russell L, McClement S, Cuthbertson L, Selman L, Leget C. (2020). Initial validation of a patient-reported measure of compassion: determining the content validity and clinical sensibility among patients living with a life-limiting and incurable illness. The Patient - Patient-Centered Outcomes Research, volume 13, pages 327–337. https://​doi.​org/​10.​1007/​s40271-020-00409-8.
20.
go back to reference Sinclair S, Jaggi P, Hack TF, McClement SE, Cuthbertson LA. A practical guide for item generation in measure development: insights from the development of a patient-reported experience measure of compassion. J Nurs Meas. 2020 28(1), DOI:https://doi.org/10.1891/JNM-D-19-00020. Sinclair S, Jaggi P, Hack TF, McClement SE, Cuthbertson LA. A practical guide for item generation in measure development: insights from the development of a patient-reported experience measure of compassion. J Nurs Meas. 2020 28(1), DOI:https://​doi.​org/​10.​1891/​JNM-D-19-00020.
27.
go back to reference Hughes M, Li I, Kotoulas S, Suzumura T. (2017). Medical text classification using convolutional neural networks. Studies in Health Technology and Informatics, volume 235, pages 246-250. PMID: 28423791. Hughes M, Li I, Kotoulas S, Suzumura T. (2017). Medical text classification using convolutional neural networks. Studies in Health Technology and Informatics, volume 235, pages 246-250. PMID: 28423791.
32.
go back to reference Koskinen S, Lundqvist A, Ristiluoma N, editors (2012). Health, functional capacity and welfare in Finland in 2011. National Institute for Health and Welfare in Finland (THL [as of 2019 the new official English name is: Finnish Institute for Health and Welfare]), Report 68/2012. 290 pages. Helsinki, Finland, 2012. ISBN 978-952-245-768-4 (printed), ISBN 978-952-245-769-1 (online publication, http://urn.fi/URN:ISBN:978-952-245-769-1). A health questionnaire appendix “Terveys 2011, tutkimus suomalaisten terveydestä ja toimintakyvystä, terveyskysely”, form T4095, https://thl.fi/documents/10531/2797097/T4095_terveyskysely.pdf. Koskinen S, Lundqvist A, Ristiluoma N, editors (2012). Health, functional capacity and welfare in Finland in 2011. National Institute for Health and Welfare in Finland (THL [as of 2019 the new official English name is: Finnish Institute for Health and Welfare]), Report 68/2012. 290 pages. Helsinki, Finland, 2012. ISBN 978-952-245-768-4 (printed), ISBN 978-952-245-769-1 (online publication, http://​urn.​fi/​URN:​ISBN:​978-952-245-769-1). A health questionnaire appendix “Terveys 2011, tutkimus suomalaisten terveydestä ja toimintakyvystä, terveyskysely”, form T4095, https://​thl.​fi/​documents/​10531/​2797097/​T4095_​terveyskysely.​pdf.​
33.
go back to reference Lahti L. (2020). Interpretation of the patient’s need for help can be supported with machine learning. In Mansnérus, Juli, Lahti, Raimo, & Blick, Amanda, editors, Personalized medicine: legal and ethical challenges. Faculty of Law, University of Helsinki, Finland, Forum Iuris Series, Helsinki, 2020. ISBN 978-951-51-6940-2 (printed), ISBN 978-951-51-5021-9 (pdf), ISSN 2670-1219. DOI: https://doi.org/10.31885/9789515150219. https://doi.org/10.31885/9789515169419. Lahti L. (2020). Interpretation of the patient’s need for help can be supported with machine learning. In Mansnérus, Juli, Lahti, Raimo, & Blick, Amanda, editors, Personalized medicine: legal and ethical challenges. Faculty of Law, University of Helsinki, Finland, Forum Iuris Series, Helsinki, 2020. ISBN 978-951-51-6940-2 (printed), ISBN 978-951-51-5021-9 (pdf), ISSN 2670-1219. DOI: https://​doi.​org/​10.​31885/​9789515150219. https://​doi.​org/​10.​31885/​9789515169419.​
39.
go back to reference TensorFlow image classification tutorial. (2020). TensorFlow image classification tutorial with Python language scripts. https://www.tensorflow.org/tutorials/images/classification; https://github.com/tensorflow/docs/blob/master/site/en/tutorials/images/classification.ipynb; https://www.tensorflow.org/api_docs/python/tf/keras/layers/Conv2D. TensorFlow image classification tutorial. (2020). TensorFlow image classification tutorial with Python language scripts. https://​www.​tensorflow.​org/​tutorials/​images/​classification; https://github.com/tensorflow/docs/blob/master/site/en/tutorials/images/classification.ipynb; https://www.tensorflow.org/api_docs/python/tf/keras/layers/Conv2D.
41.
go back to reference Finnish Institute for Health and Welfare. (2020). Web pages offering guidelines about coronavirus (COVID-19) disease. When to seek admission for care and guidance concerning the symptoms and care. Published in Finnish. Terveyden ja hyvinvoinnin laitos (THL). https://thl.fi/fi/web/infektiotaudit-ja-rokotukset/taudit-ja-torjunta/taudit-ja-taudinaiheuttajat-a-o/koronavirus-covid-19/koronavirustauti-milloin-on-hakeuduttava-hoitoon; https://thl.fi/fi/web/infektiotaudit-ja-rokotukset/ajankohtaista/ajankohtaista-koronaviruksesta-covid-19/oireet-ja-hoito-koronavirus/koronaviruksen-hoito-ja-ohjeet-sairastuneelle;https://thl.fi/fi/web/infektiotaudit-ja-rokotukset/ajankohtaista/ajankohtaista-koronaviruksesta-covid-19/oireet-ja-hoito-koronavirus. Finnish Institute for Health and Welfare. (2020). Web pages offering guidelines about coronavirus (COVID-19) disease. When to seek admission for care and guidance concerning the symptoms and care. Published in Finnish. Terveyden ja hyvinvoinnin laitos (THL). https://​thl.​fi/​fi/​web/​infektiotaudit-ja-rokotukset/​taudit-ja-torjunta/​taudit-ja-taudinaiheuttaja​t-a-o/​koronavirus-covid-19/​koronavirustauti​-milloin-on-hakeuduttava-hoitoon; https://thl.fi/fi/web/infektiotaudit-ja-rokotukset/ajankohtaista/ajankohtaista-koronaviruksesta-covid-19/oireet-ja-hoito-koronavirus/koronaviruksen-hoito-ja-ohjeet-sairastuneelle;https://thl.fi/fi/web/infektiotaudit-ja-rokotukset/ajankohtaista/ajankohtaista-koronaviruksesta-covid-19/oireet-ja-hoito-koronavirus.
47.
go back to reference Sullivan M, Bishop S, Pivik J. The pain catastrophizing scale: development and validation. Psychological Assessment. 1995;7(4):524–53.CrossRef Sullivan M, Bishop S, Pivik J. The pain catastrophizing scale: development and validation. Psychological Assessment. 1995;7(4):524–53.CrossRef
54.
go back to reference Carroll JS. The effect of imagining an event on expectations for the event: an interpretation in terms of the availability heuristic. J Exp Soc Psychol. 1978;14(1):88–96.CrossRef Carroll JS. The effect of imagining an event on expectations for the event: an interpretation in terms of the availability heuristic. J Exp Soc Psychol. 1978;14(1):88–96.CrossRef
55.
go back to reference Sherman SJ, Cialdini RB, Schwartzman DF, Reynolds KD. Imagining can heighten or lower the perceived likelihood of contracting a disease: the mediating effect of ease of imagery. Pers Soc Psychol Bull. 1985;11(1):118–27.CrossRef Sherman SJ, Cialdini RB, Schwartzman DF, Reynolds KD. Imagining can heighten or lower the perceived likelihood of contracting a disease: the mediating effect of ease of imagery. Pers Soc Psychol Bull. 1985;11(1):118–27.CrossRef
56.
go back to reference Lombrozo T. Simplicity and probability in causal explanation. Cogn Psychol. 2007;55:232–57.CrossRef Lombrozo T. Simplicity and probability in causal explanation. Cogn Psychol. 2007;55:232–57.CrossRef
Metadata
Title
Detecting the patient’s need for help with machine learning based on expressions
Author
Lauri Lahti
Publication date
01-12-2022
Publisher
BioMed Central
Keywords
Coronavirus
Care
Published in
BMC Medical Research Methodology / Issue 1/2022
Electronic ISSN: 1471-2288
DOI
https://doi.org/10.1186/s12874-021-01502-8

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