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Published in: BMC Medical Research Methodology 1/2018

Open Access 01-12-2018 | Research article

Creation of a new clinical framework – why women choose mastectomy versus breast conserving therapy

Authors: Jeffrey Gu, Gary Groot

Published in: BMC Medical Research Methodology | Issue 1/2018

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Abstract

Background

Clinical medicine has lagged behind other fields in understanding and utilizing frameworks to guide research. In this article, we introduce a new framework to examine why women choose mastectomy versus breast conserving therapy in early stage breast cancer, and highlight the importance of utilizing a conceptual framework to guide clinical research.

Methods

The framework we present was developed through integrating previous literature, frameworks, theories, models, and the author’s past research.

Results

We present a conceptual framework that illustrates the central domains that influence women’s choice between mastectomy versus breast conserving therapy. These have been organized into three broad constructs: clinicopathological factors, physician factors, and individual factors with subgroups of sociodemographic, geographic, and individual belief factors. The aim of this framework is to provide a comprehensive basis to describe, examine, and explain the factors that influence women’s choice of mastectomy versus breast conserving therapy at the individual level.

Conclusion

We have developed a framework with the purpose of helping health care workers and policy makers better understand the multitude of factors that influence a patient’s choice of therapy at an individual level. We hope this framework is useful for future scholars to utilize, challenge, and build upon in their own work on decision-making in the setting of breast cancer. For clinician-researchers who have limited experience with frameworks, this paper will highlight the importance of utilizing a conceptual framework to guide future research and provide an example.
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Metadata
Title
Creation of a new clinical framework – why women choose mastectomy versus breast conserving therapy
Authors
Jeffrey Gu
Gary Groot
Publication date
01-12-2018
Publisher
BioMed Central
Published in
BMC Medical Research Methodology / Issue 1/2018
Electronic ISSN: 1471-2288
DOI
https://doi.org/10.1186/s12874-018-0533-7

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