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Published in: BMC Cardiovascular Disorders 1/2015

Open Access 01-12-2015 | Research article

The duration of balloon inflation affects the luminal diameter of coronary segments after bioresorbable vascular scaffolds deployment

Authors: Sabato Sorrentino, Salvatore De Rosa, Giuseppe Ambrosio, Annalisa Mongiardo, Carmen Spaccarotella, Alberto Polimeni, Jolanda Sabatino, Daniele Torella, Gianluca Caiazzo, Ciro Indolfi

Published in: BMC Cardiovascular Disorders | Issue 1/2015

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Abstract

Background

Adequate expansion is critical to achieve optimal Bioresorbable Vascular Scaffolds (BVS) apposition to the vessel wall. However, compared to metallic stents, BVS present different mechanical properties. Hence, slow deployment and maintenance of balloon inflation for at least 30” is recommended for BVS implantation. However, since no evidences are available demonstrating the superiority of a longer balloon dilatation time, the implantation technique is highly variable among different centers.

Methods

A total of 24 BVS-treated lesions were included in the present analysis. After BVS deployment at 12 atmosphere (ATM) the balloon was rapidly deflated and scaffold expansion was documented with an angiogram. The same balloon was then inflated again and kept at 12 ATM for 30”. Finally, a further angiogram was obtained to evaluate BVS expansion. Quantitative coronary angiography (QCA) was performed at each step.

Results

A significant increase of minimal luminal diameter (MLD)-to-reference scaffold diameter (RSD) ratio (MLD to RSD Ration, MR-Ratio) from 0.70 ± 0.10 after initial stent deployment to 0.79 ± 0.10 after the 30”-long balloon dilation was observed (p < 0.001). Of note, this result was consistent across all sub-segments, as well as across almost all lesion subgroups. A substantial reduction in the prevalence of residual stenosis from 29 % to 17 % was registered after the 30”-long dilation.

Conclusions

Our results strongly support the maintenance of balloon inflation for at least 30” during BVS deployment to achieve optimal scaffold expansion and minimize the occurrence of residual stenosis.
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Metadata
Title
The duration of balloon inflation affects the luminal diameter of coronary segments after bioresorbable vascular scaffolds deployment
Authors
Sabato Sorrentino
Salvatore De Rosa
Giuseppe Ambrosio
Annalisa Mongiardo
Carmen Spaccarotella
Alberto Polimeni
Jolanda Sabatino
Daniele Torella
Gianluca Caiazzo
Ciro Indolfi
Publication date
01-12-2015
Publisher
BioMed Central
Published in
BMC Cardiovascular Disorders / Issue 1/2015
Electronic ISSN: 1471-2261
DOI
https://doi.org/10.1186/s12872-015-0163-5

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