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Open Access 01-12-2020 | Aortic Valve Replacement | Correspondence

Problems of subgroup analysis in randomized controlled trial

Author: Hans-Joachim Priebe

Published in: BMC Anesthesiology | Issue 1/2020

Abstract

Multiple subgroup analyses of the same data increase the risk of generating false positive findings. All outcomes and planned subgroup analyses should thus be prespecified and described in the original trial registry. When outcome changes during an ongoing trial seem justifiable, publications must disclose and explain such changes.

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Title: Problems of subgroup analysis in randomized controlled trial
Author: Hans-Joachim Priebe
Publication date: 01-12-2020
Publisher: BioMed Central
Keywords: Aortic Valve Replacement
Transesophageal Echocardiography
Aortic Valve Replacement
Aortic Valve Replacement
Published in: BMC Anesthesiology / Issue 1/2020
Electronic ISSN: 1471-2253
DOI: https://doi.org/10.1186/s12871-020-01105-8

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Problems of subgroup analysis in randomized controlled trial

Abstract

Keynote webinar | Spotlight on medication adherence

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Abstract

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