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Arthritis Research & Therapy
Published in: Arthritis Research & Therapy 1/2001

01-04-2001 | Meeting abstract

Overexpression and induction of heat shock protein (Hsp) 70 protects in vitro and in vivofrom mono-iodoacetate (MIA)-induced chondrocytes death

Authors: C Cournil, B Liagre, L Grossin, C Vol, A Abid, JY Jouzeau, B Terlain, P Netter, P Gillet

Published in: Arthritis Research & Therapy | Special Issue 1/2001

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Excerpt

Cartilage hypocellularity due to cell death contributes to the development of OA. Experimental exposure to MIA results in either chondrocyte necrosis (in vitro) or experimental OA with apoptosis when injected ia (in vivo). As Hsp-70 is known to protect from cell death, we have evaluated the beneficial properties of its over-expression or induction in rat chondrocyte cells (RCC) after MIA exposure. …
Metadata
Title
Overexpression and induction of heat shock protein (Hsp) 70 protects in vitro and in vivofrom mono-iodoacetate (MIA)-induced chondrocytes death
Authors
C Cournil
B Liagre
L Grossin
C Vol
A Abid
JY Jouzeau
B Terlain
P Netter
P Gillet
Publication date
01-04-2001
Publisher
BioMed Central
Published in
Arthritis Research & Therapy / Issue Special Issue 1/2001
Electronic ISSN: 1478-6362
DOI
https://doi.org/10.1186/ar369

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Keynote webinar | Spotlight on medication adherence

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Live: Thursday 27th June 2024, 18:00-19:30 (CEST)

WHO estimates that half of all patients worldwide are non-adherent to their prescribed medication. The consequences of poor adherence can be catastrophic, on both the individual and population level.

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Developed by: Springer Medicine
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Developed by: Springer Medicine

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