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Arthritis Research & Therapy
Published in: Arthritis Research & Therapy 6/2011

01-12-2011 | Review

Type I interferon pathway in adult and juvenile dermatomyositis

Authors: Emily C Baechler, Hatice Bilgic, Ann M Reed

Published in: Arthritis Research & Therapy | Issue 6/2011

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Abstract

Gene expression profiling and protein studies of the type I interferon pathway have revealed important insights into the disease process in adult and juvenile dermatomyositis. The most prominent and consistent feature has been a characteristic whole blood gene signature indicating upregulation of the type I interferon pathway. Upregulation of the type I interferon protein signature has added additional markers of disease activity and insight into the pathogenesis of the disease.
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Metadata
Title
Type I interferon pathway in adult and juvenile dermatomyositis
Authors
Emily C Baechler
Hatice Bilgic
Ann M Reed
Publication date
01-12-2011
Publisher
BioMed Central
Published in
Arthritis Research & Therapy / Issue 6/2011
Electronic ISSN: 1478-6362
DOI
https://doi.org/10.1186/ar3531

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