Published in:
Open Access
01-12-2011 | Review
Understanding urine output in critically ill patients
Authors:
Matthieu Legrand, Didier Payen
Published in:
Annals of Intensive Care
|
Issue 1/2011
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Abstract
Urine output often is used as a marker of acute kidney injury but also to guide fluid resuscitation in critically ill patients. Although decrease of urine output may be associated to a decrease of glomerular filtration rate due to decrease of renal blood flow or renal perfusion pressure, neurohormonal factors and functional changes may influence diuresis and natriuresis in critically ill patients. The purpose of this review is to discuss the mechanisms of diuresis regulation, which may help to interpret the urine output in critically ill patients and the appropriate treatment to be initiated in case of changes in urine output.