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Journal of the International AIDS Society
Published in: Journal of the International AIDS Society 4/2010

Open Access 01-12-2010 | Poster presentation

Clinical application of genotypic co-receptor tropism testing from viral RNA and proviral DNA: week 24 analysis of the Berlin maraviroc cohort

Authors: MJ Obermeier, A Carganico, S Dupke, D Schranz, C Cordes, M Freiwald, G Klausen, S Köppe, C Schuler, C Mayr, D Schleehauf, T Berg, I Krznaric, A Baumgarten

Published in: Journal of the International AIDS Society | Special Issue 4/2010

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Excerpt

Before initiating an antiretroviral combination therapy which includes Maraviroc as one of its components, a coreceptor tropism test has to be performed. As Maraviroc is only effective against HIV strains that are using CCR5 as coreceptor a thoroughly validated and reliable assay should be performed. In case of treatment change due to toxicity, testing should also be possible using proviral DNA. …
Metadata
Title
Clinical application of genotypic co-receptor tropism testing from viral RNA and proviral DNA: week 24 analysis of the Berlin maraviroc cohort
Authors
MJ Obermeier
A Carganico
S Dupke
D Schranz
C Cordes
M Freiwald
G Klausen
S Köppe
C Schuler
C Mayr
D Schleehauf
T Berg
I Krznaric
A Baumgarten
Publication date
01-12-2010
Publisher
BioMed Central
DOI
https://doi.org/10.1186/1758-2652-13-S4-P129

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Keynote webinar | Spotlight on medication adherence

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WHO estimates that half of all patients worldwide are non-adherent to their prescribed medication. The consequences of poor adherence can be catastrophic, on both the individual and population level.

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Developed by: Springer Medicine
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