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Gut Pathogens
Published in: Gut Pathogens 1/2010

Open Access 01-12-2010 | Review

Helicobacter pylori: a poor man's gut pathogen?

Authors: Mohammed Mahdy Khalifa, Radwa Raed Sharaf, Ramy Karam Aziz

Published in: Gut Pathogens | Issue 1/2010

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Abstract

Helicobacter pylori is one of the human pathogens with highest prevalence around the world; yet, its principal mode of transmission remains largely unknown. The role of H. pylori in gastric disease and cancer has not been established until the end of the 20th century. Since then, its epidemiology has been extensively studied, and an accruing body of literature suggests that not all humans are equally at risk of infection by this gut pathogen. Here, we briefly review the different epidemiological aspects of H. pylori infection with emphasis on those factors related to human poverty. The epidemiology of H. pylori infection is characterized by marked differences between developing and developed countries, notably among children. In addition, congruent lines of evidence point out to socioeconomic factors and living standards as main determinants of the age-dependent acquisition rate of H. pylori, and consequently its prevalence. These data are alarming in the light of the changing global climate and birth rate, which are expected to change the demography of our planet, putting more children at risk of H. pylori and its complications for years to come.
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Metadata
Title
Helicobacter pylori: a poor man's gut pathogen?
Authors
Mohammed Mahdy Khalifa
Radwa Raed Sharaf
Ramy Karam Aziz
Publication date
01-12-2010
Publisher
BioMed Central
Published in
Gut Pathogens / Issue 1/2010
Electronic ISSN: 1757-4749
DOI
https://doi.org/10.1186/1757-4749-2-2

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