Top

Published in:

Open Access 01-12-2011 | Case report

Successful radiopeptide targeting of metastatic anaplastic meningioma: Case report

Authors: Amir Sabet, Hojjat Ahmadzadehfar, Ulrich Herrlinger, Winfried Wilinek, Hans-Jürgen Biersack, Samer Ezziddin

Published in: Radiation Oncology | Issue 1/2011

Abstract

A patient with anaplastic meningioma and lung metastases resistant to conventional treatment underwent radiopeptide therapy with 177Lu- DOTA-octreotate in our institute. The treatment resulted in significant improvement in patient's quality of life and inhibition of tumor progression. This case may eventually help to establish the value of radiopeptide therapy in patients with this rare condition.

Available only for authorised users

Alvarez F, Roda JM, Perez Romero M, Morales C, Sarmiento MA, Blazquez MG: Malignant and atypical meningiomas: a reappraisal of clinical, histological, and computed tomographic features. Neurosurgery 1987,20(5):688-694. 10.1227/00006123-198705000-00003CrossRefPubMed

Figueroa BE, Quint DJ, McKeever PE, Chandler WF: Extracranial metastatic meningioma. Br J Radiol 1999,72(857):513-516.CrossRefPubMed

Karasick JL, Mullan SF: A survey of metastatic meningiomas. J Neurosurg 1974,40(2):206-212. 10.3171/jns.1974.40.2.0206CrossRefPubMed

Kodama K, Doi O, Higashiyama M, Horai T, Tateishi R, Nakagawa H: Primary and metastatic pulmonary meningioma. Cancer 1991,67(5):1412-1417. 10.1002/1097-0142(19910301)67:5<1412::AID-CNCR2820670523>3.0.CO;2-VCrossRefPubMed

van Essen M, Krenning EP, Kooij PP, et al.: Effects of therapy with [177Lu-DOTA0, Tyr3]octreotate in patients with paraganglioma, meningioma, small cell lung carcinoma, and melanoma. J Nucl Med 2006,47(10):1599-1606.PubMed

Bartolomei M, Bodei L, De Cicco C, et al.: Peptide receptor radionuclide therapy with (90)Y-DOTATOC in recurrent meningioma. Eur J Nucl Med Mol Imaging 2009,36(9):1407-1416. 10.1007/s00259-009-1115-zCrossRefPubMed

Costelloe CM, Chuang HH, Madewell JE, Ueno NT: Cancer Response Criteria and Bone Metastases: RECIST 1.1, MDA and PERCIST. J Cancer 2010, 1: 80-92.PubMedCentralCrossRefPubMed

Marosi C, Hassler M, Roessler K, et al.: Meningioma. Crit Rev Oncol Hematol 2008,67(2):153-171. 10.1016/j.critrevonc.2008.01.010CrossRefPubMed

Takahashi JA, Ueba T, Hashimoto N, Nakashima Y, Katsuki N: The combination of mitotic and Ki-67 indices as a useful method for predicting short-term recurrence of meningiomas. Surg Neurol 2004,61(2):149-155. discussion 155-146 10.1016/S0090-3019(03)00575-5CrossRefPubMed

10.

Commins DL, Atkinson RD, Burnett ME: Review of meningioma histopathology. Neurosurg Focus 2007,23(4):E3. 10.3171/FOC-07/10/E3CrossRefPubMed

11.

Delbeke D, Meyerowitz C, Lapidus RL, et al.: Optimal cutoff levels of F-18 fluorodeoxyglucose uptake in the differentiation of low-grade from high-grade brain tumors with PET. Radiology 1995,195(1):47-52.CrossRefPubMed

12.

Hustinx R, Pourdehnad M, Kaschten B, Alavi A: PET imaging for differentiating recurrent brain tumor from radiation necrosis. Radiol Clin North Am 2005,43(1):35-47. 10.1016/j.rcl.2004.09.009CrossRefPubMed

13.

Sisson JC, Shulkin BL: Nuclear medicine imaging of pheochromocytoma and neuroblastoma. Q J Nucl Med 1999,43(3):217-223.PubMed

14.

Schmidt M, Scheidhauer K, Luyken C, et al.: Somatostatin receptor imaging in intracranial tumours. Eur J Nucl Med 1998,25(7):675-686. 10.1007/s002590050269CrossRefPubMed

15.

Nathoo N, Ugokwe K, Chang AS, et al.: The role of 111indium-octreotide brain scintigraphy in the diagnosis of cranial, dural-based meningiomas. J Neurooncol 2007,81(2):167-174.CrossRefPubMed

Title: Successful radiopeptide targeting of metastatic anaplastic meningioma: Case report
Authors: Amir Sabet
Hojjat Ahmadzadehfar
Ulrich Herrlinger
Winfried Wilinek
Hans-Jürgen Biersack
Samer Ezziddin
Publication date: 01-12-2011
Publisher: BioMed Central
Published in: Radiation Oncology / Issue 1/2011
Electronic ISSN: 1748-717X
DOI: https://doi.org/10.1186/1748-717X-6-94

Keynote webinar | Spotlight on medication adherence

Springer Medicine

Successful radiopeptide targeting of metastatic anaplastic meningioma: Case report

Abstract

Keynote webinar | Spotlight on medication adherence

Springer Medicine

Abstract

Please log in to get access to this content

Other articles of this Issue 1/2011

Parotid gland-recovery after radiotherapy in the head and neck region - 36 months follow-up of a prospective clinical study

Outcome of thyroid associated ophthalmopathy treated by radiation therapy

Radiotherapy and "new" drugs-new side effects?

Resveratrol enhances prostate cancer cell response to ionizing radiation. Modulation of the AMPK, Akt and mTOR pathways

Intraoperative radiation therapy for advanced cervical metastasis: a single institution experience

Ionizing radiation and inhibition of angiogenesis in a spontaneous mammary carcinoma and in a syngenic heterotopic allograft tumor model: a comparative study