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Radiation Oncology

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Open Access 01-12-2010 | Research

Planning target volume margins for prostate radiotherapy using daily electronic portal imaging and implanted fiducial markers

Authors: David Skarsgard, Pat Cadman, Ali El-Gayed, Robert Pearcey, Patricia Tai, Nadeem Pervez, Jackson Wu

Published in: Radiation Oncology | Issue 1/2010

Abstract

Background

Fiducial markers and daily electronic portal imaging (EPI) can reduce the risk of geographic miss in prostate cancer radiotherapy. The purpose of this study was to estimate CTV to PTV margin requirements, without and with the use of this image guidance strategy.

Methods

46 patients underwent placement of 3 radio-opaque fiducial markers prior to prostate RT. Daily pre-treatment EPIs were taken, and isocenter placement errors were corrected if they were ≥ 3 mm along the left-right or superior-inferior axes, and/or ≥ 2 mm along the anterior-posterior axis. During-treatment EPIs were then obtained to estimate intra-fraction motion.

Results

Without image guidance, margins of 0.57 cm, 0.79 cm and 0.77 cm, along the left-right, superior-inferior and anterior-posterior axes respectively, are required to give 95% probability of complete CTV coverage each day. With the above image guidance strategy, these margins can be reduced to 0.36 cm, 0.37 cm and 0.37 cm respectively. Correction of all isocenter placement errors, regardless of size, would permit minimal additional reduction in margins.

Conclusions

Image guidance, using implanted fiducial markers and daily EPI, permits the use of narrower PTV margins without compromising coverage of the target, in the radiotherapy of prostate cancer.

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Title: Planning target volume margins for prostate radiotherapy using daily electronic portal imaging and implanted fiducial markers
Authors: David Skarsgard
Pat Cadman
Ali El-Gayed
Robert Pearcey
Patricia Tai
Nadeem Pervez
Jackson Wu
Publication date: 01-12-2010
Publisher: BioMed Central
Published in: Radiation Oncology / Issue 1/2010
Electronic ISSN: 1748-717X
DOI: https://doi.org/10.1186/1748-717X-5-52

Keynote webinar | Spotlight on medication adherence

Springer Medicine

Planning target volume margins for prostate radiotherapy using daily electronic portal imaging and implanted fiducial markers

Abstract

Background

Methods

Results

Conclusions

Keynote webinar | Spotlight on medication adherence

Springer Medicine

Abstract

Background

Methods

Results

Conclusions

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