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Published in: Diagnostic Pathology 1/2011

Open Access 01-12-2011 | Hypothesis

To be at the right place at the right time

Authors: Klaus Kayser, Stephan Borkenfeld, Torsten Goldmann, Gian Kayser

Published in: Diagnostic Pathology | Issue 1/2011

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Abstract

Aim

To analyze the hypothesis of events or neighborhood interactions that is based upon recognizable structures of systems which possess a surface in a four dimensional space - time constellation {x, y, z, t}. To include the theory of hierarchic order of structures and aspects of thermodynamically open systems, especially entropy, structural entropy and entropy flow.

Hypothesis

Any structure is a space - time constellation that occupies a unique space in its environment. The environment can be a system too, and is assumed to be (nearly) constant. Structures can interact in their environment and create a new structure at a higher order level. Interacting structures that create a surface are called a system. Starting from the bottom, such a system is characterized by its inner structures, its surface function, and its neighborhood. Interaction with a neighboring system is called an event. An event can alter a system, create new systems or induce the decay of a system, dependent upon the surrounding lower level system (background).

Results

The hypothesis results in a uniform theory about matter, life, diseases, or behavior. Concrete applications permit the estimation of duration of life in man, for example the effect of solid cancer in man, or appearance of protozoans in sexual or asexual reduplication. In addition, it can successfully describe the development of the universe (small exceed of matter above antimatter at the big bang), or the increase of structures (and systems) with increasing time (development of intelligent systems). The three dimensional space possesses the lowest number of mandatory dimensions to implement such a system.
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Literature
1.
go back to reference Einstein A, Albert Einstein: The human Side - New Glimpses from his Archives. 1979, Princeton, New Yersey: Princeton University Press Einstein A, Albert Einstein: The human Side - New Glimpses from his Archives. 1979, Princeton, New Yersey: Princeton University Press
2.
go back to reference Heisenberg W: Wandlungen in den Grundlagen der Naturwissenschaft. 1959, Stuttgart: S. Hirzel Verlag Heisenberg W: Wandlungen in den Grundlagen der Naturwissenschaft. 1959, Stuttgart: S. Hirzel Verlag
3.
go back to reference Kayser K, Stauch G: Zeitgedanken und Spiegeldenken. 2000, Baden - Baden: Rendevous Verlag Kayser K, Stauch G: Zeitgedanken und Spiegeldenken. 2000, Baden - Baden: Rendevous Verlag
4.
go back to reference Kayser K, Kayser G, Metze K: The concept of structural entropy in tissue-based diagnosis. Anal Quant Cytol Histol. 2007, 29 (5): 296-308.PubMed Kayser K, Kayser G, Metze K: The concept of structural entropy in tissue-based diagnosis. Anal Quant Cytol Histol. 2007, 29 (5): 296-308.PubMed
5.
go back to reference Trintscher KS: Biologie und Information - Eine Diskussion über Probleme der biologischen Thermodynamik. 1967, Leipzig: B. G. Teubner Verlagsgesellschaft Trintscher KS: Biologie und Information - Eine Diskussion über Probleme der biologischen Thermodynamik. 1967, Leipzig: B. G. Teubner Verlagsgesellschaft
6.
go back to reference De Groot SR: Thermodynamik irreversibler Prozesse. 1960, Mannheim: Bibliographisches Institut, 18/18A: De Groot SR: Thermodynamik irreversibler Prozesse. 1960, Mannheim: Bibliographisches Institut, 18/18A:
7.
go back to reference De Groot SR, Mazur P: Non-equilibrium Thermodynamics. 1962, Amsterdam: North-Holland Publishing Company De Groot SR, Mazur P: Non-equilibrium Thermodynamics. 1962, Amsterdam: North-Holland Publishing Company
8.
9.
go back to reference Einstein A: The Meaning of Relativity. 1956, Princeton, New Yersey: Princeton University Press Einstein A: The Meaning of Relativity. 1956, Princeton, New Yersey: Princeton University Press
10.
go back to reference Voronoi G: Nouvelles applications des parametres continus a la theorie des formes quadratiques, deuxieme memoire: recherches sur les paralleloedres primitifs. J Reine Angew Math. 1902, 134: 188-287. Voronoi G: Nouvelles applications des parametres continus a la theorie des formes quadratiques, deuxieme memoire: recherches sur les paralleloedres primitifs. J Reine Angew Math. 1902, 134: 188-287.
11.
go back to reference O'Callaghan JF: An alternative definition for neighborhood of a point. IEEE Trans Comput. 1875, 24: 1121-1125. O'Callaghan JF: An alternative definition for neighborhood of a point. IEEE Trans Comput. 1875, 24: 1121-1125.
12.
go back to reference Zahn CT: Graph-theoretical methods for detecting and describing Gestalt clusters. IEEE Trans Comput. 1971, C-20: 68-86.CrossRef Zahn CT: Graph-theoretical methods for detecting and describing Gestalt clusters. IEEE Trans Comput. 1971, C-20: 68-86.CrossRef
14.
go back to reference Kayser K, et al.: Neighborhood analysis of low magnification structures (glands) in healthy, adenomatous, and carcinomatous colon mucosa. Pathol Res Pract. 1986, 181 (2): 153-8.CrossRefPubMed Kayser K, et al.: Neighborhood analysis of low magnification structures (glands) in healthy, adenomatous, and carcinomatous colon mucosa. Pathol Res Pract. 1986, 181 (2): 153-8.CrossRefPubMed
15.
go back to reference Ruelle D: Zufall und Chaos. 1993, Berlin, Heidelberg, New York: Springer Ruelle D: Zufall und Chaos. 1993, Berlin, Heidelberg, New York: Springer
16.
go back to reference Cheng TP: Relativity, Gravitation and Cosmology: a Basic Introduction. 2005, Oxford, New York: Oxford University Press Cheng TP: Relativity, Gravitation and Cosmology: a Basic Introduction. 2005, Oxford, New York: Oxford University Press
17.
go back to reference Kayser K: Application of structural pattern recognition in histopathology. Syntactic and structural pattern recognition. Edited by: T.P. G. Ferraté, A. Sanfeliu, H. Bunke. 1988, Springer: Berlin Heidelberg New York, 115-135.CrossRef Kayser K: Application of structural pattern recognition in histopathology. Syntactic and structural pattern recognition. Edited by: T.P. G. Ferraté, A. Sanfeliu, H. Bunke. 1988, Springer: Berlin Heidelberg New York, 115-135.CrossRef
18.
go back to reference Kayser K, et al.: TNM stage, immunohistology, syntactic structure analysis and survival in patients with small cell anaplastic carcinoma of the lung. J Cancer Res Clin Oncol. 1987, 113 (5): 473-l80. 10.1007/BF00390042.CrossRefPubMed Kayser K, et al.: TNM stage, immunohistology, syntactic structure analysis and survival in patients with small cell anaplastic carcinoma of the lung. J Cancer Res Clin Oncol. 1987, 113 (5): 473-l80. 10.1007/BF00390042.CrossRefPubMed
19.
go back to reference Kayser K, Hoeffgen H: Pattern recognition in histopathology by orders of textures. Med Inform (Lond). 1984, 9 (1): 55-9.CrossRef Kayser K, Hoeffgen H: Pattern recognition in histopathology by orders of textures. Med Inform (Lond). 1984, 9 (1): 55-9.CrossRef
20.
go back to reference Kayser K, et al.: Combined morphometrical and syntactic structure analysis as tools for histomorphological insight into human lung carcinoma growth. Anal Cell Pathol. 1990, 2 (3): 167-78.PubMed Kayser K, et al.: Combined morphometrical and syntactic structure analysis as tools for histomorphological insight into human lung carcinoma growth. Anal Cell Pathol. 1990, 2 (3): 167-78.PubMed
21.
go back to reference Kayser K, et al.: Primary colorectal carcinomas and their intrapulmonary metastases: clinical, glyco-, immuno- and lectin histochemical, nuclear and syntactic structure analysis with emphasis on correlation with period of occurrence of metastases and survival. Apmis. 2002, 110 (6): 435-46. 10.1034/j.1600-0463.2002.100601.x.CrossRefPubMed Kayser K, et al.: Primary colorectal carcinomas and their intrapulmonary metastases: clinical, glyco-, immuno- and lectin histochemical, nuclear and syntactic structure analysis with emphasis on correlation with period of occurrence of metastases and survival. Apmis. 2002, 110 (6): 435-46. 10.1034/j.1600-0463.2002.100601.x.CrossRefPubMed
22.
go back to reference Gell-Mann M, Tsallis C, eds: Nonextensive Entropy: Interdisciplinary Applications. 2004, Oxford University Press: Oxford Gell-Mann M, Tsallis C, eds: Nonextensive Entropy: Interdisciplinary Applications. 2004, Oxford University Press: Oxford
23.
go back to reference Tsallis C: Introduction to Nonextensive Statistical Mechanics. 2010, Berlin: Springer Tsallis C: Introduction to Nonextensive Statistical Mechanics. 2010, Berlin: Springer
24.
go back to reference Kayser K, Gabius HJ: The application of thermodynamic principles to histochemical and morphometric tissue research: principles and practical outline with focus on the glycosciences. Cell Tissue Res. 1999, 296 (3): 443-55. 10.1007/s004410051305.CrossRefPubMed Kayser K, Gabius HJ: The application of thermodynamic principles to histochemical and morphometric tissue research: principles and practical outline with focus on the glycosciences. Cell Tissue Res. 1999, 296 (3): 443-55. 10.1007/s004410051305.CrossRefPubMed
25.
go back to reference Kayser K, Molnar B, Weinstein RS: Virtual microscopy - Fundamentals, Applications, Perspectives of electronic tissue - based diagnosis. 2007, Berlin: VSV Interdisciplinary Medical Publishing Kayser K, Molnar B, Weinstein RS: Virtual microscopy - Fundamentals, Applications, Perspectives of electronic tissue - based diagnosis. 2007, Berlin: VSV Interdisciplinary Medical Publishing
26.
go back to reference Prigogine I: Introduction to Thermodynamics of Irreversible Processes. 1961, New Yorck: John Wiley & Sons Inc, 2 Prigogine I: Introduction to Thermodynamics of Irreversible Processes. 1961, New Yorck: John Wiley & Sons Inc, 2
27.
go back to reference Eigen M: Selforganization of matter and the evolution of biological macromolecules. Naturwissenschaften. 1971, 58: 465-523. 10.1007/BF00623322.CrossRefPubMed Eigen M: Selforganization of matter and the evolution of biological macromolecules. Naturwissenschaften. 1971, 58: 465-523. 10.1007/BF00623322.CrossRefPubMed
28.
go back to reference Kayser K, Gabius HJ: Graph Theory and the Entropy Concept in Histochemistry. Progress in Histochemistry and Cytochemistry. Edited by: W. Graumann. 1997, Stuttgart, Jena, Lübeck, Ulm: Gustav Fischer, 32: Kayser K, Gabius HJ: Graph Theory and the Entropy Concept in Histochemistry. Progress in Histochemistry and Cytochemistry. Edited by: W. Graumann. 1997, Stuttgart, Jena, Lübeck, Ulm: Gustav Fischer, 32:
29.
go back to reference Kayser K, et al.: Towards an automated virtual slide screening: theoretical considerations and practical experiences of automated tissue-based virtual diagnosis to be implemented in the Internet. Diagn Pathol. 2006, 1: 10-10.1186/1746-1596-1-10.PubMedCentralCrossRefPubMed Kayser K, et al.: Towards an automated virtual slide screening: theoretical considerations and practical experiences of automated tissue-based virtual diagnosis to be implemented in the Internet. Diagn Pathol. 2006, 1: 10-10.1186/1746-1596-1-10.PubMedCentralCrossRefPubMed
30.
go back to reference Guth A: Eternal inflation and its implications. J Phys. 2007, A40: 6811-6826. Guth A: Eternal inflation and its implications. J Phys. 2007, A40: 6811-6826.
Metadata
Title
To be at the right place at the right time
Authors
Klaus Kayser
Stephan Borkenfeld
Torsten Goldmann
Gian Kayser
Publication date
01-12-2011
Publisher
BioMed Central
Published in
Diagnostic Pathology / Issue 1/2011
Electronic ISSN: 1746-1596
DOI
https://doi.org/10.1186/1746-1596-6-68

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