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Open Access 01-12-2011 | Commentary

How much do you know about benign, preneoplastic, non-invasive and invasive neoplastic lesions of the urinary bladder classified according to the 2004 WHO scheme?

Authors: Rodolfo Montironi, Liang Cheng, Marina Scarpelli, Roberta Mazzucchelli, Antonio Lopez-Beltran

Published in: Diagnostic Pathology | Issue 1/2011

Abstract

The aim of this essay is the self assessment of the level of knowledge of the 2004 WHO classification of bladder neoplasms through a series of MCQs, each associated a short commentary. This paper is directed to all who are involved with the application of this classification at the anticancer research, diagnostic, prognostic and therapeutic levels, in particular to uropathologists, urologists and oncologists.

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Epstein JI, Amin MB, Reuter VR, Mostofi FK: The World Health Organization/International Society of Urological Pathology consensus classification of urothelial (transitional cell) neoplasms of the urinary bladder. Bladder Consensus Conference Committee. Am J Surg Pathol. 1998, 22: 1435-1448. 10.1097/00000478-199812000-00001.CrossRefPubMed

Sauter G, Algaba F, Amin MB, Busch C, et al.: Tumours of the urinary system. World Health Organization Classification of Tumours Pathology and Genetics: Tumours of the Urinary System and Male Genital Organs. Edited by: Epstein JI, Eble JN, Sesterhenn I, Sauter G. 2004, Lyon, IARC Press, 89-157.

Jost SP, Gosling JA, Dixon JS: The morphology of normal human bladder urothelium. J Anat. 1989, 167: 103-115.PubMedCentralPubMed

McKenney JK, Desai S, Cohen C, Amin MB: Discriminatory immunohistochemical staining of urothelial carcinoma in situ and non neoplastic urothelium. An analysis of cytokeratin 20, p53, and CD44 antigens. Am J Surg Pathol. 2001, 25: 1074-1078. 10.1097/00000478-200108000-00013.CrossRefPubMed

Montironi R, Lopez-Beltran A: The 2004 WHO classification of bladder tumors: a summary and commentary. Int J Surg Pathol. 2005, 13: 143-153. 10.1177/106689690501300203.CrossRefPubMed

Montironi R, Mazzucchelli R, Scarpelli M, Lopez-Beltran A, Cheng L: Morphological diagnosis of urothelial neoplasms. J Clin Pathol. 2008, 61: 3-10. 10.1136/jcp.2007.049312.CrossRefPubMed

Hodges KB, Lopez-Beltran A, Davidson DD, Montironi R, Cheng L: Urothelial dysplasia and other flat lesions of the urinary bladder: clinicopathologic and molecular features. Hum Pathol. 2010, 41: 155-62. 10.1016/j.humpath.2009.07.002.CrossRefPubMed

Montironi R, Lopez-Beltran A, Scarpelli M, Mazzucchelli R, Cheng L: Morphological classification and definition of benign, preneoplastic and non-invasive neoplastic lesions of the urinary bladder. Histopathology. 2008, 53: 621-33. 10.1111/j.1365-2559.2008.03025.x.CrossRefPubMed

MacLennan GT, Kirkali Z, Cheng L: Histologic grading of noninvasive papillary urothelial neoplasms. Eur Urol. 2007, 51: 889-897. 10.1016/j.eururo.2006.10.037.CrossRefPubMed

10.

Samaratunga H, Makarov DV, Epstein JI: Comparison of WHO/ISUP and WHO classification of noninvasive papillary urothelial neoplasms for risk of progression. Urology. 2002, 60: 315-319. 10.1016/S0090-4295(02)01705-3.CrossRefPubMed

11.

Cheng CW, Chan LW, Chan CK, Ng CF, Cheung HY, Chan SY, Wong WS, To KF: Is surveillance necessary for inverted papilloma in the urinary bladder and urethra?. ANZ J Surg. 2005, 75: 213-7. 10.1111/j.1445-2197.2005.03327.x.CrossRefPubMed

12.

Sung MT, Eble JN, Wang M, Tan PH, Lopez-Beltran A, Cheng L: Inverted papilloma of the urinary bladder: a molecular genetic appraisal. Mod Pathol. 2006, 19: 1289-94. 10.1038/modpathol.3800667.CrossRefPubMed

13.

Hodges KB, Lopez-Beltran A, Maclennan GT, Montironi R, Cheng L: Urothelial lesions with inverted growth patterns: histogenesis, molecular genetic findings, differential diagnosis and clinical management. BJU Int. 2011, 107: 532-537. 10.1111/j.1464-410X.2010.09853.x.CrossRefPubMed

14.

Cheng L, Montironi R, Davidson DD, Lopez-Beltran A: Staging and reporting of urothelial carcinoma of the urinary bladder. Mod Pathol. 2009, 22 (Suppl 2): S70-S95. 10.1038/modpathol.2009.1.CrossRefPubMed

15.

Epstein JI, Amin MB, Reuter VE: Conventional morphologic, prognostic, andpredictive factors and reporting of bladder cancer. Urinary Bladder Biopsy Interpretation. Edited by: Epstein JI. 2010, Philadelphia, Lippincott Williams & Wilkins

16.

Jimenez RE, Keane TE, Hardy HT, Amin MB: pT1 urothelial carcinoma of the bladder: criteria for diagnosis, pitfalls, and clinical implications. Adv Anat Pathol. 2000, 7: 13-25. 10.1097/00125480-200007010-00004.CrossRefPubMed

17.

Philip AT, Amin MB, Tamboli P, Lee TJ, Hill CE, Ro JY: Intravesical adipose tissue: a quantitative study of its presence and location with implications for therapy and prognosis. Am J Surg Pathos. 2000, 24: 1286-1290. 10.1097/00000478-200009000-00013.CrossRef

Title: How much do you know about benign, preneoplastic, non-invasive and invasive neoplastic lesions of the urinary bladder classified according to the 2004 WHO scheme?
Authors: Rodolfo Montironi
Liang Cheng
Marina Scarpelli
Roberta Mazzucchelli
Antonio Lopez-Beltran
Publication date: 01-12-2011
Publisher: BioMed Central
Published in: Diagnostic Pathology / Issue 1/2011
Electronic ISSN: 1746-1596
DOI: https://doi.org/10.1186/1746-1596-6-31

At a glance: The STEP trials

Springer Medicine

How much do you know about benign, preneoplastic, non-invasive and invasive neoplastic lesions of the urinary bladder classified according to the 2004 WHO scheme?

Abstract

At a glance: The STEP trials

Springer Medicine

Abstract

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