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Open Access 01-12-2015 | Oral presentation

Dose transition pathways: a design, analysis and operational tool for dose-finding trials using model-based designs

Authors: Christina Yap, Lucinda Billingham, Charles Craddock, John O'Quigley

Published in: Trials | Special Issue 2/2015

Excerpt

Despite the mounting evidence for the superior performance of model-based dose-finding designs in identifying the maximum tolerated dose compared to traditional up-and-down designs, its use is still very limited in medical literature as there remain several challenges in implementation. …

Title: Dose transition pathways: a design, analysis and operational tool for dose-finding trials using model-based designs
Authors: Christina Yap
Lucinda Billingham
Charles Craddock
John O'Quigley
Publication date: 01-12-2015
Publisher: BioMed Central
Published in: Trials / Issue Special Issue 2/2015
Electronic ISSN: 1745-6215
DOI: https://doi.org/10.1186/1745-6215-16-S2-O13

2024 ASCO Annual Meeting

Springer Medicine

Dose transition pathways: a design, analysis and operational tool for dose-finding trials using model-based designs

Excerpt

2024 ASCO Annual Meeting

Springer Medicine

Excerpt

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