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Tobacco Induced Diseases
Published in: Tobacco Induced Diseases 1/2014

Open Access 01-06-2014 | Meeting abstract

Maternal tobacco use during pregnancy and risk of congenital heart defects in offspring: a systematic review

Authors: Aspasia Tzani, Konstantinos P Economopoulos

Published in: Tobacco Induced Diseases | Special Issue 1/2014

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Excerpt

Numerous human studies have investigated potential teratogenic effects of maternal smoking during pregnancy, with conflicting findings [1, 2]. One of the most common birth malformations is congenital heart defect (CHD) with a prevalence of around 1% of live births [3, 4]. More specifically, several studies indicate that maternal tobacco use is related with increased risk of CHD, whereas other studies do not find any association [5, 6]. The aim of this study is to systematically review the literature regarding the correlation between maternal smoking during pregnancy and the prevalence of CHDs in offspring. …
Literature
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Kallen K: Maternal smoking and congenital heart defects. Eur J Epidemiol. 1999, 15: 731-737. 10.1023/A:1007671631188.CrossRefPubMed
2.
Karatza AA, Giannakopoulos I, Dassios TG, Belavgenis G, Mantagos SP, Varvarigou AA: Periconceptional tobacco smoking and isolated congenital heart defects in the neonatal period. Int J Cardiol. 2011, 148: 295-299. 10.1016/j.ijcard.2009.11.008.CrossRefPubMed
3.
Yerushalmy J: Congenital heart disease and maternal smoking habits. Nature. 1973, 242: 262-263. 10.1038/242262a0.CrossRefPubMed
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Hackshaw A, Rodeck C, Boniface S: Maternal smoking in pregnancy and birth defects: a systematic review based on 173,687 malformed cases and 11.7 million controls. Hum Reprod Update. 2011, 17: 589-604. 10.1093/humupd/dmr022.PubMedCentralCrossRefPubMed
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Perspectives in pediatric cardiology. Epidemiology of congenital heart disease. The Baltimore-Washington Infant Study 1981–1989. Edited by: Ferencz C, Rubin JD, Loffredo CA, Magee CA. New York: Futura Pub, Mount Kisco, 4: 1993-last page.
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Kuciene R, Dulskiene V: Maternal socioeconomic and lifestyle factors during pregnancy and the risk of congenital heart defects. Medicina Kaunas. 2009, 45: 904-909.PubMed
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Malik S, Cleves MA, Honein MA, Romitti PA, Botto LD, Yang S, Hobbs CA: National Birth Defects Prevention Study: Maternal smoking and congenital heart defects. Pediatrics. 2008, 121: e810-e816. 10.1542/peds.2007-1519.CrossRefPubMed
Metadata
Title
Maternal tobacco use during pregnancy and risk of congenital heart defects in offspring: a systematic review
Authors
Aspasia Tzani
Konstantinos P Economopoulos
Publication date
01-06-2014
Publisher
BioMed Central
Published in
Tobacco Induced Diseases / Issue Special Issue 1/2014
Electronic ISSN: 1617-9625
DOI
https://doi.org/10.1186/1617-9625-12-S1-A20

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