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World Journal of Surgical Oncology

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Open Access 01-12-2008 | Case report

A case of virilization induced by a Krukenberg tumor from gastric cancer

Authors: Matthias Hornung, Peter Vogel, Thomas Schubert, Hans-Jürgen Schlitt, Ulrich Bolder

Published in: World Journal of Surgical Oncology | Issue 1/2008

Abstract

Background

The Krukenberg tumor represents ovarian metastases associated with gastric cancer or other gastrointestinal malignancies. Histology shows typical mucus-production and numerous signet-ring cells. Occasionally Krukenberg tumors have endocrine function and, as a consequence, some patients demonstrate hirsutism and virilization.

Case presentation

Here we report a case of virilization associated with an extensive gastric adenocarcinoma and Krukenberg tumor in a premenopausal woman. Virilization occurred three months after diagnosis of gastric cancer and the ovarian tumors. Palliative chemotherapy was initiated as primary therapy, but gastric outlet obstruction required a gastrojejunostomy. In addition, oopherectomy was performed to relieve abdominal tension and to abate hormonal effects. It is likely that virilization of the patient could have been prevented by earlier oopherectomy prior to development of hormone production.

Conclusion

Despite the limitation in survival time early oopherectomy should be considered to prevent the development of virilization even in palliative situations if a Krukenberg tumor is diagnosed with gastric cancer.

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Title: A case of virilization induced by a Krukenberg tumor from gastric cancer
Authors: Matthias Hornung
Peter Vogel
Thomas Schubert
Hans-Jürgen Schlitt
Ulrich Bolder
Publication date: 01-12-2008
Publisher: BioMed Central
Published in: World Journal of Surgical Oncology / Issue 1/2008
Electronic ISSN: 1477-7819
DOI: https://doi.org/10.1186/1477-7819-6-19

Keynote webinar | Spotlight on medication adherence

Springer Medicine

A case of virilization induced by a Krukenberg tumor from gastric cancer

Abstract

Background

Case presentation

Conclusion

Keynote webinar | Spotlight on medication adherence

Springer Medicine

Abstract

Background

Case presentation

Conclusion

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