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World Journal of Surgical Oncology

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Open Access 01-12-2005 | Review

Invasive breast cancer following bilateral subcutaneous mastectomy in a BRCA2 mutation carrier: a case report and review of the literature

Authors: Lidia Kasprzak, Benoit Mesurolle, Francine Tremblay, Maria Galvez, Fawaz Halwani, William D Foulkes

Published in: World Journal of Surgical Oncology | Issue 1/2005

Abstract

Background

Primary prevention of breast cancer through prophylactic mastectomy can reduce the risk of malignancy in high-risk individuals. No type of mastectomy completely removes all breast tissue, but a subcutaneous mastectomy leaves more tissue in situ than does a simple mastectomy.

Case presentation

We report a case of invasive breast cancer in a BRCA2-positive woman 33 years after bilateral subcutaneous mastectomy. To our knowledge, only one case of primary breast cancer after prophylactic mastectomy in a BRCA1-positive patient has been reported in the literature and none in BRCA2-positive individuals.

Conclusion

Careful documentation and long follow-up is essential to fully assess the benefits and risks of preventive surgical procedures in BRCA1 and BRCA2 mutation carriers.

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Title: Invasive breast cancer following bilateral subcutaneous mastectomy in a BRCA2 mutation carrier: a case report and review of the literature
Authors: Lidia Kasprzak
Benoit Mesurolle
Francine Tremblay
Maria Galvez
Fawaz Halwani
William D Foulkes
Publication date: 01-12-2005
Publisher: BioMed Central
Published in: World Journal of Surgical Oncology / Issue 1/2005
Electronic ISSN: 1477-7819
DOI: https://doi.org/10.1186/1477-7819-3-52

Keynote webinar | Spotlight on medication adherence

Springer Medicine

Invasive breast cancer following bilateral subcutaneous mastectomy in a BRCA2 mutation carrier: a case report and review of the literature

Abstract

Background

Case presentation

Conclusion

Keynote webinar | Spotlight on medication adherence

Springer Medicine

Abstract

Background

Case presentation

Conclusion

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