Skip to main content
Top
Published in: BMC Public Health 1/2013

Open Access 01-12-2013 | Research article

Long-term follow-up of a high- and a low-intensity smoking cessation intervention in a dental setting– a randomized trial

Authors: Eva Nohlert, John Öhrvik, Åke Tegelberg, Per Tillgren, Ásgeir R Helgason

Published in: BMC Public Health | Issue 1/2013

Login to get access

Abstract

Background

Achieving lifelong tobacco abstinence is an important public health goal. Most studies use 1-year follow-ups, but little is known about how good these are as proxies for long-term and life-long abstinence. Also, intervention intensity is an important issue for development of efficient and cost-effective cessation treatment protocols.
The study aims were to assess the long-term effectiveness of a high- and a low-intensity treatment (HIT and LIT) for smoking cessation and to analyze to what extent 12-month abstinence predicted long-term abstinence.

Methods

300 smokers attending dental or general health care were randomly assigned to HIT or LIT at the public dental clinic. Main outcome measures were self-reported point prevalence, continuous abstinence (≥6 months), and sustained abstinence. The study was a follow-up after 5–8 years of a previously performed 12-month follow-up, both by postal questionnaires.

Results

Response rate was 85% (n=241) of those still alive and living in Sweden. Abstinence rates were 8% higher in both programs at the long-term than at the 12-month follow-up. The difference of 7% between HIT and LIT had not change, being 31% vs. 24% for point prevalence and 26% vs. 19% for 6-month continuous abstinence, respectively. Significantly more participants in HIT (12%) than in LIT (5%) had been sustained abstinent (p=0.03). Logistic regression analyses showed that abstinence at 12-month follow-up was a strong predictor for abstinence at long-term follow-up.

Conclusions

Abstinence at 12-month follow-up is a good predictor for long-term abstinence. The difference in outcome between HIT and LIT for smoking cessation remains at least 5–8 years after the intervention.

Trial registration number

Appendix
Available only for authorised users
Literature
1.
go back to reference WHO: WHO report on the global tobacco epidemic, 2011. 2011, Geneva: World Health Organization (WHO) WHO: WHO report on the global tobacco epidemic, 2011. 2011, Geneva: World Health Organization (WHO)
2.
go back to reference Doll R, Peto R, Boreham J, Sutherland I: Mortality in relation to smoking: 50 years' observations on male British doctors. BMJ. 2004, 328 (7455): 1519-10.1136/bmj.38142.554479.AE.CrossRefPubMedPubMedCentral Doll R, Peto R, Boreham J, Sutherland I: Mortality in relation to smoking: 50 years' observations on male British doctors. BMJ. 2004, 328 (7455): 1519-10.1136/bmj.38142.554479.AE.CrossRefPubMedPubMedCentral
3.
go back to reference Anthonisen NR, Skeans MA, Wise RA, Manfreda J, Kanner RE, Connett JE: The effects of a smoking cessation intervention on 14.5-year mortality: a randomized clinical trial. Ann Intern Med. 2005, 142 (4): 233-239. 10.7326/0003-4819-142-4-200502150-00005.CrossRefPubMed Anthonisen NR, Skeans MA, Wise RA, Manfreda J, Kanner RE, Connett JE: The effects of a smoking cessation intervention on 14.5-year mortality: a randomized clinical trial. Ann Intern Med. 2005, 142 (4): 233-239. 10.7326/0003-4819-142-4-200502150-00005.CrossRefPubMed
4.
go back to reference Pirie K, Peto R, Reeves GK, Green J, Beral V: The 21st century hazards of smoking and benefits of stopping: a prospective study of one million women in the UK. 2012, UK: Lancet Pirie K, Peto R, Reeves GK, Green J, Beral V: The 21st century hazards of smoking and benefits of stopping: a prospective study of one million women in the UK. 2012, UK: Lancet
5.
go back to reference Surgeon General: The Health Benefits of Smoking Cessation In A Report of the Surgeon General. 1990, Rockville, MD: U.S. Department of Health and Human Services Surgeon General: The Health Benefits of Smoking Cessation In A Report of the Surgeon General. 1990, Rockville, MD: U.S. Department of Health and Human Services
6.
go back to reference Fiore MC, Jaén CR, Baker TB, Bailey WC, Benowitz NL, Curry SJ, Faith Dorfman S, Froelicher ES, Goldstein MG, Healton CG, et al: Treating Tobacco Use and Dependence: 2008 Update. Clinical Practice Guideline. 2008, Rockville, MD, U.S: Department of Health and Human Service. Public Health Service Fiore MC, Jaén CR, Baker TB, Bailey WC, Benowitz NL, Curry SJ, Faith Dorfman S, Froelicher ES, Goldstein MG, Healton CG, et al: Treating Tobacco Use and Dependence: 2008 Update. Clinical Practice Guideline. 2008, Rockville, MD, U.S: Department of Health and Human Service. Public Health Service
7.
go back to reference Carr AB, Ebbert J: Interventions for tobacco cessation in the dental setting. Cochrane Database Syst Rev. 2012, 6: CD005084 Carr AB, Ebbert J: Interventions for tobacco cessation in the dental setting. Cochrane Database Syst Rev. 2012, 6: CD005084
8.
go back to reference Kahende JW, Loomis BR, Adhikari B, Marshall L: A review of economic evaluations of tobacco control programs. Int J Environ Res Public Health. 2009, 6 (1): 51-68.CrossRefPubMed Kahende JW, Loomis BR, Adhikari B, Marshall L: A review of economic evaluations of tobacco control programs. Int J Environ Res Public Health. 2009, 6 (1): 51-68.CrossRefPubMed
9.
go back to reference Nohlert E, Helgason AR, Tillgren P, Tegelberg A, Johansson P: Comparison of the cost-effectiveness of a high- and a low-intensity smoking cessation intervention in Sweden: a randomized trial. Nicotine Tob Res. 2013, Epub 2013/02/14 Nohlert E, Helgason AR, Tillgren P, Tegelberg A, Johansson P: Comparison of the cost-effectiveness of a high- and a low-intensity smoking cessation intervention in Sweden: a randomized trial. Nicotine Tob Res. 2013, Epub 2013/02/14
10.
go back to reference Parrott S, Godfrey C, Raw M, West R, McNeill A: Guidance for commissioners on the cost effectiveness of smoking cessation interventions. Health Educational Authority. Thorax. 1998, 53: 1-38. 10.1136/thx.53.1.1. Suppl 5 Pt 2CrossRef Parrott S, Godfrey C, Raw M, West R, McNeill A: Guidance for commissioners on the cost effectiveness of smoking cessation interventions. Health Educational Authority. Thorax. 1998, 53: 1-38. 10.1136/thx.53.1.1. Suppl 5 Pt 2CrossRef
11.
go back to reference Stead LF, Perera R, Bullen C, Mant D, Lancaster T: Nicotine replacement therapy for smoking cessation. Cochrane Database Syst Rev. 2008, 1: CD000146 Stead LF, Perera R, Bullen C, Mant D, Lancaster T: Nicotine replacement therapy for smoking cessation. Cochrane Database Syst Rev. 2008, 1: CD000146
12.
go back to reference Alpert HR, Connolly GN, Biener L: A prospective cohort study challenging the effectiveness of population-based medical intervention for smoking cessation. Tob Control. 2013, 22 (1): 32-37. 10.1136/tobaccocontrol-2011-050129.CrossRefPubMed Alpert HR, Connolly GN, Biener L: A prospective cohort study challenging the effectiveness of population-based medical intervention for smoking cessation. Tob Control. 2013, 22 (1): 32-37. 10.1136/tobaccocontrol-2011-050129.CrossRefPubMed
13.
go back to reference Etter JF, Laszlo E: Postintervention effect of nicotine replacement therapy for smoking reduction: a randomized trial with a 5-year follow-up. J Clin Psychopharmacol. 2007, 27 (2): 151-155. 10.1097/JCP.0b013e318033bd72.CrossRefPubMed Etter JF, Laszlo E: Postintervention effect of nicotine replacement therapy for smoking reduction: a randomized trial with a 5-year follow-up. J Clin Psychopharmacol. 2007, 27 (2): 151-155. 10.1097/JCP.0b013e318033bd72.CrossRefPubMed
14.
go back to reference Helgason AR, Tomson T, Lund KE, Galanti R, Ahnve S, Gilljam H: Factors related to abstinence in a telephone helpline for smoking cessation. Eur J Public Health. 2004, 14 (3): 306-310. 10.1093/eurpub/14.3.306.CrossRefPubMed Helgason AR, Tomson T, Lund KE, Galanti R, Ahnve S, Gilljam H: Factors related to abstinence in a telephone helpline for smoking cessation. Eur J Public Health. 2004, 14 (3): 306-310. 10.1093/eurpub/14.3.306.CrossRefPubMed
15.
go back to reference West R, Zhou X: Is nicotine replacement therapy for smoking cessation effective in the "real world"? Findings from a prospective multinational cohort study. Thorax. 2007, 62 (11): 998-1002. 10.1136/thx.2007.078758.CrossRefPubMedPubMedCentral West R, Zhou X: Is nicotine replacement therapy for smoking cessation effective in the "real world"? Findings from a prospective multinational cohort study. Thorax. 2007, 62 (11): 998-1002. 10.1136/thx.2007.078758.CrossRefPubMedPubMedCentral
16.
go back to reference Hyland A, Qiang L, Joseph B, Gary G, Steger C, Cummings M: Predictors of cessation in a cohort of current and former smokers followed over 13 years. Nicotine Tob Res. 2004, 6 (Supplement 3): 363-369.CrossRef Hyland A, Qiang L, Joseph B, Gary G, Steger C, Cummings M: Predictors of cessation in a cohort of current and former smokers followed over 13 years. Nicotine Tob Res. 2004, 6 (Supplement 3): 363-369.CrossRef
17.
go back to reference Vangeli E, et al: Predictors of attempts to stop smoking and their success in adult general population samples: a systematic review. Addiction. 2011, 106 (12): 2110-2121. 10.1111/j.1360-0443.2011.03565.x.CrossRefPubMed Vangeli E, et al: Predictors of attempts to stop smoking and their success in adult general population samples: a systematic review. Addiction. 2011, 106 (12): 2110-2121. 10.1111/j.1360-0443.2011.03565.x.CrossRefPubMed
18.
go back to reference Hughes JR, Keely J, Naud S: Shape of the relapse curve and long-term abstinence among untreated smokers. Addiction. 2004, 99 (1): 29-38. 10.1111/j.1360-0443.2004.00540.x.CrossRefPubMed Hughes JR, Keely J, Naud S: Shape of the relapse curve and long-term abstinence among untreated smokers. Addiction. 2004, 99 (1): 29-38. 10.1111/j.1360-0443.2004.00540.x.CrossRefPubMed
19.
go back to reference Hughes JR, Peters EN, Naud S: Relapse to smoking after 1 year of abstinence: a meta-analysis. Addict Behav. 2008, 33 (12): 1516-1520. 10.1016/j.addbeh.2008.05.012.CrossRefPubMedPubMedCentral Hughes JR, Peters EN, Naud S: Relapse to smoking after 1 year of abstinence: a meta-analysis. Addict Behav. 2008, 33 (12): 1516-1520. 10.1016/j.addbeh.2008.05.012.CrossRefPubMedPubMedCentral
20.
go back to reference Wetter DW, Cofta-Gunn L, Fouladi RT, Cinciripini PM, Sui D, Gritz ER: Late relapse/sustained abstinence among former smokers: a longitudinal study. Prev Med. 2004, 39 (6): 1156-1163. 10.1016/j.ypmed.2004.04.028.CrossRefPubMed Wetter DW, Cofta-Gunn L, Fouladi RT, Cinciripini PM, Sui D, Gritz ER: Late relapse/sustained abstinence among former smokers: a longitudinal study. Prev Med. 2004, 39 (6): 1156-1163. 10.1016/j.ypmed.2004.04.028.CrossRefPubMed
21.
go back to reference Etter JF, Stapleton JA: Nicotine replacement therapy for long-term smoking cessation: a meta-analysis. Tob Control. 2006, 15 (4): 280-285. 10.1136/tc.2005.015487.CrossRefPubMedPubMedCentral Etter JF, Stapleton JA: Nicotine replacement therapy for long-term smoking cessation: a meta-analysis. Tob Control. 2006, 15 (4): 280-285. 10.1136/tc.2005.015487.CrossRefPubMedPubMedCentral
22.
go back to reference Lancaster T, Stead LF: Individual behavioural counselling for smoking cessation. Cochrane Database Syst Rev. 2005, 2: CD001292 Lancaster T, Stead LF: Individual behavioural counselling for smoking cessation. Cochrane Database Syst Rev. 2005, 2: CD001292
23.
go back to reference Stead LF, Bergson G, Lancaster T: Physician advice for smoking cessation. Cochrane Database Syst Rev. 2008, 2: CD000165 Stead LF, Bergson G, Lancaster T: Physician advice for smoking cessation. Cochrane Database Syst Rev. 2008, 2: CD000165
24.
go back to reference Stead LF, Perera R, Lancaster T: Telephone counselling for smoking cessation. Cochrane Database Syst Rev. 2006, 3: CD002850 Stead LF, Perera R, Lancaster T: Telephone counselling for smoking cessation. Cochrane Database Syst Rev. 2006, 3: CD002850
25.
go back to reference FHI: Nationella folkhälsoenkäten [Swedish National Public Health Survey]. 2011, Östersund: Statens folkhälsoinstitut, FHI [Swedish National Institute of Public Health] FHI: Nationella folkhälsoenkäten [Swedish National Public Health Survey]. 2011, Östersund: Statens folkhälsoinstitut, FHI [Swedish National Institute of Public Health]
26.
go back to reference FHI: Tobak och avvänjning [Tobacco and weaning]. 2009, Östersund: Statens folkhälsoinstitut (FHI) [Swedish National Institute of Public Health] FHI: Tobak och avvänjning [Tobacco and weaning]. 2009, Östersund: Statens folkhälsoinstitut (FHI) [Swedish National Institute of Public Health]
27.
go back to reference Boldemann C, Gilljam H, Lund KE, Helgason AR: Smoking cessation in general practice: the effects of a quitline. Nicotine Tob Res. 2006, 8 (6): 785-790. 10.1080/14622200601004059.CrossRefPubMed Boldemann C, Gilljam H, Lund KE, Helgason AR: Smoking cessation in general practice: the effects of a quitline. Nicotine Tob Res. 2006, 8 (6): 785-790. 10.1080/14622200601004059.CrossRefPubMed
28.
go back to reference Nohlert E, Tegelberg A, Tillgren P, Johansson P, Rosenblad A, Helgason AR: Comparison of a high and a low intensity smoking cessation intervention in a dentistry setting in Sweden: a randomized trial. BMC Publ Health. 2009, 9: 121-10.1186/1471-2458-9-121.CrossRef Nohlert E, Tegelberg A, Tillgren P, Johansson P, Rosenblad A, Helgason AR: Comparison of a high and a low intensity smoking cessation intervention in a dentistry setting in Sweden: a randomized trial. BMC Publ Health. 2009, 9: 121-10.1186/1471-2458-9-121.CrossRef
29.
go back to reference Prochaska JO, DiClemente CC: Stages and processes of self-change of smoking: toward an integrative model of change. J Consult Clin Psychol. 1983, 51 (3): 390-395.CrossRefPubMed Prochaska JO, DiClemente CC: Stages and processes of self-change of smoking: toward an integrative model of change. J Consult Clin Psychol. 1983, 51 (3): 390-395.CrossRefPubMed
30.
go back to reference Hosmer DW, Lemeshow S: Applied logistic regression. 1989, New York: Wiley Hosmer DW, Lemeshow S: Applied logistic regression. 1989, New York: Wiley
31.
go back to reference West R: The clinical significance of "small" effects of smoking cessation treatments. Addiction. 2007, 102 (4): 506-509.CrossRefPubMed West R: The clinical significance of "small" effects of smoking cessation treatments. Addiction. 2007, 102 (4): 506-509.CrossRefPubMed
32.
go back to reference Yudkin P, Hey K, Roberts S, Welch S, Murphy M, Walton R: Abstinence from smoking eight years after participation in randomised controlled trial of nicotine patch. BMJ. 2003, 327 (7405): 28-29. 10.1136/bmj.327.7405.28.CrossRefPubMedPubMedCentral Yudkin P, Hey K, Roberts S, Welch S, Murphy M, Walton R: Abstinence from smoking eight years after participation in randomised controlled trial of nicotine patch. BMJ. 2003, 327 (7405): 28-29. 10.1136/bmj.327.7405.28.CrossRefPubMedPubMedCentral
33.
go back to reference Galanti M, Holm Ivarsson B, Helgason A, Gilljam H: Smoking cessation: gender on the agenda. Drugs: education, prevention and policy. 2002, 9 (1): 71-84. 10.1080/09687630110086456. Galanti M, Holm Ivarsson B, Helgason A, Gilljam H: Smoking cessation: gender on the agenda. Drugs: education, prevention and policy. 2002, 9 (1): 71-84. 10.1080/09687630110086456.
34.
go back to reference Murray RP, Connett JE, Rand CS, Pan W, Anthonisen NR: Persistence of the effect of the Lung Health Study (LHS) smoking intervention over eleven years. Prev Med. 2002, 35 (4): 314-319. 10.1006/pmed.2002.1087.CrossRefPubMed Murray RP, Connett JE, Rand CS, Pan W, Anthonisen NR: Persistence of the effect of the Lung Health Study (LHS) smoking intervention over eleven years. Prev Med. 2002, 35 (4): 314-319. 10.1006/pmed.2002.1087.CrossRefPubMed
35.
go back to reference Murray RP, Gerald LB, Lindgren PG, Connett JE, Rand CS, Anthonisen NR: Characteristics of participants who stop smoking and sustain abstinence for 1 and 5 years in the Lung Health Study. Prev Med. 2000, 30 (5): 392-400. 10.1006/pmed.2000.0642.CrossRefPubMed Murray RP, Gerald LB, Lindgren PG, Connett JE, Rand CS, Anthonisen NR: Characteristics of participants who stop smoking and sustain abstinence for 1 and 5 years in the Lung Health Study. Prev Med. 2000, 30 (5): 392-400. 10.1006/pmed.2000.0642.CrossRefPubMed
36.
go back to reference Blondal T, Gudmundsson LJ, Olafsdottir I, Gustavsson G, Westin A: Nicotine nasal spray with nicotine patch for smoking cessation: randomised trial with six year follow up. BMJ. 1999, 318 (7179): 285-288. 10.1136/bmj.318.7179.285.CrossRefPubMedPubMedCentral Blondal T, Gudmundsson LJ, Olafsdottir I, Gustavsson G, Westin A: Nicotine nasal spray with nicotine patch for smoking cessation: randomised trial with six year follow up. BMJ. 1999, 318 (7179): 285-288. 10.1136/bmj.318.7179.285.CrossRefPubMedPubMedCentral
37.
go back to reference Socialstyrelsen: Befolkningens tandhälsa 2009 [The population´s oral health 2009] (in Swedish). 2010, Stockholm: Socialstyrelsen [The National Swedish Board of Health and Welfare] Socialstyrelsen: Befolkningens tandhälsa 2009 [The population´s oral health 2009] (in Swedish). 2010, Stockholm: Socialstyrelsen [The National Swedish Board of Health and Welfare]
38.
go back to reference Zhu SH, Stretch V, Balabanis M, Rosbrook B, Sadler G, Pierce JP: Telephone counseling for smoking cessation: effects of single-session and multiple-session interventions. J Consult Clin Psychol. 1996, 64 (1): 202-211.CrossRefPubMed Zhu SH, Stretch V, Balabanis M, Rosbrook B, Sadler G, Pierce JP: Telephone counseling for smoking cessation: effects of single-session and multiple-session interventions. J Consult Clin Psychol. 1996, 64 (1): 202-211.CrossRefPubMed
39.
go back to reference Gilpin E, Pierce JP: Measuring smoking cessation: problems with recall in the 1990 California Tobacco Survey. Cancer Epidemiol Biomarkers Prev. 1994, 3 (7): 613-617.PubMed Gilpin E, Pierce JP: Measuring smoking cessation: problems with recall in the 1990 California Tobacco Survey. Cancer Epidemiol Biomarkers Prev. 1994, 3 (7): 613-617.PubMed
40.
go back to reference Helgason AR, Dickman PW, Adolfsson J, Steineck G: Emotional isolation: prevalence and the effect on well-being among 50-80-year-old prostate cancer patients. Scand J Urol Nephrol. 2001, 35 (2): 97-101. 10.1080/003655901750170407.CrossRefPubMed Helgason AR, Dickman PW, Adolfsson J, Steineck G: Emotional isolation: prevalence and the effect on well-being among 50-80-year-old prostate cancer patients. Scand J Urol Nephrol. 2001, 35 (2): 97-101. 10.1080/003655901750170407.CrossRefPubMed
41.
go back to reference Alberg AJ, Patnaik JL, May JW, Hoffman SC, Gitchelle J, Comstock GW, Helzlsouer KJ: Nicotine replacement therapy use among a cohort of smokers. J Addict Dis. 2005, 24 (1): 101-113. 10.1300/J069v24n01_09.CrossRefPubMed Alberg AJ, Patnaik JL, May JW, Hoffman SC, Gitchelle J, Comstock GW, Helzlsouer KJ: Nicotine replacement therapy use among a cohort of smokers. J Addict Dis. 2005, 24 (1): 101-113. 10.1300/J069v24n01_09.CrossRefPubMed
42.
go back to reference Fagerstrom K, Rutqvist LE, Hughes JR: Snus as a smoking cessation aid: a randomized placebo-controlled trial. Nicotine Tob Res. 2012, 14 (3): 306-312. 10.1093/ntr/ntr214.CrossRefPubMed Fagerstrom K, Rutqvist LE, Hughes JR: Snus as a smoking cessation aid: a randomized placebo-controlled trial. Nicotine Tob Res. 2012, 14 (3): 306-312. 10.1093/ntr/ntr214.CrossRefPubMed
43.
go back to reference Lund KE, Scheffels J, McNeill A: The association between use of snus and quit rates for smoking: results from seven Norwegian cross-sectional studies. Addiction. 2011, 106 (1): 162-167. 10.1111/j.1360-0443.2010.03122.x.CrossRefPubMedPubMedCentral Lund KE, Scheffels J, McNeill A: The association between use of snus and quit rates for smoking: results from seven Norwegian cross-sectional studies. Addiction. 2011, 106 (1): 162-167. 10.1111/j.1360-0443.2010.03122.x.CrossRefPubMedPubMedCentral
44.
go back to reference Hung WT, Dunlop SM, Perez D, Cotter T: Use and perceived helpfulness of smoking cessation methods: results from a population survey of recent quitters. BMC Publ Health. 2011, 11: 592-10.1186/1471-2458-11-592.CrossRef Hung WT, Dunlop SM, Perez D, Cotter T: Use and perceived helpfulness of smoking cessation methods: results from a population survey of recent quitters. BMC Publ Health. 2011, 11: 592-10.1186/1471-2458-11-592.CrossRef
45.
go back to reference Etter JF, Perneger T, Ronchi A: Distributions of smokers by stage: International comparison and association with smoking prevalence. Prev Med. 1997, 26: 580-585. 10.1006/pmed.1997.0179.CrossRefPubMed Etter JF, Perneger T, Ronchi A: Distributions of smokers by stage: International comparison and association with smoking prevalence. Prev Med. 1997, 26: 580-585. 10.1006/pmed.1997.0179.CrossRefPubMed
46.
go back to reference Le Strat Y, Rehm J, Le Foll B: How generalisable to community samples are clinical trial results for treatment of nicotine dependence: a comparison of common eligibility criteria with respondents of a large representative general population survey. Tob Control. 2011, 20 (5): 338-343. 10.1136/tc.2010.038703.CrossRefPubMed Le Strat Y, Rehm J, Le Foll B: How generalisable to community samples are clinical trial results for treatment of nicotine dependence: a comparison of common eligibility criteria with respondents of a large representative general population survey. Tob Control. 2011, 20 (5): 338-343. 10.1136/tc.2010.038703.CrossRefPubMed
47.
go back to reference SRNT (Society for Research on Nicotine and Tobacco) Subcommittee on Biochemical Verification: Biochemical verification of tobacco use and cessation. Nicotine Tob Res. 2002, 4 (2): 149-159. 10.1080/14622200210123581.CrossRef SRNT (Society for Research on Nicotine and Tobacco) Subcommittee on Biochemical Verification: Biochemical verification of tobacco use and cessation. Nicotine Tob Res. 2002, 4 (2): 149-159. 10.1080/14622200210123581.CrossRef
Metadata
Title
Long-term follow-up of a high- and a low-intensity smoking cessation intervention in a dental setting– a randomized trial
Authors
Eva Nohlert
John Öhrvik
Åke Tegelberg
Per Tillgren
Ásgeir R Helgason
Publication date
01-12-2013
Publisher
BioMed Central
Published in
BMC Public Health / Issue 1/2013
Electronic ISSN: 1471-2458
DOI
https://doi.org/10.1186/1471-2458-13-592

Other articles of this Issue 1/2013

BMC Public Health 1/2013 Go to the issue